ID OR4CC_HUMAN STANDARD; PRT; 309 AA. AC Q96R67; Q6IF49; DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot. DT 10-OCT-2003, sequence version 2. DT 30-MAY-2006, entry version 34. DE Olfactory receptor 4C12 (Olfactory receptor OR11-259). GN Name=OR4C12; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 66-278. RX MEDLINE=22202146; PubMed=12213199; DOI=10.1006/geno.2002.6830; RA Fuchs T., Malecova B., Linhart C., Sharan R., Khen M., Herwig R., RA Shmulevich D., Elkon R., Steinfath M., O'Brien J.K., Radelof U., RA Lehrach H., Lancet D., Shamir R.; RT "DEFOG: a practical scheme for deciphering families of genes."; RL Genomics 80:295-302(2002). RN [2] RP IDENTIFICATION. RX PubMed=14983052; DOI=10.1073/pnas.0307882100; RA Malnic B., Godfrey P.A., Buck L.B.; RT "The human olfactory receptor gene family."; RL Proc. Natl. Acad. Sci. U.S.A. 101:2584-2589(2004). CC -!- FUNCTION: Putative odorant receptor. CC -!- SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein. CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. CC -!- WEB RESOURCE: NAME=Human Olfactory Receptor Data Exploratorium CC (HORDE); CC URL="http://bip.weizmann.ac.il/cgi-bin/HORDE/showGene.pl?key=symbol&value=OR4C12". CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF399576; AAK95061.1; -; Genomic_DNA. DR EMBL; BK004413; DAA04811.1; -; Genomic_DNA. DR UniGene; Hs.553669; -. DR HGNC; HGNC:15168; OR4C12. DR LinkHub; Q96R67; -. DR InterPro; IPR000276; GPCR_Rhodpsn. DR InterPro; IPR000725; Olfact_rcpt. DR Pfam; PF00001; 7tm_1; 1. DR PRINTS; PR00237; GPCRRHODOPSN. DR PRINTS; PR00245; OLFACTORYR. DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; FALSE_NEG. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. KW G-protein coupled receptor; Glycoprotein; Membrane; Olfaction; KW Receptor; Sensory transduction; Transducer; Transmembrane. FT CHAIN 1 309 Olfactory receptor 4C12. FT /FTId=PRO_0000150533. FT TOPO_DOM 1 23 Extracellular (Potential). FT TRANSMEM 24 47 1 (Potential). FT TOPO_DOM 48 55 Cytoplasmic (Potential). FT TRANSMEM 56 77 2 (Potential). FT TOPO_DOM 78 98 Extracellular (Potential). FT TRANSMEM 99 118 3 (Potential). FT TOPO_DOM 119 137 Cytoplasmic (Potential). FT TRANSMEM 138 156 4 (Potential). FT TOPO_DOM 157 193 Extracellular (Potential). FT TRANSMEM 194 217 5 (Potential). FT TOPO_DOM 218 233 Cytoplasmic (Potential). FT TRANSMEM 234 256 6 (Potential). FT TOPO_DOM 257 267 Extracellular (Potential). FT TRANSMEM 268 287 7 (Potential). FT TOPO_DOM 288 309 Cytoplasmic (Potential). FT CARBOHYD 6 6 N-linked (GlcNAc...) (Potential). FT DISULFID 95 187 By similarity. SQ SEQUENCE 309 AA; 34491 MW; 3C6AD9FA309457C9 CRC64; MEKKKNVTEF ILIGLTQNPI MEKVTFVVFL VLYMITLSGN LLIVVTITTS QALSSPMYFF LTHLSLIDTV YSSSSAPKLI VDSFQEKKII SFNGCMAQAY AEHIFGATEI ILLTVMACDC YVAICKPLNY TTIMSHSLCI LLVAVAWVGG FLHATIQILF TVWLPFCGPN VIGHFMCDLY PLLKLVCIDT HTLGLFVAVN SGFICLLNFL ILVVSYVIIL RSLKNNSLEG RCKALSTCIS HIIVVVLFFV PCIFVYLRSV TTLPIDKAVA VFYTMVVPML NPVVYTLRNA EVKSAIRKLW RKKVTSDND //