ID AGL72_ARATH Reviewed; 211 AA. AC Q9FLH5; A0MFN4; Q1PDK7; DT 13-APR-2016, integrated into UniProtKB/Swiss-Prot. DT 01-MAR-2001, sequence version 1. DT 16-OCT-2019, entry version 143. DE RecName: Full=MADS-box protein AGL72; DE AltName: Full=Protein AGAMOUS-LIKE 72; GN Name=AGL72; GN OrderedLocusNames=At5g51860 {ECO:0000312|Araport:AT5G51860}; GN ORFNames=MJM18.1 {ECO:0000312|EMBL:BAB11255.1}; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; OC Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). RC STRAIN=cv. Columbia; TISSUE=Flower; RX PubMed=12837945; DOI=10.1105/tpc.011544; RA Parenicova L., de Folter S., Kieffer M., Horner D.S., Favalli C., RA Busscher J., Cook H.E., Ingram R.M., Kater M.M., Davies B., RA Angenent G.C., Colombo L.; RT "Molecular and phylogenetic analyses of the complete MADS-box RT transcription factor family in Arabidopsis: new openings to the MADS RT world."; RL Plant Cell 15:1538-1551(2003). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX PubMed=9628582; DOI=10.1093/dnares/5.1.41; RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N., RA Tabata S.; RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. RT Sequence features of the regions of 1,456,315 bp covered by nineteen RT physically assigned P1 and TAC clones."; RL DNA Res. 5:41-54(1998). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX PubMed=10718197; DOI=10.1093/dnares/7.1.31; RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H., RA Tabata S.; RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC RT clones."; RL DNA Res. 7:31-63(2000). RN [4] RP GENOME REANNOTATION. RC STRAIN=cv. Columbia; RX PubMed=27862469; DOI=10.1111/tpj.13415; RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S., RA Town C.D.; RT "Araport11: a complete reannotation of the Arabidopsis thaliana RT reference genome."; RL Plant J. 89:789-804(2017). RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). RC STRAIN=cv. Columbia; RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x; RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.; RT "Simultaneous high-throughput recombinational cloning of open reading RT frames in closed and open configurations."; RL Plant Biotechnol. J. 4:317-324(2006). RN [6] RP FUNCTION, DEVELOPMENTAL STAGE, AND DISRUPTION PHENOTYPE. RX PubMed=21609362; DOI=10.1111/j.1365-313x.2011.04653.x; RA Dorca-Fornell C., Gregis V., Grandi V., Coupland G., Colombo L., RA Kater M.M.; RT "The Arabidopsis SOC1-like genes AGL42, AGL71 and AGL72 promote RT flowering in the shoot apical and axillary meristems."; RL Plant J. 67:1006-1017(2011). CC -!- FUNCTION: MADS-box transcription factor that acts with AGL42 and CC AGL71 in the control of flowering time. Promotes flowering at the CC shoot apical and axillary meristems. Seems to act through a CC gibberellin-dependent pathway. Interacts genetically with SOC1 and CC its expression is directly regulated by SOC1. CC {ECO:0000269|PubMed:21609362}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE- CC ProRule:PRU00251}. CC -!- ALTERNATIVE PRODUCTS: CC Event=Alternative splicing; Named isoforms=2; CC Name=1; CC IsoId=Q9FLH5-1; Sequence=Displayed; CC Name=2; CC IsoId=Q9FLH5-2; Sequence=VSP_058214; CC Note=No experimental confirmation available. {ECO:0000305}; CC -!- DEVELOPMENTAL STAGE: Expressed in the shoot apical meristem (SAM) CC during the vegetative phase and the floral transition. After CC floral transition, expressed in apical meristem (AM), CC inflorescence meristem (IM) and floral primordia. CC {ECO:0000269|PubMed:21609362}. CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth CC conditions. {ECO:0000269|PubMed:21609362}. CC -!- SEQUENCE CAUTION: CC Sequence=ABK28751.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY141221; AAN52785.1; -; mRNA. DR EMBL; AB010074; BAB11255.1; -; Genomic_DNA. DR EMBL; AB025623; BAB11255.1; JOINED; Genomic_DNA. DR EMBL; CP002688; AED96136.1; -; Genomic_DNA. DR EMBL; CP002688; AED96137.1; -; Genomic_DNA. DR EMBL; DQ447061; ABE66238.1; -; mRNA. DR EMBL; DQ653360; ABK28751.1; ALT_SEQ; mRNA. DR RefSeq; NP_001078745.1; NM_001085276.1. [Q9FLH5-2] DR RefSeq; NP_199999.1; NM_124565.2. [Q9FLH5-1] DR SMR; Q9FLH5; -. DR IntAct; Q9FLH5; 1. DR STRING; 3702.AT5G51860.1; -. DR PaxDb; Q9FLH5; -. DR EnsemblPlants; AT5G51860.1; AT5G51860.1; AT5G51860. [Q9FLH5-1] DR EnsemblPlants; AT5G51860.2; AT5G51860.2; AT5G51860. [Q9FLH5-2] DR GeneID; 835261; -. DR Gramene; AT5G51860.1; AT5G51860.1; AT5G51860. [Q9FLH5-1] DR Gramene; AT5G51860.2; AT5G51860.2; AT5G51860. [Q9FLH5-2] DR KEGG; ath:AT5G51860; -. DR Araport; AT5G51860; -. DR TAIR; locus:2165386; AT5G51860. DR eggNOG; KOG0014; Eukaryota. DR eggNOG; COG5068; LUCA. DR HOGENOM; HOG000155301; -. DR InParanoid; Q9FLH5; -. DR OMA; EMATMVE; -. DR OrthoDB; 1235442at2759; -. DR PhylomeDB; Q9FLH5; -. DR PRO; PR:Q9FLH5; -. DR Proteomes; UP000006548; Chromosome 5. DR ExpressionAtlas; Q9FLH5; baseline and differential. DR GO; GO:0005634; C:nucleus; IBA:GO_Central. DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR. DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro. DR GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IBA:GO_Central. DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central. DR GO; GO:0008134; F:transcription factor binding; IBA:GO_Central. DR GO; GO:0044212; F:transcription regulatory region DNA binding; IBA:GO_Central. DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW. DR GO; GO:0007275; P:multicellular organism development; IBA:GO_Central. DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro. DR GO; GO:0009909; P:regulation of flower development; IMP:TAIR. DR CDD; cd00265; MADS_MEF2_like; 1. DR Gene3D; 3.40.1810.10; -; 1. DR InterPro; IPR033896; MADS_MEF2-like. DR InterPro; IPR002487; TF_Kbox. DR InterPro; IPR002100; TF_MADSbox. DR InterPro; IPR036879; TF_MADSbox_sf. DR Pfam; PF01486; K-box; 1. DR Pfam; PF00319; SRF-TF; 1. DR PRINTS; PR00404; MADSDOMAIN. DR SMART; SM00432; MADS; 1. DR SUPFAM; SSF55455; SSF55455; 1. DR PROSITE; PS51297; K_BOX; 1. DR PROSITE; PS50066; MADS_BOX_2; 1. PE 2: Evidence at transcript level; KW Alternative splicing; Complete proteome; Developmental protein; KW Differentiation; DNA-binding; Flowering; Nucleus; Reference proteome; KW Transcription; Transcription regulation. FT CHAIN 1 211 MADS-box protein AGL72. FT /FTId=PRO_0000436029. FT DOMAIN 1 61 MADS-box. {ECO:0000255|PROSITE- FT ProRule:PRU00251}. FT DOMAIN 88 187 K-box. {ECO:0000255|PROSITE- FT ProRule:PRU00629}. FT VAR_SEQ 172 180 Missing (in isoform 2). FT /FTId=VSP_058214. SQ SEQUENCE 211 AA; 24634 MW; 1926F4E45B9B0B95 CRC64; MVRGKIEIKK IENVTSRQVT FSKRRSGLFK KAHELSVLCD AQVAAMIFSQ KGRLYEFASS DIRNTIKRYA EYKREYFVAE THPIEQYVQG LKKEMVTMVK KIEVLEVHNR KMMGQSLDSC SVKELSEIAT QIEKSLHMVR LRKAKLYEDE LQKLKAKERE LKDERVRLSL KKTIYTHLCQ VGERPMGMPS GSKEKEDVET DLFIGFLKNR P //