ID Q9H2E0_HUMAN Unreviewed; 83 AA. AC Q9H2E0; DT 01-MAR-2001, integrated into UniProtKB/TrEMBL. DT 01-MAR-2001, sequence version 1. DT 04-FEB-2015, entry version 62. DE SubName: Full=Neuropilin-1 {ECO:0000313|EMBL:AAG41893.1}; DE SubName: Full=Putative uncharacterized protein DKFZp686M1967 {ECO:0000313|EMBL:CAH10397.1}; DE Flags: Fragment; GN Name=NRP1 {ECO:0000313|EMBL:AAG41893.1}; GN Synonyms=DKFZp686M1967 {ECO:0000313|EMBL:CAH10397.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AAG41893.1}; RN [1] {ECO:0000313|EMBL:AAG41893.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=11112349; DOI=10.1006/geno.2000.6381; RA Rossignol M., Gagnon M.L., Klagsbrun M.; RT "Genomic organization of human neuropilin-1 and neuropilin-2 genes: RT identification and distribution of splice variants and soluble RT isoforms."; RL Genomics 70:211-222(2000). RN [2] {ECO:0000313|EMBL:CAH10397.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Endometrium carcinoma cell line {ECO:0000313|EMBL:CAH10397.1}; RG The German cDNA Consortium; RA Bahr A., Lauber J., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., RA Han M., Wiemann S.; RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF280548; AAG41893.1; -; Genomic_DNA. DR EMBL; AL833608; CAH10397.1; -; mRNA. DR UniGene; Hs.131704; -. DR UniGene; Hs.653996; -. DR ProteinModelPortal; Q9H2E0; -. DR BindingDB; Q9H2E0; -. DR ChiTaRS; NRP1; human. DR Bgee; Q9H2E0; -. DR ExpressionAtlas; Q9H2E0; baseline and differential. DR GO; GO:0030424; C:axon; IEA:Ensembl. DR GO; GO:0009986; C:cell surface; IEA:Ensembl. DR GO; GO:0005769; C:early endosome; IEA:Ensembl. DR GO; GO:0030426; C:growth cone; IEA:Ensembl. DR GO; GO:0005883; C:neurofilament; IEA:Ensembl. DR GO; GO:0043025; C:neuronal cell body; IEA:Ensembl. DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl. DR GO; GO:0097443; C:sorting endosome; IEA:Ensembl. DR GO; GO:0017154; F:semaphorin receptor activity; IEA:Ensembl. DR GO; GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:Ensembl. DR GO; GO:0060978; P:angiogenesis involved in coronary vascular morphogenesis; IEA:Ensembl. DR GO; GO:0048846; P:axon extension involved in axon guidance; IEA:Ensembl. DR GO; GO:0007413; P:axonal fasciculation; IEA:Ensembl. DR GO; GO:0060385; P:axonogenesis involved in innervation; IEA:Ensembl. DR GO; GO:0021785; P:branchiomotor neuron axon guidance; IEA:Ensembl. DR GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IEA:Ensembl. DR GO; GO:0071679; P:commissural neuron axon guidance; IEA:Ensembl. DR GO; GO:0060982; P:coronary artery morphogenesis; IEA:Ensembl. DR GO; GO:0016358; P:dendrite development; IEA:Ensembl. DR GO; GO:0060666; P:dichotomous subdivision of terminal units involved in salivary gland branching; IEA:Ensembl. DR GO; GO:0035767; P:endothelial cell chemotaxis; IEA:InterPro. DR GO; GO:0021612; P:facial nerve structural organization; IEA:Ensembl. DR GO; GO:0021828; P:gonadotrophin-releasing hormone neuronal migration to the hypothalamus; IEA:Ensembl. DR GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl. DR GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl. DR GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl. DR GO; GO:1901166; P:neural crest cell migration involved in autonomic nervous system development; IEA:Ensembl. DR GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl. DR GO; GO:0050918; P:positive chemotaxis; IEA:Ensembl. DR GO; GO:0048842; P:positive regulation of axon extension involved in axon guidance; IEA:Ensembl. DR GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl. DR GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl. DR GO; GO:1902336; P:positive regulation of retinal ganglion cell axon guidance; IEA:Ensembl. DR GO; GO:1902946; P:protein localization to early endosome; IEA:Ensembl. DR GO; GO:0061441; P:renal artery morphogenesis; IEA:Ensembl. DR GO; GO:0009611; P:response to wounding; IEA:Ensembl. DR GO; GO:0061299; P:retina vasculature morphogenesis in camera-type eye; IEA:Ensembl. DR GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl. DR GO; GO:1902287; P:semaphorin-plexin signaling pathway involved in axon guidance; IEA:Ensembl. DR GO; GO:0061549; P:sympathetic ganglion development; IEA:Ensembl. DR GO; GO:0097490; P:sympathetic neuron projection extension; IEA:Ensembl. DR GO; GO:0097491; P:sympathetic neuron projection guidance; IEA:Ensembl. DR GO; GO:0021637; P:trigeminal nerve structural organization; IEA:Ensembl. DR GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl. DR GO; GO:1902378; P:VEGF-activated neuropilin signaling pathway involved in axon guidance; IEA:Ensembl. DR Gene3D; 2.60.120.290; -; 1. DR InterPro; IPR000859; CUB_dom. DR InterPro; IPR027146; NRP1. DR PANTHER; PTHR10127:SF616; PTHR10127:SF616; 1. DR Pfam; PF00431; CUB; 1. DR SUPFAM; SSF49854; SSF49854; 1. DR PROSITE; PS01180; CUB; 1. PE 2: Evidence at transcript level; FT NON_TER 83 83 {ECO:0000313|EMBL:AAG41893.1}. SQ SEQUENCE 83 AA; 9376 MW; 398AA6A822A407BB CRC64; MERGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA PDPYQRIMIN FNPHFDLEDR DCK //