ID S2538_HUMAN Reviewed; 304 AA. AC Q96DW6; Q9NWX2; DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot. DT 01-DEC-2001, sequence version 1. DT 22-JUL-2008, entry version 45. DE RecName: Full=Solute carrier family 25 member 38; GN Name=SLC25A38; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Carcinoma; RX PubMed=14702039; DOI=10.1038/ng1285; RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.; RT "Complete sequencing and characterization of 21,243 full-length human RT cDNAs."; RL Nat. Genet. 36:40-45(2004). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RA Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.; RT "Cloning of human full open reading frames in Gateway(TM) system entry RT vector (pDONR201)."; RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Skin; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [4] RP IDENTIFICATION. RX PubMed=16949250; DOI=10.1016/j.ygeno.2006.06.016; RA Haitina T., Lindblom J., Renstroem T., Fredriksson R.; RT "Fourteen novel human members of mitochondrial solute carrier family RT 25 (SLC25) widely expressed in the central nervous system."; RL Genomics 88:779-790(2006). CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the mitochondrial carrier family. CC -!- SIMILARITY: Contains 3 Solcar repeats. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK000558; BAA91253.1; -; mRNA. DR EMBL; CR457242; CAG33523.1; -; mRNA. DR EMBL; BC013194; AAH13194.1; -; mRNA. DR RefSeq; NP_060345.2; -. DR UniGene; Hs.369615; -. DR Ensembl; ENSG00000144659; Homo sapiens. DR GeneID; 54977; -. DR KEGG; hsa:54977; -. DR HGNC; HGNC:26054; SLC25A38. DR MIM; 610819; gene. DR HOGENOM; Q96DW6; -. DR HOVERGEN; Q96DW6; -. DR ArrayExpress; Q96DW6; -. DR CleanEx; HS_SLC25A38; -. DR InterPro; IPR002067; Mit_carrier. DR InterPro; IPR001993; Mitoch_carrier. DR PANTHER; PTHR11896; Mitoch_carrier; 1. DR Pfam; PF00153; Mito_carr; 3. DR PRINTS; PR00926; MITOCARRIER. DR PROSITE; PS50920; SOLCAR; 3. PE 2: Evidence at transcript level; KW Membrane; Mitochondrion; Mitochondrion inner membrane; Polymorphism; KW Repeat; Transmembrane; Transport. FT CHAIN 1 304 Solute carrier family 25 member 38. FT /FTId=PRO_0000291802. FT TRANSMEM 31 51 1 (Potential). FT TRANSMEM 89 109 2 (Potential). FT TRANSMEM 127 147 3 (Potential). FT TRANSMEM 176 198 4 (Potential). FT TRANSMEM 214 234 5 (Potential). FT TRANSMEM 282 302 6 (Potential). FT REPEAT 25 114 Solcar 1. FT REPEAT 121 205 Solcar 2. FT REPEAT 215 299 Solcar 3. FT VARIANT 66 66 R -> G (in dbSNP:rs34127778). FT /FTId=VAR_032862. FT CONFLICT 239 239 D -> G (in Ref. 1; BAA91253). SQ SEQUENCE 304 AA; 33566 MW; 026B8121C40F8FF0 CRC64; MIQNSRPSLL QPQDVGDTVE TLMLHPVIKA FLCGSISGTC STLLFQPLDL LKTRLQTLQP SDHGSRRVGM LAVLLKVVRT ESLLGLWKGM SPSIVRCVPG VGIYFGTLYS LKQYFLRGHP PTALESVMLG VGSRSVAGVC MSPITVIKTR YESGKYGYES IYAALRSIYH SEGHRGLFSG LTATLLRDAP FSGIYLMFYN QTKNIVPHDQ VDATLIPITN FSCGIFAGIL ASLVTQPADV IKTHMQLYPL KFQWIGQAVT LIFKDYGLRG FFQGGIPRAL RRTLMAAMAW TVYEEMMAKM GLKS //