ID Q9BY07_HUMAN PRELIMINARY; PRT; 1137 AA. AC Q9BY07; DT 01-JUN-2001, integrated into UniProtKB/TrEMBL. DT 01-JUN-2001, sequence version 1. DT 17-OCT-2006, entry version 23. DE Sodium bicarbonate cotransporter NBC4a. GN Name=SLC4A5; Synonyms=NBC4; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Testes; RX MEDLINE=20537950; PubMed=11087115; DOI=10.1080/15216540050176539; RA Pushkin A., Abuladze N., Newman D., Lee I., Xu G., Kurtz I.; RT "Two C-terminal variants of NBC4, a new member of the sodium RT bicarbonate cotransporter family: cloning, characterization, and RT localization."; RL IUBMB Life 50:13-19(2000). RN [2] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Testes; RA Pushkin A., Abuladze N., Lee I., Newman D., Kurtz I.; RL Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF243499; AAK26741.1; -; mRNA. DR UniGene; Hs.469033; -. DR HSSP; P02730; 1BZK. DR Ensembl; ENSG00000188687; Homo sapiens. DR HGNC; HGNC:18168; SLC4A5. DR ArrayExpress; Q9BY07; -. DR GO; GO:0016021; C:integral to membrane; IEA. DR GO; GO:0016020; C:membrane; IEA. DR GO; GO:0005452; F:inorganic anion exchanger activity; IEA. DR GO; GO:0006820; P:anion transport; IEA. DR InterPro; IPR011531; HCO3_transpt_C. DR InterPro; IPR013769; HCO3_transpt_cyt. DR InterPro; IPR003020; HCO3_transpt_euk. DR InterPro; IPR003024; NaHCO3_transpt. DR PANTHER; PTHR11453; HCO3_transpt_euk; 3. DR Pfam; PF00955; HCO3_cotransp; 1. DR PRINTS; PR01231; HCO3TRNSPORT. DR PRINTS; PR01232; NAHCO3TRSPRT. DR TIGRFAMs; TIGR00834; ae; 1. SQ SEQUENCE 1137 AA; 126251 MW; 0A25B78FB8DFBA30 CRC64; MKVKEEKAGV GKLDHTNHRR RFPDQKECPP IHIGLPVPTY PQRKTDQKGH LSGLQKVHWG LRPDQPQQEL TGPGSGASSQ DSSMDLISRT RSPAAEQLQD ILGEEDEAPN PTLFTEMDTL QHDGDQMEWK ESARWIKFEE KVEEGGERWS KPHVSTLSLH SLFELRTCLQ TGTVLLDLDS GSLPQIIDDV IEKQIEDGLL RPELRERVSY VLLRRHRHQT KKPIHRSLAD IGKSVSTTNR SPARSPGAGP SLHHSTEDLR MRQSANYGRL CHAQSRSMND ISLTPNTDQR KNKFMKKIPK DSEASNVLVG EVDFLDQPFI AFVRLIQSAM LGGVTEVPVP TRFLFILLGP SGRAKSYNEI GRAIATLMVD DLFSDVAYKA RNREDLIAGI DEFLDEVIVL PPGEWDPNIR IEPPKKVPSA DKRKSVFSLA ELGQMNGSVG GGGGAPGGGN GGGGGGGSGG GAGSGGAGGT SSGDDGEMPA MHEIGEELIW TGRFFGGLCL DIKRKLPWFP SDFYDGFHIQ SISAILFIYL GCITNAITFG GLLGDATDNY QGVMESFLGT AMAGSLFCLF SGQPLIILSS TGPILIFEKL LFDFSKGNGL DYMEFRLWIG LHSAVQCLIL VATDASFIIK YITRFTEEGF STLISFIFIY DAIKKMIGAF KYYPINMDFK PNFITTYKCE CVAPDTVNTT VFNASAPLAP DTNASLYNLL NLTALDWSLL SKKECLSYGG RLLGNSCKFI PDLALMSFIL FFGTYSMTLT LKKFKFSRYF PTKVRALVAD FSIVFSILMF CGIDACFGLE TPKLHVPSVI KPPRPDRGWF VAPFGKNPWW VYPASILPAL LVTILIFMDQ QITAVIVNRK ENKLKKAAGY HLDLFWVGIL MALCSFMGLP WYVAATVISI AHIDSLKMET ETSAPGEQPQ FLGVREQRVT GIIVFILTGI SVFLAPILKC IPLPVLYGVF LYMGVASLNG IQMGTGGSEF KIQKKLTPFW ERCKLFLMPA KHQPDHAFLR HVPLRRIHLF TLVQILCLAV LWILKSTVAA IIFPVMILGL IIVRRLLDFI FSQHDLAWID NILPEKEKKE TDKKRKRKKG AHEDCDEEPQ FPPPSVIKIP MESVQSDPQN GIHCIARKRS SSWSYSL //