ID Q8WWW8_HUMAN Unreviewed; 586 AA. AC Q8WWW8; DT 01-MAR-2002, integrated into UniProtKB/TrEMBL. DT 01-MAR-2002, sequence version 1. DT 06-FEB-2007, entry version 21. DE GRB2-associated-binding protein 3. GN Name=GAB3; ORFNames=hCG_18119; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=21602866; PubMed=11739737; DOI=10.1128/MCB.22.1.231-244.2002; RA Wolf I., Jenkins B.J., Liu Y., Seiffert M., Custodio J.M., Young P., RA Rohrschneider L.R.; RT "Gab3, a new DOS/Gab family member, facilitates macrophage RT differentiation."; RL Mol. Cell. Biol. 22:231-244(2002). CC -!- SIMILARITY: Contains 1 PH domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY057989; AAL25825.1; -; mRNA. DR EMBL; CH471172; EAW72667.1; -; Genomic_DNA. DR UniGene; Hs.496982; -. DR HSSP; Q9UN19; 1FAO. DR Ensembl; ENSG00000160219; Homo sapiens. DR HGNC; HGNC:17515; GAB3. DR ArrayExpress; Q8WWW8; -. DR RZPD-ProtExp; IOH42263; -. DR RZPD-ProtExp; T3575; -. DR InterPro; IPR001849; PH. DR InterPro; IPR011993; PH_type. DR Gene3D; G3DSA:2.30.29.30; PH_type; 1. DR Pfam; PF00169; PH; 1. DR SMART; SM00233; PH; 1. DR PROSITE; PS50003; PH_DOMAIN; 1. SQ SEQUENCE 586 AA; 65589 MW; 9DE0223C34AD8FFE CRC64; MSAGDAVCTG WLVKSPPERK LQRYAWRKRW FVLRRGRMSG NPDVLEYYRN KHSSKPIRVI DLSECAVWKH VGPSFVRKEF QNNFVFIVKT TSRTFYLVAK TEQEMQVWVH SISQVCNLGH LEDGADSMES LSYTPSSLQP SSASSLLTAH AASSSLPRDD PNTNAVATEE TRSESELLFL PDYLVLSNCE TGRLHHTSLP TRCDSWSNSD RSLEQASFDD VFVDCLQPLP SSHLVHPSCH GSGAQEVPSS RPQAALIWSR EINGPPRDHL SSSPLLESSL SSTIQVDKNQ GSLPCGAKEL DIMSNTPPPR PPKPSHLSER RQEEWSTHSG SKKPECTLVP RRISLSGLDN MRTWKADVEG QSLRHRDKRL SLNLPCRFSP MYPTASASIE DSYVPMSPQA GASGLGPHCS PDDYIPMNSG SISSPLPELP ANLEPPPVNR DLKPQRKSRP PPLDLRNLSI IREHASLTRT RTVPCSRTSF LSPERNGINS ARFFANPVSR EDEESYIEME EHRTASSLSS GALTWTKKFS LDYLALDFNS ASPAPMQQKL LLSEEQRVDY VQVDEQKTQA LQSTKQEWTD ERQSKV //