ID Q8VBX9_MOUSE Unreviewed; 221 AA. AC Q8VBX9; DT 01-MAR-2002, integrated into UniProtKB/TrEMBL. DT 01-MAR-2002, sequence version 1. DT 12-JUN-2007, entry version 41. DE Pax6 paired-less isoform. GN Name=Pax6; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6; TISSUE=Eye, and Brain; RX MEDLINE=22306463; PubMed=12419357; DOI=10.1016/S0003-2697(02)00244-0; RA Gorlov I.P., Saunders G.F.; RT "A method for isolating alternatively spliced isoforms: isolation of RT murine Pax6 isoforms."; RL Anal. Biochem. 308:401-404(2002). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6; TISSUE=Brain; RX MEDLINE=22371022; PubMed=12388550; DOI=10.1074/jbc.M206478200; RA Mishra R., Gorlov I.P., Chao L.Y., Singh S., Saunders G.F.; RT "PAX6, paired domain influences sequence recognition by the RT homeodomain."; RL J. Biol. Chem. 277:49488-49494(2002). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY064175; AAL40860.1; -; mRNA. DR EMBL; AF457141; AAL67742.1; -; mRNA. DR UniGene; Mm.3608; -. DR HSSP; P06601; 1FJL. DR SMR; Q8VBX9; 10-77. DR Ensembl; ENSMUSG00000027168; Mus musculus. DR MGI; MGI:97490; Pax6. DR ArrayExpress; Q8VBX9; -. DR RZPD-ProtExp; IOM20338; -. DR GO; GO:0005667; C:transcription factor complex; TAS:MGI. DR GO; GO:0003700; F:transcription factor activity; TAS:MGI. DR GO; GO:0009952; P:anterior/posterior pattern formation; IGI:MGI. DR GO; GO:0009952; P:anterior/posterior pattern formation; IMP:MGI. DR GO; GO:0007411; P:axon guidance; IMP:MGI. DR GO; GO:0001709; P:cell fate determination; IMP:MGI. DR GO; GO:0009950; P:dorsal/ventral axis specification; IMP:MGI. DR GO; GO:0042462; P:eye photoreceptor cell development; IMP:MGI. DR GO; GO:0008285; P:negative regulation of cell proliferation; IMP:MGI. DR GO; GO:0045665; P:negative regulation of neuron differentiation; IGI:MGI. DR GO; GO:0001764; P:neuron migration; IMP:MGI. DR GO; GO:0021983; P:pituitary gland development; IMP:MGI. DR GO; GO:0045944; P:positive regulation of transcription from R...; IDA:MGI. DR GO; GO:0030334; P:regulation of cell migration; IMP:MGI. DR GO; GO:0050767; P:regulation of neurogenesis; IMP:MGI. DR GO; GO:0007435; P:salivary gland morphogenesis; IMP:MGI. DR InterPro; IPR001356; Homeobox. DR InterPro; IPR012287; Homeodomain-rel. DR Gene3D; G3DSA:1.10.10.60; Homeodomain-rel. DR Pfam; PF00046; Homeobox; 1. DR PRINTS; PR00024; HOMEOBOX. DR ProDom; PD000010; Homeobox. DR SMART; SM00389; HOX. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. KW DNA-binding; Homeobox; Nuclear protein; Transcription; KW Transcription regulation. SQ SEQUENCE 221 AA; 24949 MW; 2B5AECC2464BBCE3 CRC64; MRLQLKRKLQ RNRTSFTQEQ IEALEKEFER THYPDVFARE RLAAKIDLPE ARIQVWFSNR RAKWRREEKL RNQRRQASNT PSHIPISSSF STSVYQPIPQ PTTPVSSFTS GSMLGRTDTA LTNTYSALPP MPSFTMANNL PMQPPVPSQT SSYSCMLPTS PSVNGRSYDT YTPPHMQTHM NSQPMGTSGT TSTGLISPGV SVPVQVPGSE PDMSQYWPRL Q //