ID GVPA_NOSS1 Reviewed; 71 AA. AC Q8XFU1; DT 02-AUG-2002, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 3. DT 28-JUN-2023, entry version 89. DE RecName: Full=Gas vesicle protein A {ECO:0000255|HAMAP-Rule:MF_00576}; DE Short=GvpA {ECO:0000255|HAMAP-Rule:MF_00576}; GN Name=gvpA {ECO:0000255|HAMAP-Rule:MF_00576, ECO:0000303|PubMed:11759840}; GN OrderedLocusNames=asl2254; GN and GN Name=gvpA2 {ECO:0000303|PubMed:32375647}; GN Synonyms=gvpB {ECO:0000303|PubMed:11759840}; OrderedLocusNames=asl2253; OS Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576). OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc. OX NCBI_TaxID=103690; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576; RX PubMed=11759840; DOI=10.1093/dnares/8.5.205; RA Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., RA Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., RA Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M., RA Takazawa M., Yamada M., Yasuda M., Tabata S.; RT "Complete genomic sequence of the filamentous nitrogen-fixing RT cyanobacterium Anabaena sp. strain PCC 7120."; RL DNA Res. 8:205-213(2001). RN [2] RP INDUCTION. RC STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576; RX PubMed=32375647; DOI=10.1186/s12866-020-01805-8; RA Cai K., Xu B.Y., Jiang Y.L., Wang Y., Chen Y., Zhou C.Z., Li Q.; RT "The model cyanobacteria Anabaena sp. PCC 7120 possess an intact but RT partially degenerated gene cluster encoding gas vesicles."; RL BMC Microbiol. 20:110-110(2020). CC -!- FUNCTION: Gas vesicles are hollow, gas filled proteinaceous CC nanostructures found in some microorganisms. During planktonic growth CC they allow positioning of the organism at a favorable depth for light CC or nutrient acquisition. GvpA forms the protein shell. CC {ECO:0000255|HAMAP-Rule:MF_00576}. CC -!- SUBUNIT: The gas vesicle shell is 2 nm thick and consists of a single CC layer of this protein. It forms helical ribs nearly perpendicular to CC the long axis of the vesicle. {ECO:0000255|HAMAP-Rule:MF_00576}. CC -!- SUBCELLULAR LOCATION: Gas vesicle shell {ECO:0000255|HAMAP- CC Rule:MF_00576}. CC -!- INDUCTION: Constitutively transcribed when grown in a 12 h light/dark CC regime at 2000 umol photon/m(2)/s; decreased light, growth at 38 CC degrees Celsius or both increased transcripts up to 23-fold. CC {ECO:0000269|PubMed:32375647}. CC -!- SIMILARITY: Belongs to the gas vesicle protein type A family. CC {ECO:0000255|HAMAP-Rule:MF_00576, ECO:0000305}. CC -!- CAUTION: Despite the presence of an intact gas vesicle operon and gvpA CC transcripts, there is no evidence this strain produces gas vesicles. CC Operon expression in E.coli allows cells to float and produces CC irregularly shaped gas vesicles. {ECO:0000269|PubMed:32375647}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BA000019; BAB73953.1; -; Genomic_DNA. DR EMBL; BA000019; BAB73952.1; -; Genomic_DNA. DR PIR; AF2087; AF2087. DR PIR; AG2087; AG2087. DR RefSeq; WP_010996411.1; NZ_RSCN01000004.1. DR AlphaFoldDB; Q8XFU1; -. DR SMR; Q8XFU1; -. DR STRING; 103690.17131344; -. DR EnsemblBacteria; BAB73952; BAB73952; BAB73952. DR EnsemblBacteria; BAB73953; BAB73953; BAB73953. DR GeneID; 58722719; -. DR KEGG; ana:asl2253; -. DR KEGG; ana:asl2254; -. DR eggNOG; ENOG5032YMQ; Bacteria. DR OMA; IDVWARV; -. DR OrthoDB; 284387at2; -. DR Proteomes; UP000002483; Chromosome. DR GO; GO:0033172; C:gas vesicle shell; IEA:UniProtKB-SubCell. DR GO; GO:0005773; C:vacuole; IEA:UniProtKB-KW. DR GO; GO:0012506; C:vesicle membrane; IEA:InterPro. DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro. DR HAMAP; MF_00576; Gas_vesicle_A; 1. DR InterPro; IPR000638; Gas-vesicle_GvpA. DR InterPro; IPR018493; Gas-vesicle_GvpA_CS. DR PANTHER; PTHR35344; GAS VESICLE STRUCTURAL PROTEIN 2-RELATED; 1. DR PANTHER; PTHR35344:SF4; GAS VESICLE STRUCTURAL PROTEIN 2-RELATED; 1. DR Pfam; PF00741; Gas_vesicle; 1. DR PROSITE; PS00234; GAS_VESICLE_A_1; 1. DR PROSITE; PS00669; GAS_VESICLE_A_2; 1. PE 2: Evidence at transcript level; KW Gas vesicle; Reference proteome. FT INIT_MET 1 FT /note="Removed" FT /evidence="ECO:0000250" FT CHAIN 2..71 FT /note="Gas vesicle protein A" FT /id="PRO_0000199979" SQ SEQUENCE 71 AA; 7547 MW; 804D215E7678EBFB CRC64; MAVEKTNSSS SLAEVIDRIL DKGIVVDAWV RVSLVGIELL AIEARIVIAS VETYLKYAEA VGLTQSAAMP A //