ID Q9LUT2 PRELIMINARY; PRT; 393 AA. AC Q9LUT2; DT 01-OCT-2000 (TrEMBLrel. 15, Created) DT 01-OCT-2000 (TrEMBLrel. 15, Last sequence update) DT 05-JUL-2004 (TrEMBLrel. 27, Last annotation update) DE S-adenosylmethionine synthase (AT3g17390/MGD8_20) (Putative s- DE adenosylmethionine synthetase). GN Name=At3g17390; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicots; rosids; OC eurosids II; Brassicales; Brassicaceae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=20277480; PubMed=10819329; RA Nakamura Y.; RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC RT clones."; RL DNA Res. 7:131-135(2000). RN [2] RP SEQUENCE FROM N.A. RA Sato S., Nakamura Y., Kaneko T., Kato T., Asamizu E., Tabata S.; RL Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases. RN [3] RP SEQUENCE FROM N.A. RA Cheuk R., Chen H., Kim C.J., Koesema E., Meyers M.C., Shinn P., RA Tracy S.E., Banh J., Bowser L., Carninci P., Chung M.K., RA Goldsmith A.D., Hayashizaki Y., Ishida J., Jones T., Kamiya A., RA Karlin-Neumann G., Kawai J., Lam B., Lee J.M., Lin J., Liu S.X., RA Miranda M., Narusaka M., Nguyen M., Palm C.J., Pham P.K., Quach H.L., RA Sakano H., Sakurai T., Satou M., Seki M., Southwick A., Tang C.C., RA Toriumi M., Yamada K., Yu G., Shinozaki K., Davis R.W., Theologis A., RA Ecker J.R.; RL Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases. RN [4] RP SEQUENCE FROM N.A. RX MEDLINE=22088475; PubMed=12093376; RA Haas B.J., Volfovsky N., Town C.D., Troukhan M., Alexandrov N., RA Feldmann K.A., Flavell R.B., White O., Salzberg S.L.; RT "Full-length messenger RNA sequences greatly improve genome RT annotation."; RL Genome Biol. 3:RESEARCH0029-RESEARCH0029(2002). RN [5] RP SEQUENCE FROM N.A. RA Brover V., Troukhan M., Alexandrov N., Lu Y.-P., Flavell R., RA Feldmann K.; RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. RN [6] RP SEQUENCE FROM N.A. RA Southwick A., Karlin-Neumann G., Nguyen M., Tripp M., Miranda M., RA Palm C.J., Bowser L., Jones T., Banh J., Carninci P., Chen H., RA Cheuk R., Chung M.K., Hayashizaki Y., Ishida J., Kamiya A., Kawai J., RA Kim C., Lin J., Liu S.X., Narusaka M., Pham P.K., Sakano H., RA Sakurai T., Satou M., Seki M., Shinn P., Yamada K., Shinozaki K., RA Ecker J., Theologis A., Davis R.W.; RL Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. RN [7] RP SEQUENCE FROM N.A. RA Yamada K., Chan M.M., Chang C.H., Dale J.M., Hsuan V.W., Lee J.M., RA Quach H.L., Tang C., Toriumi M., Wallender E.K., Wong C., Wu H.C., RA Yu G., Yuan S., Carninci P., Chen H., Cheuk R., Hayashizaki Y., RA Ishida J., Jones T., Kamiya A., Kawai J., Kim C.J., Narusaka M., RA Nguyen M., Palm C.J., Sakurai T., Satou M., Seki M., Shinn P., RA Southwick A., Tripp M.G., Wu T., Shinozaki K., Davis R.W., Ecker J.R., RA Theologis A.; RL Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases. RN [8] RP SEQUENCE FROM N.A. RA Kim C.J., Chen H., Cheuk R., Shinn P., Bowser L., Carninci P., RA Chan M.M., Chang C.H., Dale J.M., Hayashizaki Y., Hsuan V.W., RA Ishida J., Jones T., Kamiya A., Karlin-Neumann G., Kawai J., Lam B., RA Lee J.M., Lin J., Miranda M., Narusaka M., Nguyen M., Onodera C.S., RA Palm C.J., Quach H.L., Sakurai T., Satou M., Seki M., Southwick A., RA Tang C.C., Toriumi M., Wong C., Wu H.C., Yamada K., Yu G., Yuan S., RA Shinozaki K., Davis R.W., Theologis A., Ecker J.R.; RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the formation of S-adenosylmethionine from CC methionine and ATP. CC -!- CATALYTIC ACTIVITY: ATP + L-methionine + H(2)O = phosphate + CC diphosphate + S-adenosyl-L-methionine. CC -!- PATHWAY: Activated methyl cycle. CC -!- SIMILARITY: Belongs to the AdoMet synthetase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB022216; BAB02743.1; -. DR EMBL; AY037214; AAK59799.1; -. DR EMBL; AY087184; AAM64740.1; -. DR EMBL; AY120708; AAM53266.1; -. DR EMBL; BT000712; AAN31855.1; -. DR EMBL; BT002665; AAO11581.1; -. DR HSSP; P13444; 1QM4. DR GO; GO:0005524; F:ATP binding; IEA. DR GO; GO:0004478; F:methionine adenosyltransferase activity; IEA. DR GO; GO:0016740; F:transferase activity; IEA. DR GO; GO:0006730; P:one-carbon compound metabolism; IEA. DR InterPro; IPR002133; S-AdoMet_synt. DR Pfam; PF02773; S-AdoMet_synt_C; 1. DR Pfam; PF02772; S-AdoMet_synt_M; 1. DR Pfam; PF00438; S-AdoMet_synt_N; 1. DR PIRSF; PIRSF000497; MAT; 1. DR TIGRFAMs; TIGR01034; metK; 1. DR PROSITE; PS00376; ADOMET_SYNTHETASE_1; 1. DR PROSITE; PS00377; ADOMET_SYNTHETASE_2; 1. KW ATP-binding; Magnesium; Metal-binding; One-carbon metabolism; KW Potassium; Transferase. SQ SEQUENCE 393 AA; 42795 MW; 70034EC2B5E81867 CRC64; MESFLFTSES VNEGHPDKLC DQISDAILDA CLEQDPESKV ACETCTKTNM VMVFGEITTK ANVDYEQIVR KTCREIGFVS ADVGLDADNC KVLVNIEQQS PDIAQGVHGH LTKKPEEVGA GDQGHMFGYA TDETPELMPL THVLATKLGA KLTEVRKNGT CPWLRPDGKT QVTIEYINES GAMVPVRVHT VLISTQHDET VTNDEIAADL KEHVIKPVIP EKYLDEKTIF HLNPSGRFVI GGPHGDAGLT GRKIIIDTYG GWGAHGGGAF SGKDPTKVDR SGAYIVRQAA KSIVASGLAR RVIVQVSYAI GVPEPLSVFV DSYGTGKIPD KEILEIVKES FDFRPGMISI NLDLKRGGNG RFLKTAAYGH FGRDDADFTW EVVKPLKSNK VQA //