ID Q9DQ23_9GAMR Unreviewed; 676 AA. AC Q9DQ23; DT 01-MAR-2001, integrated into UniProtKB/TrEMBL. DT 01-MAR-2001, sequence version 1. DT 02-OCT-2024, entry version 74. DE SubName: Full=Envelope protein {ECO:0000313|EMBL:AAG39910.1}; GN Name=env {ECO:0000313|EMBL:AAG39910.1}; OS Murine leukemia virus. OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; OC Ortervirales; Retroviridae; Orthoretrovirinae; Gammaretrovirus. OX NCBI_TaxID=11786 {ECO:0000313|EMBL:AAG39910.1}; RN [1] {ECO:0000313|EMBL:AAG39910.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=endogenous xenotropic {ECO:0000313|EMBL:AAG39910.1}; RX PubMed=12414952; DOI=10.1128/JVI.76.23.12112-12122.2002; RA Hook L.M., Jude B.A., Ter-Grigorov V.S., Hartley J.W., Morse H.C. 3rd, RA Trainin Z., Toder V., Chervonsky A.V., Golovkina T.V.; RT "Characterization of a novel murine retrovirus mixture that facilitates RT hematopoiesis."; RL J. Virol. 76:12112-12122(2002). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF288940; AAG39910.1; -; mRNA. DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW. DR GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW. DR CDD; cd09851; HTLV-1-like_HR1-HR2; 1. DR Gene3D; 1.10.287.210; -; 1. DR Gene3D; 3.90.310.10; ENV polyprotein, receptor-binding domain; 1. DR InterPro; IPR008981; FMuLV_rcpt-bd. DR InterPro; IPR018154; TLV/ENV_coat_polyprotein. DR PANTHER; PTHR10424:SF77; BC035947 PROTEIN-RELATED; 1. DR PANTHER; PTHR10424; VIRAL ENVELOPE PROTEIN; 1. DR Pfam; PF00429; TLV_coat; 1. DR SUPFAM; SSF49830; ENV polyprotein, receptor-binding domain; 1. DR SUPFAM; SSF58069; Virus ectodomain; 1. PE 2: Evidence at transcript level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Fusion of virus membrane with host cell membrane KW {ECO:0000256|ARBA:ARBA00022521}; KW Fusion of virus membrane with host membrane KW {ECO:0000256|ARBA:ARBA00022521}; KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022804}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}; KW Viral attachment to host cell {ECO:0000256|ARBA:ARBA00022804}; KW Viral envelope protein {ECO:0000256|ARBA:ARBA00022879, KW ECO:0000313|EMBL:AAG39910.1}; KW Viral penetration into host cytoplasm {ECO:0000256|ARBA:ARBA00022521}; KW Virion {ECO:0000256|ARBA:ARBA00022844}; KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00022521}. FT TRANSMEM 616..642 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT REGION 287..320 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 519..546 FT /evidence="ECO:0000256|SAM:Coils" SQ SEQUENCE 676 AA; 74354 MW; 9031F1921127C682 CRC64; MACSTLSKSP KDKIDPRDLL IPLILFLSLK GARSAAPGSS PHQVYNITWE VTNGDRETVW AISGNHPLWT WWPVLTPDLC MLALHGTPHW GLEYQAPYSS PPGPPCCSGS GGSSPGCSRD CDEPLTSLTP RCNTAWNRLK LDQVTHKSSE GFYVCPGPHR PRWARSCGGP ESFYCASWGC ETTGRAYWKP TSSWDYITVD NNLTTNQAVQ VCKDNKWCNP LAIQFTNAGR QVTSWMTGHY WGLRLYVSGQ DPGLTFGIRL KYQNLGPRVP IGPNPVLADQ LSFPLPNPLP KPAKSPPVSN STPTMISPSP TPTQPPPAGT GDRLLNLVQG AYQALNLTNP DKTQECWLCL VSGPPYYEGV AVLGTYSNHT SAPTNCSVAS QHKLTLSEVT GRGLCIGTVP KTHQALCNTT LKANKGSYYL VAPAGTMWAC NTGLTPCLSA TVLNRTTDYC VLVELWPRVT YHPPSYVYSQ FEKSYRHKRE PVSLTLALLL GGLTMGGIAA GVGTGTTALV ATQQFQQLHA AVQDDLKEVE KSITNLEKSL TSLSEVVLQN RRGLDLLFLK EGGLCAALKE ECCFYADHTG LVRDSMAKLR ERLTQRQKLF ESSQGWFEGW FNRSPWFTTL ISTIMGPLII LLLILLFGPC ILNRLVQFVK DRISVVQALV LTQQYHQLKP LECEPQ //