ID CCMA_RICCN STANDARD; PRT; 191 AA. AC Q92G95; DT 15-JUN-2004 (Rel. 44, Created) DT 15-JUN-2004 (Rel. 44, Last sequence update) DT 15-JUN-2004 (Rel. 44, Last annotation update) DE Cytochrome c biogenesis ATP-binding export protein ccmA (EC 3.6.3.41) DE (Heme exporter protein A). GN CCMA OR RC1228. OS Rickettsia conorii. OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; OC Rickettsiaceae; Rickettsieae; Rickettsia. OX NCBI_TaxID=781; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=Malish 7; RX MEDLINE=21442074; PubMed=11557893; RA Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., RA Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., RA Raoult D.; RT "Mechanisms of evolution in Rickettsia conorii and R. prowazekii."; RL Science 293:2093-2098(2001). CC -!- FUNCTION: Part of the ABC transporter complex ccmAB involved in CC the biogenesis of c-type cytochromes; once thought to export heme, CC this seems not to be the case, but its exact role is uncertain. CC Responsible for energy coupling to the transport system (By CC similarity). CC -!- CATALYTIC ACTIVITY: ATP + H(2)O + heme(In) = ADP + phosphate + CC heme(Out). CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins CC (ccmA) and two transmembrane proteins (ccmB) (Probable). CC -!- SUBCELLULAR LOCATION: Inner membrane-associated (By similarity). CC -!- SIMILARITY: Belongs to the ABC transporter family. CcmA exporter CC (TC 3.A.1.107) subfamily. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE008670; AAL03766.1; ALT_INIT. DR PIR; D97853; D97853. DR InterPro; IPR003593; AAA_ATPase. DR InterPro; IPR003439; ABC_transporter. DR Pfam; PF00005; ABC_tran; 1. DR SMART; SM00382; AAA; 1. DR PROSITE; PS00211; ABC_TRANSPORTER_1; FALSE_NEG. DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1. KW Hydrolase; Transport; Cytochrome c-type biogenesis; Membrane; KW Inner membrane; ATP-binding; Complete proteome. FT NP_BIND 57 64 ATP (By similarity). SQ SEQUENCE 191 AA; 21427 MW; D8C69C94FDB9AAB8 CRC64; MLSLHQLQFK NLFDLNITFL PSSITYIKGA NGCGKSSLLR MIAGIMQPSS GHIYYRNCNI NNIAKLYCTY IGHNLGLKSE MTVFENLKFW SEIYNSAATV YAAIHYFKLH DLLDKKCYSL SSGMQKIVAI ARLIACQSDL WLLDEVETNL SKENRALLNN LIVMKANSGG IVLLSSHLES SIKSAQILRI D //