ID NSTU2_ARATH Reviewed; 398 AA. AC Q9FG70; A0MFP6; Q8LB26; DT 12-APR-2017, integrated into UniProtKB/Swiss-Prot. DT 01-MAR-2001, sequence version 1. DT 03-AUG-2022, entry version 115. DE RecName: Full=Nucleotide-sugar uncharacterized transporter 2 {ECO:0000305}; GN OrderedLocusNames=At5g55950 {ECO:0000312|Araport:AT5G55950}; GN ORFNames=MYN21.6 {ECO:0000312|EMBL:BAB08660.1}; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H., RA Tabata S.; RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI."; RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases. RN [2] RP GENOME REANNOTATION. RC STRAIN=cv. Columbia; RX PubMed=27862469; DOI=10.1111/tpj.13415; RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S., RA Town C.D.; RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference RT genome."; RL Plant J. 89:789-804(2017). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=cv. Columbia; RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x; RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.; RT "Simultaneous high-throughput recombinational cloning of open reading RT frames in closed and open configurations."; RL Plant Biotechnol. J. 4:317-324(2006). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=cv. Columbia; RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W., RA Redman J.C., Wu H.C., Utterback T., Town C.D.; RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases. RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=cv. Columbia; RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K., RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., RA Shinozaki K.; RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."; RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases. RN [6] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., RA Feldmann K.A.; RT "Full-length cDNA from Arabidopsis thaliana."; RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. RN [7] RP GENE FAMILY. RX PubMed=25053812; DOI=10.1073/pnas.1406073111; RA Rautengarten C., Ebert B., Moreno I., Temple H., Herter T., Link B., RA Donas-Cofre D., Moreno A., Saez-Aguayo S., Blanco F., Mortimer J.C., RA Schultink A., Reiter W.D., Dupree P., Pauly M., Heazlewood J.L., RA Scheller H.V., Orellana A.; RT "The Golgi localized bifunctional UDP-rhamnose/UDP-galactose transporter RT family of Arabidopsis."; RL Proc. Natl. Acad. Sci. U.S.A. 111:11563-11568(2014). RN [8] RP GENE FAMILY. RX PubMed=25804536; DOI=10.1105/tpc.114.133827; RA Ebert B., Rautengarten C., Guo X., Xiong G., Stonebloom S., RA Smith-Moritz A.M., Herter T., Chan L.J., Adams P.D., Petzold C.J., RA Pauly M., Willats W.G., Heazlewood J.L., Scheller H.V.; RT "Identification and characterization of a Golgi-localized UDP-xylose RT transporter family from Arabidopsis."; RL Plant Cell 27:1218-1227(2015). CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane CC protein {ECO:0000255}. CC -!- SIMILARITY: Belongs to the TPT transporter family. TPT (TC 2.A.7.9) CC subfamily. {ECO:0000305}. CC -!- SEQUENCE CAUTION: CC Sequence=ABK28760.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB026659; BAB08660.1; -; Genomic_DNA. DR EMBL; CP002688; AED96702.1; -; Genomic_DNA. DR EMBL; DQ447080; ABE66252.1; -; mRNA. DR EMBL; DQ653372; ABK28760.1; ALT_SEQ; mRNA. DR EMBL; AK230288; BAF02090.1; -; mRNA. DR EMBL; AY087465; AAM65010.1; -; mRNA. DR RefSeq; NP_200406.1; NM_124977.4. DR AlphaFoldDB; Q9FG70; -. DR SMR; Q9FG70; -. DR STRING; 3702.AT5G55950.1; -. DR PaxDb; Q9FG70; -. DR PRIDE; Q9FG70; -. DR EnsemblPlants; AT5G55950.1; AT5G55950.1; AT5G55950. DR GeneID; 835693; -. DR Gramene; AT5G55950.1; AT5G55950.1; AT5G55950. DR KEGG; ath:AT5G55950; -. DR Araport; AT5G55950; -. DR TAIR; locus:2178373; AT5G55950. DR eggNOG; KOG1441; Eukaryota. DR HOGENOM; CLU_048347_1_1_1; -. DR InParanoid; Q9FG70; -. DR OMA; GVLLFQW; -. DR OrthoDB; 938634at2759; -. DR PhylomeDB; Q9FG70; -. DR PRO; PR:Q9FG70; -. DR Proteomes; UP000006548; Chromosome 5. DR ExpressionAtlas; Q9FG70; baseline and differential. DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0015297; F:antiporter activity; IBA:GO_Central. DR GO; GO:0005338; F:nucleotide-sugar transmembrane transporter activity; IBA:GO_Central. DR GO; GO:0005464; F:UDP-xylose transmembrane transporter activity; IBA:GO_Central. DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW. DR InterPro; IPR004853; Sugar_P_trans_dom. DR Pfam; PF03151; TPT; 1. PE 2: Evidence at transcript level; KW Membrane; Reference proteome; Sugar transport; Transmembrane; KW Transmembrane helix; Transport. FT CHAIN 1..398 FT /note="Nucleotide-sugar uncharacterized transporter 2" FT /id="PRO_0000439528" FT TRANSMEM 54..74 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 84..104 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 119..139 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 150..170 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 179..199 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 201..221 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 242..262 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 271..291 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 299..319 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 322..342 FT /note="Helical" FT /evidence="ECO:0000255" FT CONFLICT 17 FT /note="Missing (in Ref. 6; AAM65010)" FT /evidence="ECO:0000305" FT CONFLICT 330 FT /note="I -> V (in Ref. 6; AAM65010)" FT /evidence="ECO:0000305" SQ SEQUENCE 398 AA; 42644 MW; E4E9BF3B83901268 CRC64; MGLVDSLLGK DARKFLKRKD SDAAEAGRAL EELRSSLYNE LKTSEGAKRQ QQRFCGPVVA MSFNFVVAVG IILANKLVMG RVGFNFPIFL TLIHYTVAWI LLAFFKSLSL LPMSPPSKTT PFSSLFSLGA VMAFASGLAN TSLKHNSVGF YQMAKIAVTP TIVLAEFVLF KKTISSTKVM ALAVVSLGVA IATVTDLEFN LFGALVAVAW IIPSAINKIL WSNLQQQANW TALALMWKTT PFTVFFLLAL MPWLDPPGVL LFKWDLTNSS AILISALLGF LLQWSGALAL GATSATSHVV LGQFKTCVIL LGGYVIFGSD PGFISICGAI AALGGMSVYT WLNLPGKSID HMSNKQLPKQ NVTVSKPKAE ADDGGGETGV TVVSVDPLLS KTITANIV //