ID ATP6_POLOR STANDARD; PRT; 227 AA. AC Q95913; DT 01-NOV-1997 (Rel. 35, Created) DT 01-NOV-1997 (Rel. 35, Last sequence update) DT 16-OCT-2001 (Rel. 40, Last annotation update) DE ATP synthase A chain (EC 3.6.3.14) (Protein 6). GN MTATP6 OR ATP6. OS Polypterus ornatipinnis (Bichir). OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Chondrostei; Polypteriformes; Polypteridae; OC Polypterus. OX NCBI_TaxID=49895; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=97070832; PubMed=8913758; RA Noack K., Zardoya R., Meyer A.; RT "The complete mitochondrial DNA sequence of the bichir (Polypterus RT ornatipinnis), a basal ray-finned fish: ancient establishment of the RT consensus vertebrate gene order."; RL Genetics 144:1165-1180(1996). CC -!- FUNCTION: KEY COMPONENT OF THE PROTON CHANNEL; IT MAY PLAY A CC DIRECT ROLE IN THE TRANSLOCATION OF PROTONS ACROSS THE MEMBRANE. CC -!- SUBUNIT: F-TYPE ATPASES HAVE 2 COMPONENTS, CF(1) - THE CATALYTIC CC CORE - AND CF(0) - THE MEMBRANE PROTON CHANNEL. CF(1) HAS FIVE CC SUBUNITS: ALPHA(3), BETA(3), GAMMA(1), DELTA(1), EPSILON(1). CF(0) CC HAS THREE MAIN SUBUNITS: A, B AND C. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. CC -!- SIMILARITY: BELONGS TO THE ATPASE A CHAIN FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U62532; AAC60310.1; -. DR InterPro; IPR000568; ATP_synt_A. DR Pfam; PF00119; ATP-synt_A; 1. DR PRINTS; PR00123; ATPASEA. DR PROSITE; PS00449; ATPASE_A; 1. KW Hydrogen ion transport; CF(0); Mitochondrion; Transmembrane. SQ SEQUENCE 227 AA; 25249 MW; C08D61938B918A4C CRC64; MTLSFLDQFA SQSFLGIPLI AIAILIPWML FPSPYKRWMS NRLITFQSWF IARTTNQLML PLNTGAHKWA MILTALLLFL MTLNLLGLLP YTFTPTTQLS MNMALAVPLW LATVLIGMRN QPTHSLAHLL PEGTPTPLIP ILIIIETISL FIRPLALGVR LTANLTAGHL LIQLISTATF VMLSIMPTIA TLTFIVLALL TILEIAVAMI QAYVLVLLLS LYLQENV //