ID Q96X46 PRELIMINARY; PRT; 438 AA. AC Q96X46; DT 01-DEC-2001 (TrEMBLrel. 19, Created) DT 01-DEC-2001 (TrEMBLrel. 19, Last sequence update) DT 01-MAR-2004 (TrEMBLrel. 26, Last annotation update) DE Enolase (EC 4.2.1.11) (2-phosphoglycerate dehydratase) (2-phospho-D- DE glycerate hydro-lyase). OS Penicillium citrinum. OC Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Penicillium. OX NCBI_TaxID=5077; RN [1] RP SEQUENCE FROM N.A. RA Shen H.; RT "Molecular cloning and characterization of the enolase allergen from RT Penicillium citrinum."; RL Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: 2-phospho-D-glycerate = phosphoenolpyruvate + CC H(2)O. CC -!- COFACTOR: Magnesium is required for catalysis and for stabilizing CC the dimer (By similarity). CC -!- PATHWAY: Glycolysis. CC -!- SUBUNIT: Homodimer (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasmic (By similarity). CC -!- SIMILARITY: BELONGS TO THE ENOLASE FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF254643; AAK51201.1; -. DR GO; GO:0000015; C:phosphopyruvate hydratase complex; IEA. DR GO; GO:0016829; F:lyase activity; IEA. DR GO; GO:0000287; F:magnesium ion binding; IEA. DR GO; GO:0004634; F:phosphopyruvate hydratase activity; IEA. DR GO; GO:0006096; P:glycolysis; IEA. DR InterPro; IPR000941; Enolase. DR Pfam; PF00113; Enolase_C; 1. DR Pfam; PF03952; Enolase_N; 1. DR PRINTS; PR00148; ENOLASE. DR ProDom; PD000902; Enolase; 1. DR TIGRFAMs; TIGR01060; eno; 1. DR PROSITE; PS00164; ENOLASE; 1. KW Glycolysis; Lyase; Magnesium. SQ SEQUENCE 438 AA; 47275 MW; 48EA499055C9DE84 CRC64; MPIAKVHARS VYVSRGNPTV EVDVVTETGL HRAIVPSGAS TGQHEAVELR DGDKAKWGGK GVLKAVKNVN ETIGPALIKE NIDVKDQAKV DEFLNKLDGT ANKGNLGANA ILGVSLAIAK AAAAEKGVPL YVHISDLAGT KKPYVLPVPF QNVLNGGSHA GGRLAFQEFM IVPDTAESFS EGLRQGAEVY QKLKALAKKK YGQSAGNVGD EGGVAPDIQT AEEALDLITE AIEQAGYTGK ISIAMDVASS EFYKTDAKKY DLDFKNPDSD PTKWLTYEQL ADLYKSLAAK YPIVSIEDPF AEDDWEAWSY FYKTSDFQIV GDDLTVTNPL RIKKAIELKS CNALLLKVNQ IGTLTESIQA AKDSYADNWG VMVSHRSGET EDVTIADIAV GLRSGQIKTG APARSERLAK LNQILRIEEE LGENAIYAGK NFRTSVNL //