ID Q91VB8_MOUSE PRELIMINARY; PRT; 142 AA. AC Q91VB8; DT 01-DEC-2001 (TrEMBLrel. 19, Created) DT 01-DEC-2001 (TrEMBLrel. 19, Last sequence update) DT 10-MAY-2005 (TrEMBLrel. 30, Last annotation update) DE Mus musculus 13 days embryo liver cDNA, RIKEN full-length enriched DE library, clone:2500002C06 product:hemoglobin, beta adult major chain, DE full insert sequence (Hemoglobin alpha, adult chain 1) (Mus musculus DE adult male spleen cDNA, RIKEN full-length enriched library, DE clone:0910001I20 product:hemoglobin alpha, adult chain 1, full insert DE sequence) (Mus musculus adult female placenta cDNA, RIKEN full-length DE enriched library, clone:1600012O02 product:hemoglobin, beta adult DE major chain, full insert sequence) (Mus musculus 13 days embryo liver DE cDNA, RIKEN full-length enriched library, clone:2510006N19 DE product:hemoglobin, beta adult major chain, full insert sequence) (Mus DE musculus 13 days embryo liver cDNA, RIKEN full-length enriched DE library, clone:2510008C04 product:hemoglobin, beta adult major chain, DE full insert sequence) (Mus musculus 13 days embryo liver cDNA, RIKEN DE full-length enriched library, clone:2510008I03 product:hemoglobin, DE beta adult major chain, full insert sequence) (Mus musculus 13 days DE embryo liver cDNA, RIKEN full-length enriched library, DE clone:2510008N05 product:hemoglobin, beta adult major chain, full DE insert sequence) (Mus musculus 13 days embryo liver cDNA, RIKEN full- DE length enriched library, clone:2510019L20 product:hemoglobin, beta DE adult major chain, full insert sequence) (Mus musculus 13 days embryo DE liver cDNA, RIKEN full-length enriched library, clone:2510028L03 DE product:hemoglobin, beta adult major chain, full insert sequence) (Mus DE musculus 13 days embryo liver cDNA, RIKEN full-length enriched DE library, clone:2510029I10 product:hemoglobin, beta adult major chain, DE full insert sequence) (Mus musculus 13 days embryo liver cDNA, RIKEN DE full-length enriched library, clone:2510029K11 product:hemoglobin, DE beta adult major chain, full insert sequence) (Mus musculus 13 days DE embryo liver cDNA, RIKEN full-length enriched library, DE clone:2510029N07 product:hemoglobin, beta adult major chain, full DE insert sequence) (Mus musculus 13 days embryo liver cDNA, RIKEN full- DE length enriched library, clone:2510030E10 product:hemoglobin, beta DE adult major chain, full insert sequence) (Mus musculus 13 days embryo DE liver cDNA, RIKEN full-length enriched library, clone:2510039E24 DE product:hemoglobin, beta adult major chain, full insert sequence) (Mus DE musculus 13 days embryo liver cDNA, RIKEN full-length enriched DE library, clone:2510040M14 product:hemoglobin, beta adult major chain, DE full insert sequence) (Mus musculus 13 days embryo liver cDNA, RIKEN DE full-length enriched library, clone:2510049K03 product:hemoglobin, DE beta adult major chain, full insert sequence) (Mus musculus 11 days DE embryo whole body cDNA, RIKEN full-length enriched library, DE clone:2700038D19 product:hemoglobin, beta adult major chain, full DE insert sequence) (Mus musculus 11 days embryo whole body cDNA, RIKEN DE full-length enriched library, clone:2700038O11 product:hemoglobin, DE beta adult major chain, full insert sequence) (Mus musculus 10, 11 DE days embryo whole body cDNA, RIKEN full-length enriched library, DE clone:2810017J06 product:hemoglobin, beta adult major chain, full DE insert sequence) (Mus musculus 13 days embryo liver cDNA, RIKEN full- DE length enriched library, clone:2510047K14 product:hemoglobin, beta DE adult major chain, full insert sequence) (Alpha globin 1) (Alpha DE globin 2). GN Name=Hba-a1; Synonyms=haemaglobin alpha 1, haemaglobin alpha 2; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Liver, Placenta, Spleen, and Whole body; RX MEDLINE=99279253; PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9; RA Carninci P., Hayashizaki Y.; RT "High-efficiency full-length cDNA cloning."; RL Meth. Enzymol. 303:19-44(1999). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Liver, Placenta, Spleen, and Whole body; RX MEDLINE=21085660; PubMed=11217851; DOI=10.1038/35055500; RA RIKEN FANTOM Consortium; RT "Functional annotation of a full-length mouse cDNA collection."; RL Nature 409:685-690(2001). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Liver, Placenta, Spleen, and Whole body; RX MEDLINE=22354683; PubMed=12466851; DOI=10.1038/nature01266; RA The FANTOM Consortium, RA the RIKEN Genome Exploration Research Group Phase I & II Team; RT "Analysis of the mouse transcriptome based on functional annotation of RT 60,770 full-length cDNAs."; RL Nature 420:563-573(2002). RN [4] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Liver, Placenta, Spleen, and Whole body; RX MEDLINE=20499374; PubMed=11042159; DOI=10.1101/gr.145100; RA Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., RA Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.; RT "Normalization and subtraction of cap-trapper-selected cDNAs to RT prepare full-length cDNA libraries for rapid discovery of new genes."; RL Genome Res. 10:1617-1630(2000). RN [5] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Liver, Placenta, Spleen, and Whole body; RX MEDLINE=20530913; PubMed=11076861; DOI=10.1101/gr.152600; RA Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., RA Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., RA Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A., RA Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., RA Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., RA Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., RA Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.; RT "RIKEN integrated sequence analysis (RISA) system-384-format RT sequencing pipeline with 384 multicapillary sequencer."; RL Genome Res. 10:1757-1771(2000). RN [6] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Liver; RA Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., RA Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., RA Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F., RA Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., RA Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., RA Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., RA Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., RA Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., RA Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., RA Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., RA Muramatsu M., Hayashizaki Y.; RL Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. RN [7] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6; TISSUE=Brain; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RG Mammalian Gene Collection Program Team; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., RA Krzywinski M.I., Skalska U., Smailus D.E., Schnerch A., Schein J.E., RA Jones S.J., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). RN [8] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6; TISSUE=Brain; RA Strausberg R.; RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. RN [9] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Liver, Placenta, Spleen, and Whole body; RA Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., RA Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., RA Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F., RA Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., RA Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., RA Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., RA Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., RA Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., RA Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., RA Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., RA Muramatsu M., Hayashizaki Y.; RL Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. RN [10] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Liver; RA Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., RA Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., RA Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., RA Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T., RA Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., RA Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., RA Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., RA Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., RA Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., RA Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., RA Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; RL Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. RN [11] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=21096913; PubMed=11157800; DOI=10.1093/hmg/10.4.371; RA Flint J., Tufarelli C., Peden J., Clark K., Daniels R.J., Hardison R., RA Miller W., Philipsen S., Tan-Un K.C., McMorrow T., Frampton J., RA Alter B.P., Frischauf A.M., Higgs D.R.; RT "Comparative genome analysis delimits a chromosomal domain and RT identifies key regulatory elements in the alpha globin cluster."; RL Hum. Mol. Genet. 10:371-382(2001). CC -!- FUNCTION: Involved in oxygen transport from the lung to the CC various peripheral tissues (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK019138; BAB31564.1; -; mRNA. DR EMBL; BC043020; AAH43020.1; -; mRNA. DR EMBL; AK003077; BAB22552.1; -; mRNA. DR EMBL; AK005434; BAB24028.1; -; mRNA. DR EMBL; AK010923; BAB27269.1; -; mRNA. DR EMBL; AK010927; BAB27272.1; -; mRNA. DR EMBL; AK010933; BAB27277.1; -; mRNA. DR EMBL; AK010937; BAB27279.1; -; mRNA. DR EMBL; AK010987; BAB27307.1; -; mRNA. DR EMBL; AK011018; BAB27336.1; -; mRNA. DR EMBL; AK011023; BAB27340.1; -; mRNA. DR EMBL; AK011025; BAB27342.1; -; mRNA. DR EMBL; AK011028; BAB27344.1; -; mRNA. DR EMBL; AK011030; BAB27346.1; -; mRNA. DR EMBL; AK011055; BAB27364.1; -; mRNA. DR EMBL; AK011073; BAB27378.1; -; mRNA. DR EMBL; AK011121; BAB27414.1; -; mRNA. DR EMBL; AK012329; BAB28166.1; -; mRNA. DR EMBL; AK012348; BAB28179.1; -; mRNA. DR EMBL; AK012755; BAB28446.1; -; mRNA. DR EMBL; AK028173; BAC25790.1; -; mRNA. DR EMBL; AY016021; AAL32371.1; -; Genomic_DNA. DR EMBL; AY016021; AAL32372.1; -; Genomic_DNA. DR HSSP; P01922; 1BZ1. DR SMR; Q91VB8; 1-142. DR MGI; MGI:96015; Hba-a1. DR GO; GO:0005739; C:mitochondrion; IDA. DR InterPro; IPR002338; Alpha_haem. DR InterPro; IPR000971; Globin. DR InterPro; IPR012292; Globin_related. DR InterPro; IPR002339; Pi_haem. DR Pfam; PF00042; Globin; 1. DR PRINTS; PR00612; ALPHAHAEM. DR PRINTS; PR00815; PIHAEM. DR PROSITE; PS01033; GLOBIN; 1. KW Heme; Iron; Metal-binding; Oxygen transport; Transport. SQ SEQUENCE 142 AA; 15112 MW; 2F6A3712E555CB4A CRC64; MVLSGEDKSN IKAAWGKIGG HGAEYGAEAL ERMFASFPTT KTYFPHFDVS HGSAQVKGHG KKVADALANA AGHLDDLPGA LSALSDLHAH KLRVDPVNFK LLSHCLLVTL ASHHPADFTP AVHASLDKFL ASVSTVLTSK YR //