ID Q9JPU4_NEIME Unreviewed; 385 AA. AC Q9JPU4; DT 01-OCT-2000, integrated into UniProtKB/TrEMBL. DT 01-OCT-2000, sequence version 1. DT 01-OCT-2014, entry version 62. DE SubName: Full=PorA {ECO:0000313|EMBL:AAF42480.1}; DE Flags: Precursor {ECO:0000313|EMBL:AAF42480.1}; GN Name=porA {ECO:0000313|EMBL:AAF42480.1}; OS Neisseria meningitidis. OC Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; OC Neisseriaceae; Neisseria. OX NCBI_TaxID=487 {ECO:0000313|EMBL:AAF42480.1}; RN [1] {ECO:0000313|PIR:S18770} RP NUCLEOTIDE SEQUENCE. RX PubMed=1652557; RA Van Der Ley P.A., Heckels J.E., Virji M., Hoogerhout P., Poolman J.T.; RT "Topology of outer membrane porins in pathogenic Neisseria spp."; RL Infect. Immun. 59:2963-2971(1991). RN [2] {ECO:0000313|EMBL:AAF42480.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=90-18311 {ECO:0000313|EMBL:AAF42480.1}; RX PubMed=10710308; DOI=10.1126/science.287.5459.1816; RA Pizza M., Scarlato V., Masignani V., Giuliani M.M., Arico' B., RA Comanducci M., Jennings G.T., Baldi L., Bartolini E., Capecchi B., RA Galeotti C.L., Luzzi E., Manetti R., Marchetti E., Mora M., Nuti S., RA Ratti G., Santini L., Savino S., Scarselli M., Storni E., Zuo P., RA Broeker M., Hundt E., Knapp B., Blair E., Mason T., Tettelin H., RA Hood D.W., Jeffries A.C., Saunders N.J., Granoff D.M., Venter J.C., RA Moxon E.R., Grandi G., Rappuoli R.; RT "Identification of vaccine candidates against serogroup B RT meningococcus by whole-genome sequencing."; RL Science 287:1816-1820(2000). CC -!- SUBUNIT: Homotrimer. {ECO:0000256|RuleBase:RU000469}. CC -!- SUBCELLULAR LOCATION: Cell outer membrane CC {ECO:0000256|RuleBase:RU000469}; Multi-pass membrane protein CC {ECO:0000256|RuleBase:RU000469}. CC -!- SIMILARITY: Belongs to the Gram-negative porin family. CC {ECO:0000256|RuleBase:RU000469}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF226331; AAF42480.1; -; Genomic_DNA. DR PIR; S18770; S18770. DR ProteinModelPortal; Q9JPU4; -. DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW. DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW. DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW. DR Gene3D; 2.40.160.10; -; 1. DR InterPro; IPR017690; OM_insertion_C_omp85_target. DR InterPro; IPR023614; Porin_dom. DR InterPro; IPR001702; Porin_Gram-ve. DR InterPro; IPR013793; Porin_Gram-ve_CS. DR InterPro; IPR002299; Porin_Neis. DR Pfam; PF00267; Porin_1; 1. DR PRINTS; PR00182; ECOLNEIPORIN. DR PRINTS; PR00184; NEISSPPORIN. DR TIGRFAMs; TIGR03304; OMP85_target; 4. DR PROSITE; PS00576; GRAM_NEG_PORIN; 1. PE 3: Inferred from homology; KW Cell outer membrane {ECO:0000256|RuleBase:RU000469}; KW Ion transport {ECO:0000256|RuleBase:RU000469}; KW Membrane {ECO:0000256|RuleBase:RU000469}; KW Porin {ECO:0000256|RuleBase:RU000469}; KW Signal {ECO:0000313|EMBL:AAF42480.1}; KW Transmembrane {ECO:0000256|RuleBase:RU000469}; KW Transport {ECO:0000256|RuleBase:RU000469}. FT SIGNAL 1 19 Potential. {ECO:0000313|EMBL:AAF42480.1}. FT CHAIN 20 385 Potential. {ECO:0000313|EMBL:AAF42480.1}. FT /FTId=PRO_5000057735. SQ SEQUENCE 385 AA; 41557 MW; D7F62A122A634829 CRC64; MRKKLTALVL SALPLAAVAD VSLYGEIKAG VEGRNIQLQL TEPLQNIQPQ VTKRKSRIRT KISDFGSFIG FKGSEDLGEG LKAVWQLEQD VSVAGGGATQ WGNRESFIGL AGEFGTLRAG RVANQFDDAS QAIDPWDSNN DVASQLGIFK RHDDMPVSVR YDSPEFSGFS GSVQFVPAQN SKSAYTPAHF VQQPPKSQPT LVPAVVGKPG SDVYYAGLNY KNGGFAGNYA FKYAKHANVG RDAFELFLLG SGSDEAKGTD PLKNHQVHRL TGGYEEGGLN LALAAQLDLS ENGDKTKNST TEIAATASYR FGNAVPRISY AHGFDFIERG KKGENTSYDQ IIAGVDYDFS KRTSAIVSGA WLKRNTGIGN YTQINAASVG LRHKF //