ID KGUA_FUSNN STANDARD; PRT; 185 AA. AC Q8RHI9; DT 28-FEB-2003 (Rel. 41, Created) DT 28-FEB-2003 (Rel. 41, Last sequence update) DT 07-FEB-2006 (Rel. 49, Last annotation update) DE Guanylate kinase (EC 2.7.4.8) (GMP kinase). GN Name=gmk; OrderedLocusNames=FN2033; OS Fusobacterium nucleatum subsp. nucleatum. OC Bacteria; Fusobacteria; Fusobacterales; Fusobacteriaceae; OC Fusobacterium. OX NCBI_TaxID=76856; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 25586; RX MEDLINE=21886394; PubMed=11889109; RX DOI=10.1128/JB.184.7.2005-2018.2002; RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A., RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., RA Vasieva O., Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., RA Larsen N., D'Souza M., Walunas T., Pusch G., Haselkorn R., RA Fonstein M., Kyrpides N.C., Overbeek R.; RT "Genome sequence and analysis of the oral bacterium Fusobacterium RT nucleatum strain ATCC 25586."; RL J. Bacteriol. 184:2005-2018(2002). CC -!- FUNCTION: Essential for recycling GMP and indirectly, cGMP (By CC similarity). CC -!- CATALYTIC ACTIVITY: ATP + GMP = ADP + GDP. CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: Belongs to the guanylate kinase family. CC -!- SIMILARITY: Contains 1 guanylate kinase-like domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE009951; AAL94118.1; -; Genomic_DNA. DR HSSP; P15454; 1GKY. DR HAMAP; MF_00328; -; 1. DR InterPro; IPR008144; Guanylate_kin. DR InterPro; IPR008145; Guanylt/Ca. DR PANTHER; PTHR13740; Guanylate_kin; 1. DR Pfam; PF00625; Guanylate_kin; 1. DR SMART; SM00072; GuKc; 1. DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1. DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1. KW ATP-binding; Complete proteome; Kinase; Nucleotide-binding; KW Transferase. FT DOMAIN 4 181 Guanylate kinase-like. FT NP_BIND 11 18 ATP (By similarity). SQ SEQUENCE 185 AA; 21025 MW; 988EF86443662B96 CRC64; MSLGALYVVS GPSGAGKSTV CKLVRERLGI NLSISATSRK PRNGEQEGVD YFFITAEEFE RKIKNDDFLE YANVHGNYYG TLKSEVEERL KRGEKVLLEI DVQGGVQVKN KFPEANLIFF KTANKEELEK RLRGRNTDSE EVIQARLKNS LKELEYESKY DRVIINNEIE QACNDLISII ENGVK //