ID Q95Q34_CAEEL Unreviewed; 529 AA. AC Q95Q34; DT 01-DEC-2001, integrated into UniProtKB/TrEMBL. DT 01-JUN-2003, sequence version 2. DT 29-MAY-2007, entry version 44. DE Hypothetical protein. GN ORFNames=Y105E8B.3; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; OC Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2; RX MEDLINE=99069613; PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). CC -!- FUNCTION: Component of the EKC/KEOPS complex which promotes both CC telomere uncapping and telomere elongation (By similarity). The CC complex is required for efficient recruitment of transcriptional CC coactivators. Important for bud site selection (By similarity). CC -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL132877; CAC70109.2; -; Genomic_DNA. DR UniGene; Cel.17199; -. DR Ensembl; Y105E8B.3; Caenorhabditis elegans. DR KEGG; cel:Y105E8B.3; -. DR WormBase; WBGene00013688; Y105E8B.3. DR WormPep; Y105E8B.3; CE33542. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. DR InterPro; IPR015285; RIO2_kinase_wHTH_N. DR InterPro; IPR000687; RIO_kinase. DR Pfam; PF01163; RIO1; 1. DR Pfam; PF09202; Rio2_N; 1. DR PROSITE; PS01245; RIO1; 1. KW Activator; Chromosomal protein; Complete proteome; DNA-binding; KW Hypothetical protein; Kinase; Serine/threonine-protein kinase; KW Telomere; Transcription; Transcription regulation; Transferase. SQ SEQUENCE 529 AA; 60485 MW; 0671C8143EFB8D21 CRC64; MGRMNVSMMR YLEGDHFRVL IAVEMGMKNH EVVPLALVSA IAGIHRGGVA RTLNDLCKHS LVAFERSKKF DGYRLTIRGY DYLALRALCS REVVGSVGNQ IGIGKESDVY VGGDPELNDL CLKFHRLGRT SFRKIKEKRD YHKKRKSASW LYLSRLAAAK EFAFLKALQE RGFPVPKAVD VCRHLVVMQL VVGQTLCNVT HVEDAGALYD RLMALIVKMA RHGVIHGDFN EFNLIMLEDE RIVMIDFPQM VSIDHPNAEY YFDRDVTCVR TFFKRKFDYE SEDWPKFDEV ERKGNMDVLL EASGFTKKMA LDLNKAYDEG DFLAHCEQEL RNRQEEDLGE DEDDSDDSKS MEDIQEEPED LEKDHEELQA QENTVKQQKI VLSQTTRFTD WLSDATNQLE AVDLDALKSE EGYKDIELPP EDFKRPADSE NDDENDEDEE EGEEEDADGH VAVEEQVAKV VKKKRVPSGA RSVASSAATF TAEDVKRRLA LDRKRNKEKI RLKVKGKQSA VGRNRKDNKD VIAEYAGWI //