ID Q8T9L0_DROME Unreviewed; 371 AA. AC Q8T9L0; DT 01-JUN-2002, integrated into UniProtKB/TrEMBL. DT 01-JUN-2002, sequence version 1. DT 13-FEB-2019, entry version 79. DE SubName: Full=GM01975p {ECO:0000313|EMBL:AAL39391.1}; GN Name=Drp1 {ECO:0000313|FlyBase:FBgn0026479}; GN Synonyms=noodle {ECO:0000313|FlyBase:FBgn0026479}; GN ORFNames=CG3210 {ECO:0000313|EMBL:AAL39391.1, GN ECO:0000313|FlyBase:FBgn0026479}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAL39391.1}; RN [1] {ECO:0000313|EMBL:AAL39391.1} RP NUCLEOTIDE SEQUENCE. RA Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., RA Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., RA Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., RA Nunoo J., Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., RA Yu C., Lewis S.E., Rubin G.M., Celniker S.; RL Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY069246; AAL39391.1; -; mRNA. DR PeptideAtlas; Q8T9L0; -. DR PRIDE; Q8T9L0; -. DR FlyBase; FBgn0026479; Drp1. DR eggNOG; KOG0446; Eukaryota. DR eggNOG; COG0699; LUCA. DR Reactome; R-DME-75153; Apoptotic execution phase. DR ChiTaRS; Drp1; fly. DR Bgee; FBgn0026479; Expressed in 31 organ(s), highest expression level in embryonic/larval hemocyte (Drosophila). DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central. DR GO; GO:0016020; C:membrane; IBA:GO_Central. DR GO; GO:0005875; C:microtubule associated complex; ISS:FlyBase. DR GO; GO:0031966; C:mitochondrial membrane; IBA:GO_Central. DR GO; GO:0098793; C:presynapse; IEA:GOC. DR GO; GO:0005525; F:GTP binding; IEA:InterPro. DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central. DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central. DR GO; GO:0008637; P:apoptotic mitochondrial changes; IBA:GO_Central. DR GO; GO:0003374; P:dynamin family protein polymerization involved in mitochondrial fission; IBA:GO_Central. DR GO; GO:0048312; P:intracellular distribution of mitochondria; IBA:GO_Central. DR GO; GO:0061025; P:membrane fusion; IBA:GO_Central. DR GO; GO:0000266; P:mitochondrial fission; IBA:GO_Central. DR GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IBA:GO_Central. DR GO; GO:0051646; P:mitochondrion localization; IMP:FlyBase. DR GO; GO:0007005; P:mitochondrion organization; IMP:FlyBase. DR GO; GO:0000281; P:mitotic cytokinesis; IMP:FlyBase. DR GO; GO:0016559; P:peroxisome fission; IEA:InterPro. DR GO; GO:0090141; P:positive regulation of mitochondrial fission; IMP:FlyBase. DR GO; GO:1903146; P:regulation of autophagy of mitochondrion; IBA:GO_Central. DR GO; GO:0090140; P:regulation of mitochondrial fission; IMP:FlyBase. DR GO; GO:0010821; P:regulation of mitochondrion organization; IBA:GO_Central. DR GO; GO:0030382; P:sperm mitochondrion organization; IMP:FlyBase. DR GO; GO:0016185; P:synaptic vesicle budding from presynaptic endocytic zone membrane; NAS:FlyBase. DR GO; GO:0007370; P:ventral furrow formation; IMP:FlyBase. DR InterPro; IPR030556; DNM1L. DR InterPro; IPR000375; Dynamin_central. DR InterPro; IPR022812; Dynamin_SF. DR InterPro; IPR003130; GED. DR InterPro; IPR020850; GED_dom. DR PANTHER; PTHR11566; PTHR11566; 1. DR PANTHER; PTHR11566:SF39; PTHR11566:SF39; 1. DR Pfam; PF01031; Dynamin_M; 1. DR Pfam; PF02212; GED; 1. DR SMART; SM00302; GED; 1. DR PROSITE; PS51388; GED; 1. PE 2: Evidence at transcript level; FT DOMAIN 279 370 GED. {ECO:0000259|PROSITE:PS51388}. SQ SEQUENCE 371 AA; 42389 MW; 9C8B29593CF20BBE CRC64; MGYIFHETFG RTLDSIHPLA GLSKMDILTA IRNATGPRPA LFVPEVSFEL LVKRQIRRLE EPSLRCVELI HEEMQRIVQH CGNEVQQEML RFPKLHEKIV DVVTQLLRRR LPHTNVMVEN IVAIELAYIN TKHPDFHKDA ALVPSLLKTD SDPYSQINLG QRRANTPRNH MSPQISSHSA GSQQPQQQQP PQPSSSQQQY SQVHEQNHVA ENSTPSMAST WLSNILPPAP TRPDSIENST NNTPVHNNIV SPVKPVNLLP DVPANHNPRR LTDKEQKDCD VIEHLIKSYF YIVRKSIQDS VPKAIMHFLV NYVKDNLQSE LVTHLYKSDK AETLLNESDH IAVRRKEAAD MLKALTRANH IISEIRETHM W //