ID H2AE_HUMAN STANDARD; PRT; 127 AA. AC Q99878; DT 01-OCT-2000 (Rel. 40, Created) DT 01-OCT-2000 (Rel. 40, Last sequence update) DT 01-OCT-2000 (Rel. 40, Last annotation update) DE HISTONE H2A.E (H2A/E). GN H2AFE. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=98102829; PubMed=9439656; RA Albig W., Doenecke D.; RT "The human histone gene cluster at the D6S105 locus."; RL Hum. Genet. 101:284-294(1997). CC -!- SUBUNIT: THE NUCLEOSOME IS AN OCTAMER CONTAINING TWO MOLECULES OF CC H2A, H2B, H3, AND H4; WHICH WRAP APPROXIMATELY 146 BP OF DNA. CC -!- SUBCELLULAR LOCATION: NUCLEAR. CC -!- SIMILARITY: BELONGS TO THE HISTONE H2A FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z83736; CAB06031.1; -. DR MIM; 602791; -. DR InterPro; IPR000166; -. DR InterPro; IPR002119; -. DR Pfam; PF00125; histone; 1. DR PRINTS; PR00620; HISTONEH2A. DR PROSITE; PS00046; HISTONE_H2A; 1. KW Chromosomal protein; Nucleosome core; Nuclear protein; DNA-binding; KW Multigene family; Acetylation. FT INIT_MET 0 0 BY SIMILARITY. FT MOD_RES 1 1 ACETYLATION (BY SIMILARITY). FT MOD_RES 5 5 ACETYLATION (BY SIMILARITY). FT MOD_RES 9 9 ACETYLATION (BY SIMILARITY). FT BINDING 119 119 UBIQUITIN (BY SIMILARITY). SQ SEQUENCE 127 AA; 13805 MW; FAED13FE8230C415 CRC64; SGRGKQGGKA RAKAKTRSSR AGLQFPVGRV HRLLRKGNYA ERVGAGAPVY LAAVLEYLTA EILELAGNAA RDNKKTRIIP RHLQLAIRND EELNKLLGKV TIAQGGVLPN IQAVLLPKKT ESHHKTK //