ID Q9DDE0_BRARE PRELIMINARY; PRT; 393 AA. AC Q9DDE0; DT 01-MAR-2001, integrated into UniProtKB/TrEMBL. DT 01-MAR-2001, sequence version 1. DT 18-APR-2006, entry version 31. DE Meis2.1 protein (Myeloid ecotropic viral integration site 2.1). GN Name=meis2.1; OS Brachydanio rerio (Zebrafish) (Danio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=21184127; PubMed=11287203; DOI=10.1016/S0925-4773(01)00299-4; RA Zerucha T., Prince V.E.; RT "Cloning and developmental expression of a zebrafish meis2 homeobox RT gene."; RL Mech. Dev. 102:247-250(2001). RN [2] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Embryo; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). RN [3] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Embryo; RA Director MGC Project; RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Sequence-specific transcription factor which is part of CC a developmental regulatory system that provides cells with CC specific positional identities on the anterior-posterior axis (By CC similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ300652; CAC19011.1; -; mRNA. DR EMBL; BC066375; AAH66375.1; -; mRNA. DR HSSP; P40427; 1B8I. DR SMR; Q9DDE0; 276-335. DR Ensembl; ENSDARG00000027795; Danio rerio. DR ZFIN; ZDB-GENE-000210-23; meis2.1. DR GO; GO:0005634; C:nucleus; IEA. DR GO; GO:0003700; F:transcription factor activity; IEA. DR GO; GO:0007275; P:development; IEA. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA. DR InterPro; IPR001356; Homeobox. DR InterPro; IPR012287; Homeodomain-rel. DR InterPro; IPR009057; Homeodomain_like. DR Pfam; PF00046; Homeobox; 1. DR ProDom; PD000010; Homeobox; 1. DR SMART; SM00389; HOX; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. KW DNA-binding; Developmental protein; Homeobox; Nuclear protein; KW Transcription; Transcription regulation. SQ SEQUENCE 393 AA; 43043 MW; F8ABE55EAF8190E9 CRC64; MLMAQRYEDL AHYGGGMDGV GVPTSMYGDP HAPRPLPQVH HLNHGPPPHA NQHYGAHAPH SIMPSSMGSA VNDALKRDKD QIYGHPLFPL LALVFEKCEL ATCTPREPGV AGGDVCSSDS FNEDIAVFAK QIRAEKPLFS SNPELDNLMI QSIQVLRFHL LELEKVHELC DNFCHRYISC LKGKMPIDLV IDERDGCKSD FDDLSGSSTN LADHNPASWR DMDDAHSTPS VGTPGPSSGG HASQSGDNSS ELGDGLDNSL ASPGTGDEDD QDKKRQKKRG IFPKVATNIM RAWLFQHLTH PYPSEEQKKQ LAQDTGLTIL QVNNWFINAR RRIVQPMIDQ SNRAVSQGTA YSPDGQPMGG FVLDGQQHMG LRPGGPMGGM GMNMGMDGQW HYM //