ID Q95WK4_ANOQU Unreviewed; 153 AA. AC Q95WK4; DT 01-DEC-2001, integrated into UniProtKB/TrEMBL. DT 01-DEC-2001, sequence version 1. DT 13-JUL-2010, entry version 32. DE RecName: Full=Glucose-6-phosphate 1-dehydrogenase; DE EC=1.1.1.49; DE Flags: Fragment; GN Name=G6pd; OS Anopheles quadrimaculatus (Common malaria mosquito). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; OC Anophelinae; Anopheles. OX NCBI_TaxID=7166; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22112021; PubMed=12116652; DOI=10.1080/106351501750435095; RA Krzywinski J., Wilkerson R.C., Besansky N.J.; RT "Toward understanding Anophelinae (Diptera, Culicidae) phylogeny: RT insights from nuclear single-copy genes and the weight of evidence."; RL Syst. Biol. 50:540-556(2001). CC -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate + NADP(+) = D-glucono- CC 1,5-lactone 6-phosphate + NADPH. CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway. CC -!- SIMILARITY: Belongs to the glucose-6-phosphate dehydrogenase CC family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF317809; AAL18428.1; -; Genomic_DNA. DR HSSP; P11413; 1QKI. DR SMR; Q95WK4; 1-152. DR GO; GO:0005488; F:binding; IEA:InterPro. DR GO; GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IEA:EC. DR GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW. DR GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW. DR InterPro; IPR001282; G6P_DH. DR InterPro; IPR022674; G6P_DH_NAD-bd. DR InterPro; IPR016040; NAD(P)-bd_dom. DR Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1. DR PANTHER; PTHR23429; G6PDH; 1. DR Pfam; PF00479; G6PD_N; 1. DR PRINTS; PR00079; G6PDHDRGNASE. PE 3: Inferred from homology; KW Carbohydrate metabolism; Glucose metabolism; NADP; Oxidoreductase. FT NON_TER 1 1 FT NON_TER 153 153 SQ SEQUENCE 153 AA; 17901 MW; 48F4D50B38AC19DD CRC64; LWWLFRDNLV PSDTKFVGYA RSKLSVAELK EKCRQYMKVK DAELEKFDEF WSVNFYVAGS YDSRRDFELL NQEIAKFEVG RAANRLFYLA LPPSVFESVT VHIRNTCMGE KGWNRIIVEK PFGRDASSSN ALSAHLSKLF SEDQLYRIDH YLV //