ID Q9DQ98_9GAMA Unreviewed; 158 AA. AC Q9DQ98; DT 01-MAR-2001, integrated into UniProtKB/TrEMBL. DT 01-MAR-2001, sequence version 1. DT 24-JUL-2024, entry version 70. DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417}; DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417}; DE Flags: Fragment; GN Name=Pol {ECO:0000313|EMBL:AAG39061.1}; OS Mandrillus herpesvirus 2. OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; OC Herpesvirales; Orthoherpesviridae; Gammaherpesvirinae; Rhadinovirus; OC Rhadinovirus macacinegamma5; Macacine gammaherpesvirus 5. OX NCBI_TaxID=144208 {ECO:0000313|EMBL:AAG39061.1}; RN [1] {ECO:0000313|EMBL:AAG39061.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=11090203; DOI=10.1128/JVI.74.24.11993-11999.2000; RA Lacoste V., Mauclere P., Dubreuil G., Lewis J., Georges-Courbot M.C., RA Rigoulet J., Petit T., Gessain A.; RT "Simian homologues of human gamma-2 and betaherpesviruses in mandrill and RT drill monkeys."; RL J. Virol. 74:11993-11999(2000). CC -!- CATALYTIC ACTIVITY: CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, CC ChEBI:CHEBI:173112; EC=2.7.7.7; CC Evidence={ECO:0000256|ARBA:ARBA00024632}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF282938; AAG39061.1; -; Genomic_DNA. DR GO; GO:0008296; F:3'-5'-DNA exonuclease activity; IEA:TreeGrafter. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC. DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro. DR GO; GO:0006287; P:base-excision repair, gap-filling; IEA:TreeGrafter. DR GO; GO:0045004; P:DNA replication proofreading; IEA:TreeGrafter. DR GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; IEA:TreeGrafter. DR GO; GO:0009432; P:SOS response; IEA:TreeGrafter. DR Gene3D; 3.90.1600.10; Palm domain of DNA polymerase; 1. DR InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom. DR InterPro; IPR043502; DNA/RNA_pol_sf. DR InterPro; IPR023211; DNA_pol_palm_dom_sf. DR InterPro; IPR050240; DNA_pol_type-B. DR PANTHER; PTHR10322; DNA POLYMERASE CATALYTIC SUBUNIT; 1. DR PANTHER; PTHR10322:SF23; DNA POLYMERASE DELTA CATALYTIC SUBUNIT; 1. DR Pfam; PF00136; DNA_pol_B; 1. DR SUPFAM; SSF56672; DNA/RNA polymerases; 1. PE 4: Predicted; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}. FT DOMAIN 1..158 FT /note="DNA-directed DNA polymerase family B FT multifunctional" FT /evidence="ECO:0000259|Pfam:PF00136" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AAG39061.1" FT NON_TER 158 FT /evidence="ECO:0000313|EMBL:AAG39061.1" SQ SEQUENCE 158 AA; 17794 MW; 19A23F568767465D CRC64; SIIQAHNLCY STMIHGRDLH LHPTLTQDDY ETFLLSGGPV HFVKKHKRES LLGRLLTVWL DKRREIRRAL AKCDDPSLKT ILDKQQLAIK VTCNAVYGFT GVASGLLPCI SIAETVTLRG RTMLEMSKSY VEALTPDELQ TRLRRAVHAG PSARFRVV //