ID Q8R3X9_MOUSE Unreviewed; 219 AA. AC Q8R3X9; DT 01-JUN-2002, integrated into UniProtKB/TrEMBL. DT 01-JUN-2002, sequence version 1. DT 17-FEB-2016, entry version 77. DE SubName: Full=Pdgfb protein {ECO:0000313|EMBL:AAH23427.1}; DE Flags: Fragment; GN Name=Pdgfb {ECO:0000313|EMBL:AAH23427.1, ECO:0000313|MGI:MGI:97528}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH23427.1}; RN [1] {ECO:0000313|EMBL:AAH23427.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=FVB/N-3 {ECO:0000313|EMBL:AAH23427.1}; RC TISSUE=Mammary tumor. MMTV-LTR/INT3 model. 5 month old mouse. Taken by RC biopsy. {ECO:0000313|EMBL:AAH23427.1}; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., RA Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family. CC {ECO:0000256|RuleBase:RU003818}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC023427; AAH23427.1; -; mRNA. DR UniGene; Mm.144089; -. DR ProteinModelPortal; Q8R3X9; -. DR STRING; 10090.ENSMUSP00000000500; -. DR PaxDb; Q8R3X9; -. DR MGI; MGI:97528; Pdgfb. DR eggNOG; ENOG410IJ45; Eukaryota. DR eggNOG; ENOG410XWTB; LUCA. DR HOVERGEN; HBG053546; -. DR GO; GO:0016020; C:membrane; IEA:InterPro. DR GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW. DR Gene3D; 2.10.90.10; -; 1. DR InterPro; IPR029034; Cystine-knot_cytokine. DR InterPro; IPR023581; PD_growth_factor_CS. DR InterPro; IPR000072; PDGF/VEGF_dom. DR InterPro; IPR006782; PDGF_N. DR Pfam; PF00341; PDGF; 1. DR Pfam; PF04692; PDGF_N; 1. DR SMART; SM00141; PDGF; 1. DR SUPFAM; SSF57501; SSF57501; 1. DR PROSITE; PS00249; PDGF_1; 1. DR PROSITE; PS50278; PDGF_2; 1. PE 2: Evidence at transcript level; KW Growth factor {ECO:0000256|RuleBase:RU003818, KW ECO:0000256|SAAS:SAAS00421526}. FT DOMAIN 62 163 PDGF_2. {ECO:0000259|PROSITE:PS50278}. FT NON_TER 1 1 {ECO:0000313|EMBL:AAH23427.1}. SQ SEQUENCE 219 AA; 24889 MW; 71942618732CB32E CRC64; RTRGEELYEM LSDHSIRSFD DLQRLLHRDS VDEDGAELDL NMTRAHSGVE LESSSRGRRS LGSLAAAEPA VIAECKTRTE VFQISRNLID RTNANFLVWP PCVEVQRCSG CCNNRNVQCR ASQVQMRPVQ VRKIEIVRKK PIFKKATVTL EDHLACKCET IVTPRPVTRS PGTSREQRAK TPQARVTIRT VRIRRPPKGK HRKFKHTHDK AALKETLGA //