ID Q9DJY8_9ENTO Unreviewed; 233 AA. AC Q9DJY8; DT 01-MAR-2001, integrated into UniProtKB/TrEMBL. DT 01-MAR-2001, sequence version 1. DT 03-APR-2007, entry version 35. DE Polyprotein (Fragment). OS Human coxsackievirus A20. OC Viruses; ssRNA positive-strand viruses, no DNA stage; Picornaviridae; OC Enterovirus. OX NCBI_TaxID=42782; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=MG-423/94; RX MEDLINE=21064585; PubMed=11125161; RA Caro V., Guillot S., Delpeyroux F., Crainic R.; RT "Molecular strategy for 'serotyping' of human enteroviruses."; RL J. Gen. Virol. 82:79-91(2001). CC -!- FUNCTION: Capsid proteins VP1, VP2, VP3 and VP4 form a closed CC capsid enclosing the viral positive strand RNA genome. VP4 lies on CC the inner surface of the protein shell formed by VP1, VP2 and VP3. CC All the three latter proteins contains a beta-sheet structure CC called beta-barrel jelly roll (By similarity). CC -!- FUNCTION: RNA-directed RNA polymerase replicates genomic and CC antigenomic RNA by recognizing replications specific signals (By CC similarity). CC -!- CATALYTIC ACTIVITY: Selective cleavage of Gln-|-Gly bond in the CC poliovirus polyprotein. In other picornavirus reactions Glu may be CC substituted for Gln, and Ser or Thr for Gly. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ279184; CAC08133.1; -; Genomic_RNA. DR HSSP; P03300; 2PLV. DR SMR; Q9DJY8; 1-107. DR MEROPS; C03.020; -. DR GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW. DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. DR GO; GO:0031079; F:picornain 3C activity; IEA:InterPro. DR GO; GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW. DR GO; GO:0016032; P:viral reproduction; IEA:InterPro. DR InterPro; IPR009003; Pept_Ser_Cys. DR InterPro; IPR000081; Peptidase_C3. DR InterPro; IPR011565; Peptidase_C3_2. DR InterPro; IPR001676; Picornavirus_capsid. DR Pfam; PF00947; Pico_P2A; 1. DR Pfam; PF00073; Rhv; 1. DR ProDom; PD001306; Peptidase_C3_2; 1. KW Core protein. FT CHAIN <1 107 VP1 protein. FT /FTId=PRO_5000066207. FT CHAIN 108 >233 2A protein. FT /FTId=PRO_5000066208. FT NON_TER 1 1 FT NON_TER 233 233 SQ SEQUENCE 233 AA; 25697 MW; D1058CA9CDDFB6ED CRC64; IPYVGIANAY SNFYDGCATV PIEGETTDPC AAYYGATSIN DFGILAVRVV NEHNPVQVSS KIRVYMKPKH VRVWCPRPPR AVPYFGPGVD YKGDALTPLS TKSLTTYGFG HQNKAVYTAG YKICNYHLAT QEDLSNAVNV MWNRDLLVTE SKAQGTDSIA RCTCNAGVYY CESRRKYYPV SFIGPTFQYM EANDYYPARY QSHMLIGYGF ASPGDCGGIL RCQHGVIGII TAG //