ID Q9LUT2_ARATH Unreviewed; 393 AA. AC Q9LUT2; DT 01-OCT-2000, integrated into UniProtKB/TrEMBL. DT 01-OCT-2000, sequence version 1. DT 15-JAN-2008, entry version 45. DE S-adenosylmethionine synthetase (EC 2.5.1.6). GN OrderedLocusNames=At3g17390; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; OC rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=20277480; PubMed=10819329; DOI=10.1093/dnares/7.2.131; RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.; RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC RT clones."; RL DNA Res. 7:131-135(2000). RN [2] RP NUCLEOTIDE SEQUENCE. RA Sato S., Nakamura Y., Kaneko T., Kato T., Asamizu E., Tabata S.; RL Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RA Kim C.J., Chen H., Cheuk R., Shinn P., Bowser L., Carninci P., RA Chan M.M., Chang C.H., Dale J.M., Hayashizaki Y., Hsuan V.W., RA Ishida J., Jones T., Kamiya A., Karlin-Neumann G., Kawai J., Lam B., RA Lee J.M., Lin J., Miranda M., Narusaka M., Nguyen M., Onodera C.S., RA Palm C.J., Quach H.L., Sakurai T., Satou M., Seki M., Southwick A., RA Tang C.C., Toriumi M., Wong C., Wu H.C., Yamada K., Yu G., Yuan S., RA Shinozaki K., Davis R.W., Theologis A., Ecker J.R.; RT "Arabidopsis ORF clones."; RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE. RA Yamada K., Chan M.M., Chang C.H., Dale J.M., Hsuan V.W., Lee J.M., RA Quach H.L., Tang C., Toriumi M., Wallender E.K., Wong C., Wu H.C., RA Yu G., Yuan S., Carninci P., Chen H., Cheuk R., Hayashizaki Y., RA Ishida J., Jones T., Kamiya A., Kawai J., Kim C.J., Narusaka M., RA Nguyen M., Palm C.J., Sakurai T., Satou M., Seki M., Shinn P., RA Southwick A., Tripp M.G., Wu T., Shinozaki K., Davis R.W., Ecker J.R., RA Theologis A.; RT "Arabidopsis Full Length cDNA Clones."; RL Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases. RN [5] RP NUCLEOTIDE SEQUENCE. RA Southwick A., Karlin-Neumann G., Nguyen M., Tripp M., Miranda M., RA Palm C.J., Bowser L., Jones T., Banh J., Carninci P., Chen H., RA Cheuk R., Chung M.K., Hayashizaki Y., Ishida J., Kamiya A., Kawai J., RA Kim C., Lin J., Liu S.X., Narusaka M., Pham P.K., Sakano H., RA Sakurai T., Satou M., Seki M., Shinn P., Yamada K., Shinozaki K., RA Ecker J., Theologis A., Davis R.W.; RL Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. RN [6] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22088475; PubMed=12093376; RA Haas B.J., Volfovsky N., Town C.D., Troukhan M., Alexandrov N., RA Feldmann K.A., Flavell R.B., White O., Salzberg S.L.; RT "Full-length messenger RNA sequences greatly improve genome RT annotation."; RL Genome Biol. 3:RESEARCH0029-RESEARCH0029(2002). RN [7] RP NUCLEOTIDE SEQUENCE. RA Alexandrov N.A., Troukhan M.E., Brover V.V., Flavell R.B., RA Feldmann K.A.; RT "Features of Arabidopsis genes and genome discovered using full-length RT cDNAs."; RL Plant Mol. Biol. 60:71-87(2006). RN [8] RP NUCLEOTIDE SEQUENCE. RA Brover V., Troukhan M., Alexandrov N., Lu Y.-P., Flavell R., RA Feldmann K.; RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. RN [9] RP NUCLEOTIDE SEQUENCE. RA Cheuk R., Chen H., Kim C.J., Koesema E., Meyers M.C., Shinn P., RA Tracy S.E., Banh J., Bowser L., Carninci P., Chung M.K., RA Goldsmith A.D., Hayashizaki Y., Ishida J., Jones T., Kamiya A., RA Karlin-Neumann G., Kawai J., Lam B., Lee J.M., Lin J., Liu S.X., RA Miranda M., Narusaka M., Nguyen M., Palm C.J., Pham P.K., Quach H.L., RA Sakano H., Sakurai T., Satou M., Seki M., Southwick A., Tang C.C., RA Toriumi M., Yamada K., Yu G., Shinozaki K., Davis R.W., Theologis A., RA Ecker J.R.; RT "Arabidopsis cDNA clones."; RL Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the formation of S-adenosylmethionine from CC methionine and ATP (By similarity). CC -!- CATALYTIC ACTIVITY: ATP + L-methionine + H(2)O = phosphate + CC diphosphate + S-adenosyl-L-methionine. CC -!- COFACTOR: Binds 1 potassium ion per subunit (By similarity). CC -!- COFACTOR: Binds 2 divalent ions per subunit. Magnesium or cobalt CC (By similarity). CC -!- PATHWAY: Activated methyl cycle. CC -!- SIMILARITY: Belongs to the AdoMet synthetase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY037214; AAK59799.1; -; mRNA. DR EMBL; AY120708; AAM53266.1; -; mRNA. DR EMBL; AY087184; AAM64740.1; -; mRNA. DR EMBL; BT000712; AAN31855.1; -; mRNA. DR EMBL; BT002665; AAO11581.1; -; mRNA. DR EMBL; AB022216; BAB02743.1; -; Genomic_DNA. DR RefSeq; NP_188365.1; -. DR UniGene; At.5781; -. DR HSSP; P13444; 1QM4. DR GeneID; 821003; -. DR TAIR; At3g17390; -. DR ArrayExpress; Q9LUT2; -. DR GO; GO:0009409; P:response to cold; IEP:TAIR. DR InterPro; IPR002133; S-AdoMet_synt. DR PANTHER; PTHR11964; S-AdoMet_synt; 1. DR Pfam; PF02773; S-AdoMet_synt_C; 1. DR Pfam; PF02772; S-AdoMet_synt_M; 1. DR Pfam; PF00438; S-AdoMet_synt_N; 1. DR PIRSF; PIRSF000497; MAT; 1. DR TIGRFAMs; TIGR01034; metK; 1. DR PROSITE; PS00376; ADOMET_SYNTHETASE_1; 1. DR PROSITE; PS00377; ADOMET_SYNTHETASE_2; 1. PE 2: Evidence at transcript level; KW ATP-binding; Complete proteome; Magnesium; Metal-binding; KW Nucleotide-binding; One-carbon metabolism; Potassium; Transferase. SQ SEQUENCE 393 AA; 42796 MW; 70034EC2B5E81867 CRC64; MESFLFTSES VNEGHPDKLC DQISDAILDA CLEQDPESKV ACETCTKTNM VMVFGEITTK ANVDYEQIVR KTCREIGFVS ADVGLDADNC KVLVNIEQQS PDIAQGVHGH LTKKPEEVGA GDQGHMFGYA TDETPELMPL THVLATKLGA KLTEVRKNGT CPWLRPDGKT QVTIEYINES GAMVPVRVHT VLISTQHDET VTNDEIAADL KEHVIKPVIP EKYLDEKTIF HLNPSGRFVI GGPHGDAGLT GRKIIIDTYG GWGAHGGGAF SGKDPTKVDR SGAYIVRQAA KSIVASGLAR RVIVQVSYAI GVPEPLSVFV DSYGTGKIPD KEILEIVKES FDFRPGMISI NLDLKRGGNG RFLKTAAYGH FGRDDADFTW EVVKPLKSNK VQA //