ID O4CC_HUMAN STANDARD; PRT; 309 AA. AC Q96R67; DT 10-OCT-2003 (Rel. 42, Created) DT 10-OCT-2003 (Rel. 42, Last sequence update) DT 29-MAR-2004 (Rel. 43, Last annotation update) DE Olfactory receptor 4C12. GN OR4C12. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP SEQUENCE OF 66-278 FROM N.A. RX MEDLINE=22202146; PubMed=12213199; RA Fuchs T., Malecova B., Linhart C., Sharan R., Khen M., Herwig R., RA Shmulevich D., Elkon R., Steinfath M., O'Brien J.K., Radelof U., RA Lehrach H., Lancet D., Shamir R.; RT "DEFOG: a practical scheme for deciphering families of genes."; RL Genomics 80:295-302(2002). CC -!- FUNCTION: Putative odorant receptor. CC -!- SUBCELLULAR LOCATION: Integral membrane protein. CC -!- SIMILARITY: Belongs to family 1 of G-protein coupled receptors. CC -!- DATABASE: NAME=Human Olfactory Receptor Data Exploratorium (HORDE); CC WWW="http://bioinformatics.weizmann.ac.il/cgi-bin/HORDE/showGene.pl?key=symbol&value=OR4C12". CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF399576; AAK95061.1; -. DR Genew; HGNC:15168; OR4C12. DR InterPro; IPR000276; GPCR_Rhodpsn. DR Pfam; PF00001; 7tm_1; 1. DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; FALSE_NEG. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. KW G-protein coupled receptor; Transmembrane; Glycoprotein; KW Multigene family; Olfaction. FT DOMAIN 1 23 Extracellular (Potential). FT TRANSMEM 24 47 1 (Potential). FT DOMAIN 48 55 Cytoplasmic (Potential). FT TRANSMEM 56 77 2 (Potential). FT DOMAIN 78 98 Extracellular (Potential). FT TRANSMEM 99 118 3 (Potential). FT DOMAIN 119 137 Cytoplasmic (Potential). FT TRANSMEM 138 156 4 (Potential). FT DOMAIN 157 193 Extracellular (Potential). FT TRANSMEM 194 217 5 (Potential). FT DOMAIN 218 233 Cytoplasmic (Potential). FT TRANSMEM 234 256 6 (Potential). FT DOMAIN 257 267 Extracellular (Potential). FT TRANSMEM 268 287 7 (Potential). FT DOMAIN 288 309 Cytoplasmic (Potential). FT DISULFID 95 187 By similarity. FT CARBOHYD 6 6 N-linked (GlcNAc...) (Potential). SQ SEQUENCE 309 AA; 34491 MW; 3C6AD9FA309457C9 CRC64; MEKKKNVTEF ILIGLTQNPI MEKVTFVVFL VLYMITLSGN LLIVVTITTS QALSSPMYFF LTHLSLIDTV YSSSSAPKLI VDSFQEKKII SFNGCMAQAY AEHIFGATEI ILLTVMACDC YVAICKPLNY TTIMSHSLCI LLVAVAWVGG FLHATIQILF TVWLPFCGPN VIGHFMCDLY PLLKLVCIDT HTLGLFVAVN SGFICLLNFL ILVVSYVIIL RSLKNNSLEG RCKALSTCIS HIIVVVLFFV PCIFVYLRSV TTLPIDKAVA VFYTMVVPML NPVVYTLRNA EVKSAIRKLW RKKVTSDND //