ID Q9BPQ2_DROME Unreviewed; 571 AA. AC Q9BPQ2; DT 01-JUN-2001, integrated into UniProtKB/TrEMBL. DT 01-JUN-2001, sequence version 1. DT 22-FEB-2023, entry version 118. DE SubName: Full=DGATAe protein {ECO:0000313|EMBL:BAB21551.1}; GN Name=GATAe {ECO:0000313|FlyBase:FBgn0038391}; GN Synonyms=dGATAe {ECO:0000313|EMBL:BAB21551.1}; GN ORFNames=CG10278 {ECO:0000313|FlyBase:FBgn0038391}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; OC Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:BAB21551.1}; RN [1] {ECO:0000313|EMBL:BAB21551.1} RP NUCLEOTIDE SEQUENCE. RA Okumura T., Murakami R.; RT "Drosophila endoderm-specific GATA factor gene, dGATAe."; RL Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB054996; BAB21551.1; -; mRNA. DR AlphaFoldDB; Q9BPQ2; -. DR EnsemblMetazoa; FBtr0083218; FBpp0082672; FBgn0038391. DR AGR; FB:FBgn0038391; -. DR FlyBase; FBgn0038391; GATAe. DR VEuPathDB; VectorBase:FBgn0038391; -. DR Bgee; FBgn0038391; Expressed in adult midgut (Drosophila) and 33 other tissues. DR ExpressionAtlas; Q9BPQ2; baseline and differential. DR GO; GO:0005634; C:nucleus; IDA:FlyBase. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; ISS:FlyBase. DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0019730; P:antimicrobial humoral response; IMP:FlyBase. DR GO; GO:0045165; P:cell fate commitment; IBA:GO_Central. DR GO; GO:0007492; P:endoderm development; IMP:FlyBase. DR GO; GO:1903703; P:enterocyte differentiation; IMP:FlyBase. DR GO; GO:0035883; P:enteroendocrine cell differentiation; IMP:FlyBase. DR GO; GO:0036335; P:intestinal stem cell homeostasis; IMP:FlyBase. DR GO; GO:0007494; P:midgut development; IMP:FlyBase. DR GO; GO:0010629; P:negative regulation of gene expression; IMP:FlyBase. DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central. DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IMP:FlyBase. DR CDD; cd00202; ZnF_GATA; 1. DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1. DR InterPro; IPR039355; Transcription_factor_GATA. DR InterPro; IPR000679; Znf_GATA. DR InterPro; IPR013088; Znf_NHR/GATA. DR PANTHER; PTHR10071:SF281; BOX A-BINDING FACTOR-RELATED; 1. DR PANTHER; PTHR10071; TRANSCRIPTION FACTOR GATA FAMILY MEMBER; 1. DR Pfam; PF00320; GATA; 1. DR PRINTS; PR00619; GATAZNFINGER. DR SMART; SM00401; ZnF_GATA; 1. DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1. DR PROSITE; PS00344; GATA_ZN_FINGER_1; 1. DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1. PE 2: Evidence at transcript level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00094}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}; KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00094}; KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00094}. FT DOMAIN 533..571 FT /note="GATA-type" FT /evidence="ECO:0000259|PROSITE:PS50114" FT REGION 125..165 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 219..298 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 16..43 FT /evidence="ECO:0000256|SAM:Coils" FT COMPBIAS 134..165 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 219..253 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 262..298 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 571 AA; 62104 MW; 85755AA1D75EAC0F CRC64; MVCKTISPSV NMQLKMEQQT TQQQQQQQQQ QQQQQQLQQQ QHQALTKQQL QLLDKIKLES SNGADQLAQQ TANNLDEQQE QQQQHQQQAA TSVGVVVQTG QAGVSEPEEQ YVVVPRNQRR ILTTAGTLEL NEAREGEPST NASNASSGSA SDSHIEYQRS AHQSPGATHY VQMAPRNAEV TEQVGAAAGA PPGTIFAYPI ICNGDDVAAI KIETLEKGEA TGESQQQQQQ LQQHQHQQQQ QCPTPNGASY GETIVISSEA EALQHHHQQQ QQHQQQQHQQ QHHQHQAAAA ASAAAQTVHI ATSSHGGTVR FVTEDVRFTT AGPETSASNM YYDVPVVDGS VHANESKTYA DLGNAYAPFP PSSSFSSNSY AATLQQGNTI YSVPGTGQFL AKSESGLNQT GLLRQTGPAT FQTISFEGGN GIEPLWASPA PPEYQSVQFS NFHPQVIDEY GSGNMSTSHW PPASSIGQYD GSLVTASSTS SPNHELKCEN CHGPFLRKGS EYFCPNCPAF MRMAPRITQR QAKPKAAAAP NNRRNGVTCA NCQTNSTTLW RRNNEGNPVC NACGLYYKLT T //