ID Q91YH6_MOUSE Unreviewed; 513 AA. AC Q91YH6; DT 01-DEC-2001, integrated into UniProtKB/TrEMBL. DT 01-DEC-2001, sequence version 1. DT 08-APR-2008, entry version 59. DE ATPase, H+ transporting, lysosomal V1 subunit B1 (17 days embryo DE kidney cDNA, RIKEN full-length enriched library, clone:I920069L07 DE product:ATPase, H+ transporting, V1 subunit B, isoform 1, full insert DE sequence) (16 days embryo lung cDNA, RIKEN full-length enriched DE library, clone:8430420B20 product:SIMILAR TO ATPASE, H+ TRANSPORTING, DE LYSOSOMAL (VACUOLAR PROTON PUMP), BETA POLYPEPTIDE, 56/58KD, ISOFORM 1 DE (RENAL TUBULAR ACIDOSIS WITH DEAFNESS) homolog) (0 day neonate kidney DE cDNA, RIKEN full-length enriched library, clone:D630033H02 DE product:SIMILAR TO ATPASE, H+ TRANSPORTING, LYSOSOMAL (VACUOLAR PROTON DE PUMP), BETA POLYPEPTIDE, 56/58KD, ISOFORM 1 (RENAL TUBULAR ACIDOSIS DE WITH DEAFNESS) homolog) (0 day neonate kidney cDNA, RIKEN full-length DE enriched library, clone:D630003L15 product:ATPASE, H+ TRANSPORTING, DE LYSOSOMAL (VACUOLAR PROTON PUMP), BETA POLYPEPTIDE, 56/58KD, ISOFORM 1 DE (RENAL TUBULAR ACIDOSIS WITH DEAFNESS) homolog) (Vacuolar proton DE translocating ATPase B1 isoform). GN Name=Atp6v1b1; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=FVB/N; TISSUE=Mammary tumor. Metallothionien-TGF alpha model. RC 10 month old virgin mouse. Taken by biopsy.; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=C57BL/6J; TISSUE=Kidney, and Lung; RX PubMed=16141072; DOI=10.1126/science.1112014; RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., RA Davis M.J., Wilming L.G., Aidinis V., Allen J.E., RA Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., RA Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., RA Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., RA Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., RA di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., RA Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., RA Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., RA Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., RA Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., RA Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., RA Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., RA Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., RA Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., RA Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., RA Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., RA Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., RA Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., RA Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., RA Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., RA Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., RA Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., RA Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., RA Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., RA Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., RA Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., RA Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., RA Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., RA Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., RA Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., RA Hayashizaki Y.; RT "The transcriptional landscape of the mammalian genome."; RL Science 309:1559-1563(2005). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL; TISSUE=Kidney; RA Nishi T., Forgac M.; RT "Interaction of the a and B subunit isoforms of the mouse vacuolar RT proton translocating ATPase."; RL Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the ATPase alpha/beta chains family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC017127; AAH17127.1; -; mRNA. DR EMBL; AF435091; AAN45856.1; -; mRNA. DR EMBL; AK052604; BAC35059.1; -; mRNA. DR EMBL; AK052707; BAC35108.1; -; mRNA. DR EMBL; AK078810; BAC37404.1; -; mRNA. DR EMBL; AK168980; BAE40781.1; -; mRNA. DR RefSeq; NP_598918.1; -. DR UniGene; Mm.220823; -. DR Ensembl; ENSMUSG00000006269; Mus musculus. DR GeneID; 110935; -. DR KEGG; mmu:110935; -. DR MGI; MGI:103285; Atp6v1b1. DR ArrayExpress; Q91YH6; -. DR GO; GO:0016324; C:apical plasma membrane; IDA:MGI. DR GO; GO:0016323; C:basolateral plasma membrane; IDA:MGI. DR GO; GO:0005624; C:membrane fraction; IDA:MGI. DR GO; GO:0015078; F:hydrogen ion transmembrane transporter acti...; IMP:MGI. DR GO; GO:0006885; P:regulation of pH; IMP:MGI. DR InterPro; IPR000793; ATPase_a_b_C. DR InterPro; IPR004100; ATPase_a_b_N. DR InterPro; IPR000194; ATPase_a_b_nl_bd. DR InterPro; IPR005723; ATPase_V1_B. DR Pfam; PF00006; ATP-synt_ab; 1. DR Pfam; PF00306; ATP-synt_ab_C; 1. DR Pfam; PF02874; ATP-synt_ab_N; 1. DR TIGRFAMs; TIGR01040; V-ATPase_V1_B; 1. DR PROSITE; PS00152; ATPASE_ALPHA_BETA; 1. PE 2: Evidence at transcript level; KW Hydrogen ion transport; Ion transport; Transport. SQ SEQUENCE 513 AA; 56791 MW; 43EE1D236D4F6406 CRC64; MATTVDSRSS GFTGNSCDPG TAQEHVQAVT RNYITHPRVT YRTVCSVNGP LVVLDQVKFA QYAEIVNFTL PDGTQRSGQV LEVAGTKAIV QVFEGTSGID SQKTTCEFTG DILRTPVSED MLGRIFNGSG KPIDKGPAVM AEEFLDINGQ PINPHDRIYP EEMIQTGISP IDVMNSIARG QKIPIFSAAG LPHNEIAAQI CRQAGLVKKS KAVLDYHEDN FAIVFAAMGV NMETARFFKS DFEQNGTMGN VCLFLNLAND PTIERIITPR LALTTAEFLA YQCEKHVLVI LTDMSSYAEA LREVSAAREE VPGRRGFPGY MYTDLATIYE RAGRVEGRGG SITQIPILTM PNDDITHPIP DLTGFITEGQ IYVDRQLHNR QVYPPINVLP SLSRLMKSAI GEGMTRKDHG DVSNQLYACY AIGKDVQAMK AVVGEEALTS EDLLYLEFLQ KFEKNFITQG PYENRTVFES LDLGWKLLRI FPKEMLKRIP QSMTDEFYSR QGAQQDPASD TAL //