ID TM9S4_HUMAN Reviewed; 625 AA. AC Q92544; Q9NUA3; DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1997, sequence version 1. DT 04-DEC-2007, entry version 56. DE Transmembrane 9 superfamily member 4. GN Name=TM9SF4; Synonyms=KIAA0255; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Bone marrow; RX MEDLINE=97191544; PubMed=9039502; DOI=10.1093/dnares/3.5.321; RA Nagase T., Seki N., Ishikawa K., Ohira M., Kawarabayasi Y., Ohara O., RA Tanaka A., Kotani H., Miyajima N., Nomura N.; RT "Prediction of the coding sequences of unidentified human genes. VI. RT The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by RT analysis of cDNA clones from cell line KG-1 and brain."; RL DNA Res. 3:321-329(1996). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX MEDLINE=21638749; PubMed=11780052; DOI=10.1038/414865a; RA Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., RA Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., RA Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., RA Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., RA Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., RA Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., RA Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., RA Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., RA Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., RA Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., RA Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., RA Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., RA Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., RA Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., RA Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., RA Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., RA Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., RA Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., RA Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., RA Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., RA Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., RA Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., RA Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., RA Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., RA Rogers J.; RT "The DNA sequence and comparative analysis of human chromosome 20."; RL Nature 414:865-871(2001). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Brain, and Muscle; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein CC (Probable). CC -!- SIMILARITY: Belongs to the nonaspanin (TM9SF) family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; D87444; BAA13385.2; ALT_INIT; mRNA. DR EMBL; AL049539; CAB75607.2; -; Genomic_DNA. DR EMBL; BC021107; AAH21107.1; -; mRNA. DR EMBL; BC022850; AAH22850.1; -; mRNA. DR RefSeq; NP_055557.1; -. DR UniGene; Hs.654665; -. DR PeptideAtlas; Q92544; -. DR Ensembl; ENSG00000101337; Homo sapiens. DR GeneID; 9777; -. DR KEGG; hsa:9777; -. DR HGNC; HGNC:30797; TM9SF4. DR PharmGKB; PA134937613; -. DR ArrayExpress; Q92544; -. DR CleanEx; HS_TM9SF4; -. DR GermOnline; ENSG00000101337; Homo sapiens. DR InterPro; IPR004240; EMP70. DR PANTHER; PTHR10766; EMP70; 1. DR Pfam; PF02990; EMP70; 1. PE 1: Evidence at protein level; KW Membrane; Transmembrane. FT CHAIN 1 625 Transmembrane 9 superfamily member 4. FT /FTId=PRO_0000210178. FT TRANSMEM 265 285 Potential. FT TRANSMEM 330 350 Potential. FT TRANSMEM 360 380 Potential. FT TRANSMEM 400 420 Potential. FT TRANSMEM 433 453 Potential. FT TRANSMEM 485 505 Potential. FT TRANSMEM 519 539 Potential. FT TRANSMEM 554 574 Potential. FT TRANSMEM 582 602 Potential. SQ SEQUENCE 625 AA; 72541 MW; 69460C8C7E2EEEF5 CRC64; MCETSAFYVP GVAPINFHQN DPVEIKAVKL TSSRTQLPYE YYSLPFCQPS KITYKAENLG EVLRGDRIVN TPFQVLMNSE KKCEVLCSQS NKPVTLTVEQ SRLVAERITE DYYVHLIADN LPVATRLELY SNRDSDDKKK EKDVQFEHGY RLGFTDVNKI YLHNHLSFIL YYHREDMEED QEHTYRVVRF EVIPQSIRLE DLKADEKSSC TLPEGTNSSP QEIDPTKENQ LYFTYSVHWE ESDIKWASRW DTYLTMSDVQ IHWFSIINSV VVVFFLSGIL SMIIIRTLRK DIANYNKEDD IEDTMEESGW KLVHGDVFRP PQYPMILSSL LGSGIQLFCM ILIVIFVAML GMLSPSSRGA LMTTACFLFM FMGVFGGFSA GRLYRTLKGH RWKKGAFCTA TLYPGVVFGI CFVLNCFIWG KHSSGAVPFP TMVALLCMWF GISLPLVYLG YYFGFRKQPY DNPVRTNQIP RQIPEQRWYM NRFVGILMAG ILPFGAMFIE LFFIFSAIWE NQFYYLFGFL FLVFIILVVS CSQISIVMVY FQLCAEDYRW WWRNFLVSGG SAFYVLVYAI FYFVNKLDIV EFIPSLLYFG YTALMVLSFW LLTGTIGFYA AYMFVRKIYA AVKID //