ID   Q8VGG2_MOUSE            Unreviewed;       311 AA.
AC   Q8VGG2;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   09-DEC-2015, entry version 103.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU000688};
GN   Name=Olfr1221 {ECO:0000313|EMBL:AAP71621.1};
GN   ORFNames=mCG_141985 {ECO:0000313|EMBL:EDL27448.1};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAL60849.1};
RN   [1] {ECO:0000313|EMBL:AAL60849.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA   Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA   Trask B.J.;
RT   "Different evolutionary processes shaped the mouse and human olfactory
RT   receptor gene families.";
RL   Hum. Mol. Genet. 11:535-546(2002).
RN   [2] {ECO:0000313|EMBL:AAL60849.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11802173; DOI=10.1038/nn800;
RA   Zhang X., Firestein S.;
RT   "The olfactory receptor gene superfamily of the mouse.";
RL   Nat. Neurosci. 5:124-133(2002).
RN   [3] {ECO:0000313|EMBL:EDL27448.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Mixed {ECO:0000313|EMBL:EDL27448.1};
RX   PubMed=12040188; DOI=10.1126/science.1069193;
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R.,
RA   Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A.,
RA   Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.,
RA   Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K.,
RA   Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J.,
RA   Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R.,
RA   Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H.,
RA   Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A.,
RA   Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A.,
RA   Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C.,
RA   Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C.,
RA   Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B.,
RA   Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E.,
RA   Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R.,
RA   Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C.,
RA   Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L.,
RA   Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S.,
RA   Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L.,
RA   Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R.,
RA   Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R.,
RA   Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J.,
RA   Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L.,
RA   Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C.,
RA   Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A.,
RA   Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H.,
RA   Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L.,
RA   Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M.,
RA   Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K.,
RA   Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S.,
RA   Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J.,
RA   Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G.,
RA   Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.;
RT   "A comparison of whole-genome shotgun-derived mouse chromosome 16 and
RT   the human genome.";
RL   Science 296:1661-1671(2002).
RN   [4] {ECO:0000313|EMBL:AAL60849.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Adams M.;
RL   Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EMBL:AAP71621.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=14611657; DOI=10.1186/gb-2003-4-11-r71;
RA   Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A.,
RA   Walker M., Williams E.M., Trask B.J.;
RT   "Odorant receptor expressed sequence tags demonstrate olfactory
RT   expression of over 400 genes, extensive alternate splicing and unequal
RT   expression levels.";
RL   Genome Biol. 4:R71.1-R71.13(2003).
RN   [6] {ECO:0000313|EMBL:AAP71621.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Sanders K.;
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [7] {ECO:0000313|EMBL:EDL27448.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Mixed {ECO:0000313|EMBL:EDL27448.1};
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|SAAS:SAAS00407898}; Multi-pass membrane protein
CC       {ECO:0000256|SAAS:SAAS00407898}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688}.
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DR   EMBL; AY073186; AAL60849.1; -; Genomic_DNA.
DR   EMBL; AY318422; AAP71621.1; -; Genomic_DNA.
DR   EMBL; CH466519; EDL27448.1; -; Genomic_DNA.
DR   UniGene; Mm.330377; -.
DR   ProteinModelPortal; Q8VGG2; -.
DR   STRING; 10090.ENSMUSP00000097383; -.
DR   PaxDb; Q8VGG2; -.
DR   HOVERGEN; HBG017625; -.
DR   NextBio; 13885215; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|SAAS:SAAS00305704};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00132817};
KW   Membrane {ECO:0000256|SAAS:SAAS00132823, ECO:0000256|SAM:Phobius};
KW   Olfaction {ECO:0000256|SAAS:SAAS00305725};
KW   Receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00132805, ECO:0000313|EMBL:AAL60849.1};
KW   Sensory transduction {ECO:0000256|SAAS:SAAS00305715};
KW   Transducer {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00132822};
KW   Transmembrane {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00132812, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00132821,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     24     49       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     61     86       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     98    119       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    139    161       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    193    224       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    236    258       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    270    288       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       39    286       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   311 AA;  34941 MW;  636CA2A1F686D037 CRC64;
     MQNQSLVNEF ILLGLSQNTK VEKILFLLFL LIYLATIGGN MIIVATIIYS PALLGSPMYF
     FLVFLSLLDA CTSTVVTPKM IVGFFYERKI ISFEGCMTQL FAIHFFTAVE VIVLSAMAYD
     RYVAICKPLH YLSIMSKRVC GVLVGIAWAG GFLHSIIQIV FTLQLPFCGP NVIDHYMCDL
     FPLLKLACTD TQIFVILVFA NSGSICIIIF SLLLVSYGVI LFSLRAHSSE GRYKALSTCG
     SHITVVVLFF VPCILIYARP SSPFSFEKNT LIFANVLTPL LNPMVYTFRN KEMKSAIRKM
     WKRLVVVSDK Y
//