ID Q957Y1_ANODD Unreviewed; 116 AA. AC Q957Y1; DT 01-DEC-2001, integrated into UniProtKB/TrEMBL. DT 01-DEC-2001, sequence version 1. DT 07-NOV-2018, entry version 70. DE RecName: Full=NADH-ubiquinone oxidoreductase chain 3 {ECO:0000256|RuleBase:RU003640, ECO:0000256|SAAS:SAAS01013638}; DE EC=1.6.5.3 {ECO:0000256|RuleBase:RU003640}; OS Anomalopteryx didiformis (Little bush moa). OG Mitochondrion {ECO:0000313|EMBL:AAK53336.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; OC Coelurosauria; Aves; Palaeognathae; Dinornithiformes; Emeidae; OC Anomalopteryx. OX NCBI_TaxID=8811 {ECO:0000313|EMBL:AAK53336.1}; RN [1] {ECO:0000313|EMBL:AAK53336.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=11370967; DOI=10.1098/rspb.2001.1587; RA Haddrath O., Baker A.J.; RT "Complete mitochondrial DNA genome sequences of extinct birds: ratite RT phylogenetics and the vicariance biogeography hypothesis."; RL Proc. R. Soc. B 268:939-945(2001). CC -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory CC chain NADH dehydrogenase (Complex I) that is believed to belong to CC the minimal assembly required for catalysis. Complex I functions CC in the transfer of electrons from NADH to the respiratory chain. CC The immediate electron acceptor for the enzyme is believed to be CC ubiquinone. {ECO:0000256|SAAS:SAAS01013641}. CC -!- CATALYTIC ACTIVITY: NADH + ubiquinone + 5 H(+)(In) = NAD(+) + CC ubiquinol + 4 H(+)(Out). {ECO:0000256|RuleBase:RU003640, CC ECO:0000256|SAAS:SAAS01013639}. CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane CC {ECO:0000256|SAAS:SAAS01013624}; Multi-pass membrane protein CC {ECO:0000256|SAAS:SAAS01013624}. CC -!- SIMILARITY: Belongs to the complex I subunit 3 family. CC {ECO:0000256|RuleBase:RU003640}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF338714; AAK53336.1; -; Genomic_DNA. DR PIR; H90622; H90622. DR RefSeq; NP_115370.1; NC_002779.1. DR GeneID; 803294; -. DR CTD; 4537; -. DR HOVERGEN; HBG017392; -. DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC. DR Gene3D; 1.20.58.1610; -; 1. DR InterPro; IPR000440; NADH_UbQ/plastoQ_OxRdtase_su3. DR InterPro; IPR038430; NDAH_ubi_oxred_su3_sf. DR PANTHER; PTHR11058; PTHR11058; 1. DR Pfam; PF00507; Oxidored_q4; 1. PE 3: Inferred from homology; KW Electron transport {ECO:0000256|SAAS:SAAS01013627}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000256|RuleBase:RU003640, KW ECO:0000256|SAAS:SAAS01013640, ECO:0000313|EMBL:AAK53336.1}; KW NAD {ECO:0000256|RuleBase:RU003640, ECO:0000256|SAAS:SAAS01013636}; KW Oxidoreductase {ECO:0000256|RuleBase:RU003640}; KW Respiratory chain {ECO:0000256|SAAS:SAAS01013630}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}; KW Transport {ECO:0000256|SAAS:SAAS01013630}; KW Ubiquinone {ECO:0000256|RuleBase:RU003640, KW ECO:0000256|SAAS:SAAS01013621}. FT TRANSMEM 52 74 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 86 105 Helical. {ECO:0000256|SAM:Phobius}. SQ SEQUENCE 116 AA; 13331 MW; 0CBD1BDBAC8B9631 CRC64; MNMVTFMLLL SFTLCTILTT INFWLAQMNP DTEKLSPYEC GFDPLGSARL PFSIRFFLMA ILFLLFDLEI ALLLPLPWAI QLPQPLLTLL WTSMILLLLT LGLAYEWMQG GLEWAE //