ID NU1C_WHEAT Reviewed; 362 AA. AC Q95H43; DT 10-OCT-2002, integrated into UniProtKB/Swiss-Prot. DT 27-JUN-2006, sequence version 2. DT 16-OCT-2019, entry version 72. DE RecName: Full=NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic {ECO:0000255|HAMAP-Rule:MF_01350}; DE EC=7.1.1.- {ECO:0000255|HAMAP-Rule:MF_01350}; DE AltName: Full=NAD(P)H dehydrogenase subunit 1 {ECO:0000255|HAMAP-Rule:MF_01350}; DE Short=NDH subunit 1 {ECO:0000255|HAMAP-Rule:MF_01350}; DE AltName: Full=NADH-plastoquinone oxidoreductase subunit 1 {ECO:0000255|HAMAP-Rule:MF_01350}; GN Name=ndhA {ECO:0000255|HAMAP-Rule:MF_01350}; OS Triticum aestivum (Wheat). OG Plastid; Chloroplast. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum. OX NCBI_TaxID=4565; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Chinese Spring; RA Ogihara Y., Isono K., Kojima T., Endo A., Hanaoka M., Shiina T., RA Terachi T., Utsugi S., Murata M., Mori N., Takumi S., Ikeo K., RA Gojobori T., Murai R., Murai K., Matsuoka Y., Ohnishi Y., Tajiri H., RA Tsunewaki K.; RT "Chinese spring wheat (Triticum aestivum L.) chloroplast genome: RT complete sequence and contig clones."; RL Plant Mol. Biol. Rep. 18:243-253(2000). CC -!- FUNCTION: NDH shuttles electrons from NAD(P)H:plastoquinone, via CC FMN and iron-sulfur (Fe-S) centers, to quinones in the CC photosynthetic chain and possibly in a chloroplast respiratory CC chain. The immediate electron acceptor for the enzyme in this CC species is believed to be plastoquinone. Couples the redox CC reaction to proton translocation, and thus conserves the redox CC energy in a proton gradient. {ECO:0000255|HAMAP-Rule:MF_01350}. CC -!- CATALYTIC ACTIVITY: CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol CC + n H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA- CC COMP:9561, Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, CC ChEBI:CHEBI:17757, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, CC ChEBI:CHEBI:62192; Evidence={ECO:0000255|HAMAP-Rule:MF_01350}; CC -!- CATALYTIC ACTIVITY: CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol CC + n H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA- CC COMP:9561, Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, CC ChEBI:CHEBI:17757, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, CC ChEBI:CHEBI:62192; Evidence={ECO:0000255|HAMAP-Rule:MF_01350}; CC -!- SUBUNIT: NDH is composed of at least 16 different subunits, 5 of CC which are encoded in the nucleus. {ECO:0000255|HAMAP- CC Rule:MF_01350}. CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane CC {ECO:0000255|HAMAP-Rule:MF_01350}; Multi-pass membrane protein CC {ECO:0000255|HAMAP-Rule:MF_01350}. CC -!- RNA EDITING: Modified_positions=158 {ECO:0000250}, 188 CC {ECO:0000250}, 357 {ECO:0000250}; CC -!- SIMILARITY: Belongs to the complex I subunit 1 family. CC {ECO:0000255|HAMAP-Rule:MF_01350}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB042240; BAB47090.1; -; Genomic_DNA. DR RefSeq; NP_114313.1; NC_002762.1. DR STRING; 4565.Traes_5AL_FFD2F60A3.1; -. DR PRIDE; Q95H43; -. DR GeneID; 803191; -. DR Proteomes; UP000019116; Chloroplast. DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IEA:UniProtKB-UniRule. DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW. DR GO; GO:0009060; P:aerobic respiration; IBA:GO_Central. DR GO; GO:0019684; P:photosynthesis, light reaction; IEA:UniProtKB-UniRule. DR HAMAP; MF_01350; NDH1_NuoH; 1. DR InterPro; IPR001694; NADH_UbQ_OxRdtase_su1/FPO. DR InterPro; IPR018086; NADH_UbQ_OxRdtase_su1_CS. DR PANTHER; PTHR11432; PTHR11432; 1. DR Pfam; PF00146; NADHdh; 1. DR PROSITE; PS00667; COMPLEX1_ND1_1; 1. DR PROSITE; PS00668; COMPLEX1_ND1_2; 1. PE 3: Inferred from homology; KW Chloroplast; Complete proteome; Membrane; NAD; NADP; Plastid; KW Plastoquinone; Quinone; Reference proteome; RNA editing; Thylakoid; KW Translocase; Transmembrane; Transmembrane helix. FT CHAIN 1 362 NAD(P)H-quinone oxidoreductase subunit 1, FT chloroplastic. FT /FTId=PRO_0000117517. FT TRANSMEM 29 49 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01350}. FT TRANSMEM 103 123 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01350}. FT TRANSMEM 128 148 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01350}. FT TRANSMEM 164 184 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01350}. FT TRANSMEM 202 222 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01350}. FT TRANSMEM 247 267 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01350}. FT TRANSMEM 303 323 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01350}. FT TRANSMEM 335 355 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01350}. SQ SEQUENCE 362 AA; 40438 MW; ED5FBCBED86D900B CRC64; MIIDRVEVET INSFWKLELL KEVYGLISIL PILTLLLGIT IEVLVIVWLE REISASIQQR IGPEYAGPLG LLQAIADGTK LLFKEDILPS RGDISLFSIG PSIAVISVLL SFLVIPLGYH FVLADLSIGV FLWIAISSIA PIGLLMAGYS SNNKYSFLGG LRAAAQSISY EIPLTFCVLA ISLLSNSLST VDIVEAQSKY GFFGWNIWRQ PIGFLVFLIS SLAECERLPF DLPEAEEELV AGYQTEYSGI KYGLFYLVSY LNLLVSSLFV TVLYLGGWNL SIPYISFFDF FQMNKAVGIL EMTMGIFITL TKAYLFLFIS ITIRWTLPRM RMDQLLNLGW KFLLPISLGN LLLTTSFQLV SL //