ID S45A3_MACFA Reviewed; 553 AA. AC Q95KI5; Q95KC5; DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot. DT 01-DEC-2001, sequence version 1. DT 10-AUG-2010, entry version 36. DE RecName: Full=Solute carrier family 45 member 3; DE AltName: Full=Prostate cancer-associated protein 6; DE AltName: Full=Prostein; GN Name=SLC45A3; Synonyms=PCANAP6, PRST; ORFNames=QmoA-10594, QtrA-11310; OS Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=9541; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Medulla oblongata, and Temporal cortex; RA Osada N., Hida M., Kusuda J., Tanuma R., Iseki K., Hirai M., Terao K., RA Suzuki Y., Sugano S., Hashimoto K.; RT "Isolation of full-length cDNA clones from macaque brain cDNA RT libraries."; RL Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein CC (Potential). CC -!- SIMILARITY: Belongs to the glycoside-pentoside-hexuronide (GPH) CC cation symporter transporter (TC 2.A.2) family. CC -!- SEQUENCE CAUTION: CC Sequence=BAB60745.1; Type=Erroneous initiation; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB060851; BAB46871.1; -; mRNA. DR EMBL; AB062977; BAB60745.1; ALT_INIT; mRNA. DR ProteinModelPortal; Q95KI5; -. DR HOVERGEN; HBG053519; -. DR OrthoDB; EOG9FXTTJ; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro. DR InterPro; IPR011701; MFS_1. DR InterPro; IPR016196; MFS_general_subst_transpt. DR Pfam; PF07690; MFS_1; 1. DR SUPFAM; SSF103473; MFS_gen_substrate_transporter; 1. PE 2: Evidence at transcript level; KW Membrane; Transmembrane; Transmembrane helix; Transport. FT CHAIN 1 553 Solute carrier family 45 member 3. FT /FTId=PRO_0000122520. FT TRANSMEM 19 39 Helical; Name=1; (Potential). FT TRANSMEM 52 72 Helical; Name=2; (Potential). FT TRANSMEM 88 108 Helical; Name=3; (Potential). FT TRANSMEM 120 140 Helical; Name=4; (Potential). FT TRANSMEM 161 181 Helical; Name=5; (Potential). FT TRANSMEM 198 218 Helical; Name=6; (Potential). FT TRANSMEM 275 295 Helical; Name=7; (Potential). FT TRANSMEM 323 343 Helical; Name=8; (Potential). FT TRANSMEM 353 373 Helical; Name=9; (Potential). FT TRANSMEM 382 402 Helical; Name=10; (Potential). FT TRANSMEM 522 542 Helical; Name=11; (Potential). FT COMPBIAS 455 458 Poly-Pro. FT CONFLICT 165 165 A -> T (in Ref. 1; BAB60745). FT CONFLICT 342 342 M -> V (in Ref. 1; BAB60745). SQ SEQUENCE 553 AA; 59393 MW; 0718F3A91FB3BF1E CRC64; MVQRLWVSRL LRHRKAQLLL INLLTFGLEV CLAAGITYVP PLLLEVGVEE KFMTMVLGIG PVLGLVSVPL LGSASDHWRG RYGRRRPFIW ALSLGILLSL FLIPRAGWLA GLLCPDPRPL ELALLILGVG LLDFCGQVCF TPLEALLSDL FRDPDHCRQA YSVYAFMISL GGCLGYLLPA IDWDTSALAP YLGTQEECLF GLLTLIFLTC VAATLLVAEE AALGPAEPAE GLSAPSLPSH CCPCWARLAF RNLGALLPRL HQLCCRMPRT LRRLFVAELC SWMALMTFTL FYTDFVGEGL YQGVPRAELG TEARRHYDEG VRMGSLGLFL QCAISLVFSL VMDRLVQRFG TRAVYLASVA AFPVAAGATC LSHSVAVVTA SAALTGFTFS ALQILPYTLA SLYHRERQVF LPKYRGDAGG TSSEDSLMTS FLPGPKPGAP FPNGHVGAGG SGLLPPPPAL CGASACDVSV RVVVGEPTEA RVVPGRGICL DLAILDSAFL LSQVAPSLFM GSIVQLSQSV TAYMVSAAGL GLVAIYFATQ VVFDKSDLAK YSV //