ID ENO2_HEVBR STANDARD; PRT; 445 AA. AC Q9LEI9; DT 16-OCT-2001 (Rel. 40, Created) DT 16-OCT-2001 (Rel. 40, Last sequence update) DT 16-OCT-2001 (Rel. 40, Last annotation update) DE Enolase 2 (EC 4.2.1.11) (2-phosphoglycerate dehydratase 2) (2-phospho- DE D-glycerate hydro-lyase 2) (Allergen Hev b 9). GN ENO2. OS Hevea brasiliensis (Para rubber tree). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicots; Rosidae; OC eurosids I; Malpighiales; Euphorbiaceae; Hevea. OX NCBI_TaxID=3981; RN [1] RP SEQUENCE FROM N.A. RC TISSUE=Latex; RA Wagner S., Hoffmann-Sommergruber K., Breiteneder H.; RT "characterization of crossreactive allergen from Hevea brasiliensis RT latex."; RL Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: 2-phospho-D-glycerate = phosphoenolpyruvate + CC H(2)O. CC -!- COFACTOR: MAGNESIUM IS REQUIRED FOR CATALYSIS AND FOR STABILIZING CC THE DIMER (BY SIMILARITY). CC -!- PATHWAY: GLYCOLYSIS. CC -!- SUBUNIT: HOMODIMER (BY SIMILARITY). CC -!- SUBCELLULAR LOCATION: Cytoplasmic. CC -!- DISEASE: INVOLVED IN LATEX ALLERGIC REACTIONS. CC -!- SIMILARITY: BELONGS TO THE ENOLASE FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ132581; CAC00533.1; -. DR HSSP; P00924; 1ONE. DR InterPro; IPR000941; Enolase. DR Pfam; PF00113; enolase; 1. DR PRINTS; PR00148; ENOLASE. DR ProDom; PD000902; Enolase; 1. DR PROSITE; PS00164; ENOLASE; 1. KW Lyase; Glycolysis; Magnesium; Multigene family; Allergen. FT ACT_SITE 164 164 BY SIMILARITY. FT METAL 251 251 MAGNESIUM (BY SIMILARITY). FT METAL 301 301 MAGNESIUM (BY SIMILARITY). FT METAL 328 328 MAGNESIUM (BY SIMILARITY). SQ SEQUENCE 445 AA; 47913 MW; C5B42954F0E83EC8 CRC64; MAITIVSVRA RQIFDSRGNP TVEADVKLSD GYLARAAVPR GASTGIYEAL ELRDGGSDYL GKGVSKAVEN VNIIIGPALV GKDPTDQVGI DNFMVQQLDG TVNEWGWCKQ KLGANAILAV SLAVCKAGAH VKGIPLYKHV ANLAGNKNLV LPVPAFNVIN GGSHAGNKLA MQEFMILPVG ASSFKEAMKM GAEVYHHLKS VIKKKYGQDA TNVGDEGGFA PNIQENKEGL ELLKTAIAKA GYTGKVVIGM DVAASEFYGS DKTYDLNFKE ENNNGSQKIS GDVLKDLYKS FVTEYPIVSI EDPFDQDDWE HYAKLTSEIG VKVQIVGDDL LVTNPKRVEK AIKEKACNAL LLKVNQIGSV TESIEAVKMS KRAGWGVMAS HRSGETEDTF IADLSVGLAT GQIKTGAPCR SERLAKYNQL LRIEEELGAE AVYAGANFRT PVEPY //