ID GPA4_CAEEL STANDARD; PRT; 358 AA. AC Q9BIG5; O44409; DT 28-FEB-2003 (Rel. 41, Created) DT 28-FEB-2003 (Rel. 41, Last sequence update) DT 24-JAN-2006 (Rel. 49, Last annotation update) DE Guanine nucleotide-binding protein alpha-4 subunit. GN Name=gpa-4; ORFNames=T07A9.7; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; OC Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RC STRAIN=Bristol N2; RA Cuppen E., Jansen G., Plasterk R.H.A.; RT "Interaction analysis of the complete G-alpha subfamily of RT heterotrimeric G proteins from Caenorhabditis elegans."; RL Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2; RX MEDLINE=99069613; PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). RN [3] RP SEQUENCE REVISION. RG WormBase consortium; RL Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases. RN [4] RP GENE FAMILY, AND NOMENCLATURE. RX PubMed=10192394; DOI=10.1038/7753; RA Jansen G., Thijssen K.L., Werner P., van der Horst M., Hazendonk E., RA Plasterk R.H.A.; RT "The complete family of genes encoding G proteins of Caenorhabditis RT elegans."; RL Nat. Genet. 21:414-419(1999). CC -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are CC involved as modulators or transducers in various transmembrane CC signaling systems. CC -!- SUBUNIT: G proteins are composed of 3 units; alpha, beta and CC gamma. The alpha chain contains the guanine nucleotide binding CC site. CC -!- SIMILARITY: Belongs to the G-alpha family. G(i/o/t/z) subfamily. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY008127; AAG32080.1; -; mRNA. DR EMBL; AF036706; AAK39279.2; -; Genomic_DNA. DR PIR; T32578; T32578. DR HSSP; P04896; 1AZT. DR Ensembl; T07A9.7; Caenorhabditis elegans. DR WormBase; WBGene00001666; gpa-4. DR WormPep; T07A9.7; CE31599. DR InterPro; IPR001019; Gprotein_alph_bd. DR InterPro; IPR001408; Gprotein_alpha_I. DR InterPro; IPR011025; GproteinA_insert. DR Pfam; PF00503; G-alpha; 1. DR PRINTS; PR00318; GPROTEINA. DR PRINTS; PR00441; GPROTEINAI. DR ProDom; PD000281; Gprotein_alpha; 1. DR SMART; SM00275; G_alpha; 1. KW Complete proteome; GTP-binding; Lipoprotein; Multigene family; KW Myristate; Nucleotide-binding; Palmitate; Transducer. FT INIT_MET 0 0 By similarity. FT NP_BIND 38 45 GTP (By similarity). FT NP_BIND 202 206 GTP (By similarity). FT NP_BIND 271 274 GTP (By similarity). FT LIPID 1 1 N-myristoyl glycine (By similarity). FT LIPID 2 2 S-palmitoyl cysteine (By similarity). SQ SEQUENCE 358 AA; 41540 MW; 9390547E29E2D3DE CRC64; GCFHSTGSEA KKRSKLIDEQ LRHDHERCVG EIKLLLLGAG ESGKSTIVRQ MRILHETGFN KQEQMAYRPV VFSNMVQSML AILKAMQPLN ISFTDAAREE DARMFISHFL HVNNAELSEA FSLELSDLMK QLWMDEGVKK CVKRAHEYQL NDSAEYYFNA LDRISSSSYL PTQDDILRAR VKSTGIVETT FMYKDLCFKM FDVGGQRSER KKWIHCFDSV TAVIFCVALS EYDLRLAEDQ TMNRMHESMQ LFDSIVNNCW FTETSIILFL NKMDIFEERI RYTPLTVCFP EYQGGMTITE TSTFIQSRFE ILNKRQTPAQ KEIYSHFTCA TDTNNIRFVF DAVTDIIIRN NLYLCGLY //