ID GVPA_NOSS1 Reviewed; 71 AA. AC Q8XFU1; DT 02-AUG-2002, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 3. DT 13-SEP-2023, entry version 90. DE RecName: Full=Gas vesicle protein A {ECO:0000255|HAMAP-Rule:MF_00576}; DE Short=GvpA {ECO:0000255|HAMAP-Rule:MF_00576}; GN Name=gvpA {ECO:0000255|HAMAP-Rule:MF_00576, ECO:0000303|PubMed:11759840}; GN OrderedLocusNames=asl2254; GN and GN Name=gvpA2 {ECO:0000303|PubMed:32375647}; GN Synonyms=gvpB {ECO:0000303|PubMed:11759840}; OrderedLocusNames=asl2253; OS Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576). OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc. OX NCBI_TaxID=103690; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576; RX PubMed=11759840; DOI=10.1093/dnares/8.5.205; RA Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., RA Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., RA Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M., RA Takazawa M., Yamada M., Yasuda M., Tabata S.; RT "Complete genomic sequence of the filamentous nitrogen-fixing RT cyanobacterium Anabaena sp. strain PCC 7120."; RL DNA Res. 8:205-213(2001). RN [2] RP INDUCTION, LACK OF GAS VESICLES IN VIVO, AND FUNCTION IN E.COLI. RC STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576; RX PubMed=32375647; DOI=10.1186/s12866-020-01805-8; RA Cai K., Xu B.Y., Jiang Y.L., Wang Y., Chen Y., Zhou C.Z., Li Q.; RT "The model cyanobacteria Anabaena sp. PCC 7120 possess an intact but RT partially degenerated gene cluster encoding gas vesicles."; RL BMC Microbiol. 20:110-110(2020). CC -!- FUNCTION: Gas vesicles are hollow, gas filled proteinaceous CC nanostructures found in some microorganisms. During planktonic growth CC they allow positioning of the organism at a favorable depth for light CC or nutrient acquisition. GvpA forms the protein shell. CC {ECO:0000255|HAMAP-Rule:MF_00576}. CC -!- FUNCTION: Cluster expression in E.coli (gvpA1-gvpA2-gvpC-gvpN-gvpJ- CC gvpK-gvpF-gvpG-gvpV-gvpW) allows cells to float and produces CC irregularly shaped gas vesicles. {ECO:0000269|PubMed:32375647}. CC -!- SUBUNIT: The gas vesicle shell is 2 nm thick and consists of a single CC layer of this protein. It forms helical ribs nearly perpendicular to CC the long axis of the vesicle. {ECO:0000255|HAMAP-Rule:MF_00576}. CC -!- SUBCELLULAR LOCATION: Gas vesicle shell {ECO:0000255|HAMAP- CC Rule:MF_00576}. CC -!- INDUCTION: Constitutively transcribed when grown in a 12 hour CC light/dark regime at 2000 umol photon/m(2)/s; decreased light, growth CC at 38 degrees Celsius or both increased transcripts up to 23-fold. CC {ECO:0000269|PubMed:32375647}. CC -!- SIMILARITY: Belongs to the gas vesicle GvpA family. {ECO:0000255|HAMAP- CC Rule:MF_00576, ECO:0000305}. CC -!- CAUTION: Despite the presence of an intact gas vesicle cluster and gvpA CC transcripts, there is no evidence this strain produces gas vesicles. CC {ECO:0000269|PubMed:32375647}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BA000019; BAB73953.1; -; Genomic_DNA. DR EMBL; BA000019; BAB73952.1; -; Genomic_DNA. DR PIR; AF2087; AF2087. DR PIR; AG2087; AG2087. DR RefSeq; WP_010996411.1; NZ_RSCN01000004.1. DR AlphaFoldDB; Q8XFU1; -. DR SMR; Q8XFU1; -. DR STRING; 103690.17131344; -. DR EnsemblBacteria; BAB73952; BAB73952; BAB73952. DR EnsemblBacteria; BAB73953; BAB73953; BAB73953. DR GeneID; 58722719; -. DR KEGG; ana:asl2253; -. DR KEGG; ana:asl2254; -. DR eggNOG; ENOG5032YMQ; Bacteria. DR OMA; IDVWARV; -. DR OrthoDB; 284387at2; -. DR Proteomes; UP000002483; Chromosome. DR GO; GO:0033172; C:gas vesicle shell; IEA:UniProtKB-UniRule. DR GO; GO:0012506; C:vesicle membrane; IEA:InterPro. DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro. DR HAMAP; MF_00576; Gas_vesicle_A; 1. DR InterPro; IPR000638; Gas-vesicle_GvpA. DR InterPro; IPR018493; Gas-vesicle_GvpA_CS. DR PANTHER; PTHR35344; GAS VESICLE STRUCTURAL PROTEIN 2-RELATED; 1. DR PANTHER; PTHR35344:SF4; GAS VESICLE STRUCTURAL PROTEIN 2-RELATED; 1. DR Pfam; PF00741; Gas_vesicle; 1. DR PROSITE; PS00234; GAS_VESICLE_A_1; 1. DR PROSITE; PS00669; GAS_VESICLE_A_2; 1. PE 1: Evidence at protein level; KW Gas vesicle; Reference proteome. FT INIT_MET 1 FT /note="Removed" FT /evidence="ECO:0000250" FT CHAIN 2..71 FT /note="Gas vesicle protein A" FT /id="PRO_0000199979" SQ SEQUENCE 71 AA; 7547 MW; 804D215E7678EBFB CRC64; MAVEKTNSSS SLAEVIDRIL DKGIVVDAWV RVSLVGIELL AIEARIVIAS VETYLKYAEA VGLTQSAAMP A //