ID Q93VJ2_ARATH Unreviewed; 881 AA. AC Q93VJ2; DT 01-DEC-2001, integrated into UniProtKB/TrEMBL. DT 01-DEC-2001, sequence version 1. DT 25-JAN-2012, entry version 72. DE SubName: Full=AT5g24360/K16H17_7; DE SubName: Full=Endoribonuclease/protein kinase Ire1p-like protein; DE SubName: Full=Protein inositol requiring 1-1; GN Name=IRE1b; Synonyms=IRE1-1; OrderedLocusNames=At5g24360; GN ORFNames=AT5G24360; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX MEDLINE=21016721; PubMed=11130714; DOI=10.1038/35048507; RG Kazusa DNA Research Institute; RG Cold Spring Harbor and Washington University in St Louis Sequencing RG Consortium; RG European Union Arabidopsis Genome Sequencing Consortium; RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., RA Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., RA Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T., RA Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., RA Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., RA Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., RA Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., RA Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., RA Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., RA Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., RA Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., RA Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., RA Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., RA Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., RA van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., RA Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., RA Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., RA Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., RA Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.; RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis RT thaliana."; RL Nature 408:823-826(2000). RN [2] RP NUCLEOTIDE SEQUENCE. RA Cheuk R., Chen H., Kim C.J., Koesema E., Meyers M.C., Banh J., RA Bowser L., Carninci P., Dale J.M., Goldsmith A.D., Hayashizaki Y., RA Ishida J., Jiang P.X., Jones T., Kamiya A., Karlin-Neumann G., RA Kawai J., Lam B., Lee J.M., Lin J., Liu S.X., Miranda M., Narusaka M., RA Nguyen M., Onodera C.S., Palm C.J., Pham P.K., Quach H.L., Sakurai T., RA Satou M., Seki M., Southwick A., Tang C.C., Toriumi M., Yamada K., RA Yamamura Y., Yu G., Yu S., Shinozaki K., Davis R.W., Theologis A., RA Ecker J.R.; RT "Arabidopsis cDNA clones."; RL Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RA Noh S.-J., Oh C.-S., Chung W.-I.; RT "Characterization of two homologs of Ire1p, a kinase/endoribonuclease, RT in Arabidopsis thaliana."; RL Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RG The Arabidopsis Information Resource (TAIR); RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY057480; AAL09714.1; -; mRNA. DR EMBL; AY057897; AAL17714.1; -; mRNA. DR EMBL; CP002688; AED93301.1; -; Genomic_DNA. DR IPI; IPI01020052; -. DR RefSeq; NP_568444.1; NM_122344.4. DR UniGene; At.26226; -. DR ProteinModelPortal; Q93VJ2; -. DR SMR; Q93VJ2; 451-879. DR STRING; Q93VJ2; -. DR PRIDE; Q93VJ2; -. DR EnsemblPlants; AT5G24360.1; AT5G24360.1; AT5G24360. DR GeneID; 832507; -. DR KEGG; ath:AT5G24360; -. DR NMPDR; fig|3702.1.peg.24628; -. DR TAIR; At5g24360; -. DR InParanoid; Q93VJ2; -. DR OMA; GKHPYGD; -. DR PhylomeDB; Q93VJ2; -. DR ProtClustDB; CLSN2917705; -. DR Genevestigator; Q93VJ2; -. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IGI:TAIR. DR GO; GO:0006397; P:mRNA processing; IEA:InterPro. DR GO; GO:0000394; P:RNA splicing, via endonucleolytic cleavage and ligation; IDA:TAIR. DR InterPro; IPR010513; KEN_RNase_activator. DR InterPro; IPR011009; Kinase-like_dom. DR InterPro; IPR018391; PQQ_beta_propeller_repeat. DR InterPro; IPR000719; Prot_kinase_cat_dom. DR InterPro; IPR006567; PUG-dom. DR InterPro; IPR011047; Quinonprotein_ADH-like. DR InterPro; IPR017442; Se/Thr_kinase-like_dom. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR Gene3D; G3DSA:2.140.10.10; Quinoprotein_alc_DH-like; 1. DR Pfam; PF00069; Pkinase; 1. DR Pfam; PF06479; Ribonuc_2-5A; 1. DR SMART; SM00564; PQQ; 2. DR SMART; SM00580; PUG; 1. DR SUPFAM; SSF56112; Kinase_like; 1. DR SUPFAM; SSF50998; Quin_alc_DH_like; 1. DR PROSITE; PS51392; KEN; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 2: Evidence at transcript level; KW Complete proteome; Kinase; Reference proteome. SQ SEQUENCE 881 AA; 99616 MW; AECD3585336081F8 CRC64; MRGSALLDLI LFLLVSPLAH SFKGSEISKF YDKSISNQIS QSDRESGYVL VSTVDGSISL VDMSSQKLDW TFHTNEPIYS SYQAPHYHYT TDEERSSVLG DDFYMDCDKD WRLYNSSVRK GKRVNEIVDA SEFIGTLPYT STDRIVLGKK DTSVFLLDWK TGKLVKRYRM DELYSNTVVE NDKEKAIVLS KEAPLLFGSG FKKSEDFPEL VYIERKDFKI QCISKFGDVL WSVSYAKMEA KLQNHESVQF ISGLSSSVGK NQFPLSYTTS VPMVQLRNVK YETLFPRLGF LDEALYLPFQ DRKPNQLAIG DGNQLTLPGN KEAEEVLSLP LPETVISQIT DIIDGSTKQA GFASKFSGLI VLIFGFCVTM LSVCGLFFYR LRQSIRIKEP YVSEVPIATP KKKKSKKNGT TKAVHKKENG FISGGNKDPS HEENEKRLLT AFPGLNNSSA EGYRVGKLFV SNKEIAKGSN GTVVLEGSYE GRLVAVKRLV QSHHDVAQKE ILNLMASDKH SNIVRWYGVD QDEHFIYISL ELCACSLNDL IYASSALLES PMASSSIHSI QINPIFENGK GVELWKENGH PSPVLLKLMR DIVAGLVHLH DIGIVHRDLK PQNVLIVKNS SLCAKLSDMG ISKRLPADTS ALTRNSTGLG SGSSGWQAPE QLRNERQTRA VDLFSLGCVL FFCMTGGKHP YGDNYERDVN VLNDQKDLFL IESLPEAVHL LTGLLNPDPN LRPRAQDVMH HPLFWNSDMR LSFLRDASDR VELENREEGS QLLAALESTA AVTLNGRWDE KLDSIFLDNI GRYRRYKFDS IRDLLRVIRN KLNHYRELPK ELQELLGSVP EGFERYFSSR FPKLLIQVYT VLFDYCNNEE FFFKYSKTTV F //