ID   Q8UTE4_9HIV1            Unreviewed;       207 AA.
AC   Q8UTE4;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   10-FEB-2009, entry version 37.
DE   RecName: Full=Protein Nef;
GN   Name=nef;
OS   Human immunodeficiency virus 1.
OC   Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae;
OC   Lentivirus; Primate lentivirus group.
OX   NCBI_TaxID=11676;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=21988475; PubMed=11991972;
RX   DOI=10.1128/JVI.76.11.5435-5451.2002;
RA   Novitsky V., Smith U.R., Gilbert P., McLane M.F., Chigwedere P.,
RA   Williamson C., Ndung'u T., Klein I., Chang S.Y., Peter T., Thior I.,
RA   Foley B.T., Gaolekwe S., Rybak N., Gaseitsiwe S., Vannberg F.,
RA   Marlink R., Lee T.H., Essex M.;
RT   "Human immunodeficiency virus type 1 subtype C molecular phylogeny:
RT   consensus sequence for an AIDS vaccine design?";
RL   J. Virol. 76:5435-5451(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RA   Novitsky V.A., McLane M.F., Chigwedere P., Ndung'u T., Klein I.,
RA   Chang S.-Y., Peter T., Thior I., Rybak N., Gaseitsiwe S., Vannberg F.,
RA   Marlink R., Lee T.-H., Essex M.;
RL   Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the lentivirus primate group Nef protein
CC       family.
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DR   EMBL; AF443090; AAL34705.1; -; Genomic_DNA.
DR   HSSP; P04324; 1ZEC.
DR   SMR; Q8UTE4; 2-57.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   InterPro; IPR001558; HIV_Nef.
DR   Gene3D; G3DSA:3.30.62.10; HIV_Nef; 1.
DR   Pfam; PF00469; F-protein; 1.
DR   ProDom; PD000031; HIV_Nef; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Myristate; Viral immunoevasion;
KW   Virulence.
SQ   SEQUENCE   207 AA;  23618 MW;  CC6F0D421A738DE0 CRC64;
     MGGKWSKSSL TGWPAVRERI RRTEPAAEGV GEASQDLDKH GALTTSNTAA NNADCAWLQA
     HEEEGEVGFP VRPQVPLRPM TFKGAFDLGF FLKEKGGLEG LIWSQKRQDI LDLWVYHTQG
     YFPDWQNYTP GPGVRYPLTF GWPFKLVPVD PTEVEEANEG ENNCLLHPMS QHGMDDKDRE
     VLKWQFDSSL VRRHMARELH PEYYKDC
//