ID Q8VBX9_MOUSE PRELIMINARY; PRT; 221 AA. AC Q8VBX9; DT 01-MAR-2002, integrated into UniProtKB/TrEMBL. DT 01-MAR-2002, sequence version 1. DT 18-APR-2006, entry version 27. DE Pax6 paired-less isoform. GN Name=Pax6; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6; TISSUE=Brain, and Eye; RX MEDLINE=22306463; PubMed=12419357; DOI=10.1016/S0003-2697(02)00244-0; RA Gorlov I.P., Saunders G.F.; RT "A method for isolating alternatively spliced isoforms: isolation of RT murine Pax6 isoforms."; RL Anal. Biochem. 308:401-404(2002). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6; TISSUE=Brain; RX MEDLINE=22371022; PubMed=12388550; DOI=10.1074/jbc.M206478200; RA Mishra R., Gorlov I.P., Chao L.Y., Singh S., Saunders G.F.; RT "PAX6, Paired Domain Influences Sequence Recognition by the RT Homeodomain."; RL J. Biol. Chem. 277:49488-49494(2002). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY064175; AAL40860.1; -; mRNA. DR EMBL; AF457141; AAL67742.1; -; mRNA. DR HSSP; P06601; 1FJL. DR SMR; Q8VBX9; 10-77. DR Ensembl; ENSMUSG00000027168; Mus musculus. DR MGI; MGI:97490; Pax6. DR GO; GO:0005634; C:nucleus; IDA. DR GO; GO:0005667; C:transcription factor complex; TAS. DR GO; GO:0003700; F:transcription factor activity; TAS. DR GO; GO:0009952; P:anterior/posterior pattern formation; IMP. DR GO; GO:0009952; P:anterior/posterior pattern formation; IGI. DR GO; GO:0007411; P:axon guidance; IMP. DR GO; GO:0001709; P:cell fate determination; IMP. DR GO; GO:0009953; P:dorsal/ventral pattern formation; IMP. DR GO; GO:0001747; P:eye development (sensu Mammalia); IGI. DR GO; GO:0001747; P:eye development (sensu Mammalia); IMP. DR GO; GO:0042462; P:eye photoreceptor cell development; IMP. DR GO; GO:0030900; P:forebrain development; IMP. DR GO; GO:0008285; P:negative regulation of cell proliferation; IMP. DR GO; GO:0001764; P:neuron migration; IMP. DR GO; GO:0045944; P:positive regulation of transcription from R...; IDA. DR GO; GO:0030334; P:regulation of cell migration; IMP. DR GO; GO:0050767; P:regulation of neurogenesis; IMP. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; TAS. DR GO; GO:0007435; P:salivary gland morphogenesis; IMP. DR InterPro; IPR001356; Homeobox. DR InterPro; IPR012287; Homeodomain-rel. DR InterPro; IPR009057; Homeodomain_like. DR InterPro; IPR007104; Paired_homeo. DR Pfam; PF00046; Homeobox; 1. DR PRINTS; PR00024; HOMEOBOX. DR ProDom; PD000010; Homeobox; 1. DR SMART; SM00389; HOX; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. KW DNA-binding; Homeobox; Nuclear protein. SQ SEQUENCE 221 AA; 24949 MW; 2B5AECC2464BBCE3 CRC64; MRLQLKRKLQ RNRTSFTQEQ IEALEKEFER THYPDVFARE RLAAKIDLPE ARIQVWFSNR RAKWRREEKL RNQRRQASNT PSHIPISSSF STSVYQPIPQ PTTPVSSFTS GSMLGRTDTA LTNTYSALPP MPSFTMANNL PMQPPVPSQT SSYSCMLPTS PSVNGRSYDT YTPPHMQTHM NSQPMGTSGT TSTGLISPGV SVPVQVPGSE PDMSQYWPRL Q //