ID GLYK_ARATH STANDARD; PRT; 456 AA. AC Q944I4; Q8LFL2; Q9C5L9; Q9C967; DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot. DT 30-AUG-2005, sequence version 2. DT 17-OCT-2006, entry version 25. DE D-glycerate 3-kinase, chloroplast precursor (EC 2.7.1.31) (AtGLYK). GN Name=GLYK; OrderedLocusNames=At1g80380; ORFNames=F5I6.13; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; OC rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX MEDLINE=21016719; PubMed=11130712; DOI=10.1038/35048500; RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., RA White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., RA Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., RA Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., RA Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., RA Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., RA Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., RA Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., RA Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., RA Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., RA Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., RA Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., RA Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., RA Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., RA Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.; RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis RT thaliana."; RL Nature 408:816-820(2000). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=cv. Columbia; RX MEDLINE=22954850; PubMed=14593172; DOI=10.1126/science.1088305; RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., RA Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., RA Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., RA Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., RA Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., RA Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., RA Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., RA Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., RA Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., RA Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., RA Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., RA Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.; RT "Empirical analysis of transcriptional activity in the Arabidopsis RT genome."; RL Science 302:842-846(2003). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., RA Feldmann K.A.; RT "Full-length cDNA from Arabidopsis thaliana."; RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. RN [4] RP ENZYME ACTIVITY, IDENTIFICATION BY MASS SPECTROMETRY, AND FUNCTION. RX PubMed=15980259; DOI=10.1105/tpc.105.033993; RA Boldt R., Edner C., Kolukisaoglu U., Hagemann M., Weckwerth W., RA Wienkoop S., Morgenthal K., Bauwe H.; RT "D-glycerate 3-kinase, the last unknown enzyme in the photorespiratory RT cycle in Arabidopsis, belongs to a novel kinase family."; RL Plant Cell 17:2413-2420(2005). CC -!- FUNCTION: Catalyzes the concluding reaction of the CC photorespiratory C2 cycle, an indispensable ancillary metabolic CC pathway to the photosynthetic C3 cycle that enables land plants to CC grow in an oxygen-containing atmosphere. CC -!- CATALYTIC ACTIVITY: ATP + (R)-glycerate = ADP + 3-phospho-(R)- CC glycerate. CC -!- PATHWAY: Photorespiratory pathway (glycolate pathway). CC -!- SUBCELLULAR LOCATION: Plastid; chloroplast. CC -!- ALTERNATIVE PRODUCTS: CC Event=Alternative splicing; Named isoforms=2; CC Name=1; CC IsoId=Q944I4-1; Sequence=Displayed; CC Name=2; CC IsoId=Q944I4-2; Sequence=VSP_015208; CC Note=No experimental confirmation available; CC -!- SIMILARITY: Belongs to the GLYK kinase family. CC -!- CAUTION: Ref.1 sequence differs from that shown due to erroneous CC gene model prediction. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC018848; AAG52441.1; ALT_SEQ; Genomic_DNA. DR EMBL; AF360156; AAK25866.1; -; mRNA. DR EMBL; AF428401; AAL16169.1; -; mRNA. DR EMBL; AY056310; AAL07159.1; -; mRNA. DR EMBL; AY084779; AAM61346.1; -; mRNA. DR PIR; E96835; E96835. DR UniGene; At.24938; -. DR HSSP; P42938; 1ODF. DR GenomeReviews; CT485782_GR; AT1G80380. DR KEGG; ath:At1g80380; -. DR TAIR; At1g80380; -. KW Alternative splicing; ATP-binding; Chloroplast; Glycolate pathway; KW Kinase; Nucleotide-binding; Photorespiration; Plastid; Transferase; KW Transit peptide. FT TRANSIT 1 ? Chloroplast (Potential). FT CHAIN ? 456 D-glycerate 3-kinase. FT /FTId=PRO_0000012282. FT NP_BIND 215 222 ATP (Potential). FT VAR_SEQ 206 299 Missing (in isoform 2). FT /FTId=VSP_015208. FT CONFLICT 188 188 W -> C (in Ref. 3). FT CONFLICT 239 239 S -> P (in Ref. 2; AAL16169). SQ SEQUENCE 456 AA; 51018 MW; 5961E0FC6E2220FB CRC64; MAVAISGSSL ISSTLQHYNN RIYIRDYPIP CHSSNPICNS FNFKRRSFSP SSPKFNDHVV NPSSSYLSSK LSPIRTHSSF AACGCSWIQD NSMVHDYATT TNGTSKRCSA LPTTNTVDVS SVSDLFEFIC SGPLVNKIGI TPQRVGQSID KWLLYGSQLC RLFQLNELKL TIPQKARLYH YYIPVFIWCE DQIALHNSKF KDGDDVPPLV IGFSAPQGCG KTTLVFALDY LFKTTKKKSA TISVDDFYLT AEGQAELRKK NPGNALLEYR GNAGSHDLKL SVETLEALSK LTKEGLKMKV PRYNKSAYSG RGDRADSSTW PEVEGPLSVI LFEGWMLGFK PLPADVVKAV DPQLEVVNKN LEAYYDAWDK YIDAWVVIKI QDPSYVYRWR LQAEIAMRQD GQAGMSDEEV NDFVSRYLPA YKAYLPTLYA EGPSGSDPDR VLAIDIDEER NPILAN //