ID Q8VZA8_ARATH Unreviewed; 404 AA. AC Q8VZA8; DT 01-MAR-2002, integrated into UniProtKB/TrEMBL. DT 01-MAR-2002, sequence version 1. DT 08-NOV-2023, entry version 147. DE SubName: Full=PfkB-like carbohydrate kinase family protein {ECO:0000313|EMBL:AEE85531.1}; DE SubName: Full=Uncharacterized protein At4g28706 {ECO:0000313|EMBL:AAM91140.1}; GN OrderedLocusNames=At4g28706 {ECO:0000313|Araport:AT4G28706, GN ECO:0000313|EMBL:AEE85531.1}; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAL38271.1}; RN [1] {ECO:0000313|EMBL:AEE85531.1, ECO:0000313|Proteomes:UP000006548} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548}; RX PubMed=10617198; DOI=10.1038/47134; RG EU; RG CSHL and WU Arabidopsis Sequencing Project; RA Mayer K., Schuller C., Wambutt R., Murphy G., Volckaert G., Pohl T., RA Dusterhoft A., Stiekema W., Entian K.D., Terryn N., Harris B., Ansorge W., RA Brandt P., Grivell L., Rieger M., Weichselgartner M., de Simone V., RA Obermaier B., Mache R., Muller M., Kreis M., Delseny M., Puigdomenech P., RA Watson M., Schmidtheini T., Reichert B., Portatelle D., Perez-Alonso M., RA Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., RA Ridley P., Langham S.A., McCullagh B., Bilham L., Robben J., RA Van der Schueren J., Grymonprez B., Chuang Y.J., Vandenbussche F., RA Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., RA Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., RA Brandt A., Peters S., van Staveren M., Dirske W., Mooijman P., RA Klein Lankhorst R., Rose M., Hauf J., Kotter P., Berneiser S., Hempel S., RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., RA Gielen J., Villarroel R., De Clercq R., Van Montagu M., Rogers J., RA Cronin A., Quail M., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., RA Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., RA Benes V., Rechmann S., Borkova D., Blocker H., Scharfe M., Grimm M., RA Lohnert T.H., Dose S., de Haan M., Maarse A., Schafer M., Muller-Auer S., RA Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., RA Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., RA Quigley F., Clabauld G., Mundlein A., Felber R., Schnabl S., Hiller R., RA Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., RA Montfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., RA Mewes H.W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., RA Huang E., Spiegel L., Sehkon M., Murray J., Sheet P., Cordes M., RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L., Nelson J., RA Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., RA Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., RA O'Shaughnessy A., Rodriguez M., Hoffmann J., Till S., Granat S., Shohdy N., RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M., RA Martienssen R., McCombie W.R.; RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."; RL Nature 402:769-777(1999). RN [2] {ECO:0000313|EMBL:AAL38271.1} RP NUCLEOTIDE SEQUENCE. RA Nguyen M., Karlin-Neumann G., Southwick A., Lam B., Miranda M., Palm C.J., RA Bowser L., Jones T., Banh J., Carninci P., Chen H., Cheuk R., Chung M.K., RA Hayashizaki Y., Ishida J., Kamiya A., Kawai J., Kim C., Lin J., Liu S.X., RA Narusaka M., Pham P.K., Sakano H., Sakurai T., Satou M., Seki M., Shinn P., RA Yamada K., Shinozaki K., Ecker J., Theologis A., Davis R.W.; RL Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:AAM91140.1} RP NUCLEOTIDE SEQUENCE. RA Tripp M., Southwick A., Karlin-Neumann G., Nguyen M., Miranda M., RA Palm C.J., Bowser L., Jones T., Banh J., Carninci P., Chen H., Cheuk R., RA Chung M.K., Hayashizaki Y., Ishida J., Kamiya A., Kawai J., Kim C., Lin J., RA Liu S.X., Narusaka M., Pham P.K., Sakano H., Sakurai T., Satou M., Seki M., RA Shinn P., Yamada K., Shinozaki K., Ecker J., Theologis A., Davis R.W.; RL Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EMBL:AEE85531.1} RP NUCLEOTIDE SEQUENCE. RG TAIR; RA Swarbreck D., Lamesch P., Wilks C., Huala E.; RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases. RN [5] {ECO:0000313|EMBL:AEE85531.1} RP NUCLEOTIDE SEQUENCE. RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S., RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.; RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases. RN [6] {ECO:0000313|Proteomes:UP000006548} RP GENOME REANNOTATION. RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548}; RX PubMed=27862469; DOI=10.1111/tpj.13415; RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S., RA Town C.D.; RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference RT genome."; RL Plant J. 89:789-804(2017). CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family. CC {ECO:0000256|ARBA:ARBA00010688, ECO:0000256|RuleBase:RU003704}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY065095; AAL38271.1; -; mRNA. DR EMBL; AY128740; AAM91140.1; -; mRNA. DR EMBL; CP002687; AEE85531.1; -; Genomic_DNA. DR RefSeq; NP_849466.1; NM_179135.4. DR AlphaFoldDB; Q8VZA8; -. DR SMR; Q8VZA8; -. DR ProteomicsDB; 179495; -. DR EnsemblPlants; AT4G28706.2; AT4G28706.2; AT4G28706. DR GeneID; 828990; -. DR Gramene; AT4G28706.2; AT4G28706.2; AT4G28706. DR Araport; AT4G28706; -. DR TAIR; AT4G28706; -. DR Proteomes; UP000006548; Chromosome 4. DR ExpressionAtlas; Q8VZA8; baseline and differential. DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW. DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW. DR CDD; cd01945; ribokinase_group_B; 1. DR Gene3D; 3.40.1190.20; -; 1. DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS. DR InterPro; IPR011611; PfkB_dom. DR InterPro; IPR002139; Ribo/fructo_kinase. DR InterPro; IPR029056; Ribokinase-like. DR PANTHER; PTHR42774:SF3; PFKB-LIKE CARBOHYDRATE KINASE FAMILY PROTEIN; 1. DR PANTHER; PTHR42774; PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN; 1. DR Pfam; PF00294; PfkB; 2. DR PRINTS; PR00990; RIBOKINASE. DR SUPFAM; SSF53613; Ribokinase-like; 1. DR PROSITE; PS00584; PFKB_KINASES_2; 1. PE 1: Evidence at protein level; KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU003704}; KW Proteomics identification {ECO:0007829|PeptideAtlas:Q8VZA8, KW ECO:0007829|ProteomicsDB:Q8VZA8}; KW Reference proteome {ECO:0000313|Proteomes:UP000006548}; KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003704}. FT DOMAIN 57..279 FT /note="Carbohydrate kinase PfkB" FT /evidence="ECO:0000259|Pfam:PF00294" FT DOMAIN 336..393 FT /note="Carbohydrate kinase PfkB" FT /evidence="ECO:0000259|Pfam:PF00294" SQ SEQUENCE 404 AA; 43385 MW; CDE58C5FC12A80C2 CRC64; MLCFTHVPPL PLFSTSGIYL PASRRFTSFR IRMSSSSSID SVPPPPDNAI VLGCGGIAVD FLATVDSYPQ ADDKIRSTSL KVQGGGNAAN ALTCAARLGL NSRLISKVAN DSQGKGMLEE LEADGVDTSF IVVSKEGNSP FTYILVDNQT KTRTCIHTPG DPPMLPTDLS QSSMLSALDR ASIVYFDVRL HETALVIAKE ASRKKIPILV DTEKKRDGLD DLLPFADYVV CPENFPQTWT EVSSTPGALV SMLLRLPKLK FVIVTSGEHG CLMVQRASKA EVFESQETDI ESLLETLKHR KDSTTTFPTC VSSETTKLKA NGVGTMTGRL FLGTAEKIPP EELVDTTGAG DAFIGAVLYA ICAGMPPEKM LPFAAQVAGC SCRALGARTG LPHRTDPRLV PFLV //