ID Q8R3X9_MOUSE Unreviewed; 219 AA. AC Q8R3X9; DT 01-JUN-2002, integrated into UniProtKB/TrEMBL. DT 01-JUN-2002, sequence version 1. DT 31-MAY-2011, entry version 50. DE SubName: Full=Pdgfb protein; DE Flags: Fragment; GN Name=Pdgfb; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=FVB/N-3; RC TISSUE=Mammary tumor. MMTV-LTR/INT3 model. 5 month old mouse. Taken by RC biopsy.; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC023427; AAH23427.1; -; mRNA. DR IPI; IPI00132238; -. DR UniGene; Mm.144089; -. DR HSSP; P01127; 1PDG. DR ProteinModelPortal; Q8R3X9; -. DR STRING; Q8R3X9; -. DR MGI; MGI:97528; Pdgfb. DR GeneTree; ENSGT00510000046755; -. DR HOVERGEN; HBG053546; -. DR InParanoid; Q8R3X9; -. DR ArrayExpress; Q8R3X9; -. DR Bgee; Q8R3X9; -. DR Genevestigator; Q8R3X9; -. DR GO; GO:0016020; C:membrane; IEA:InterPro. DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW. DR GO; GO:0030036; P:actin cytoskeleton organization; IDA:MGI. DR GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IMP:MGI. DR GO; GO:0030031; P:cell projection assembly; IDA:MGI. DR GO; GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IMP:MGI. DR GO; GO:0030336; P:negative regulation of cell migration; IGI:MGI. DR GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW. DR GO; GO:0030335; P:positive regulation of cell migration; IGI:MGI. DR GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IGI:MGI. DR GO; GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IDA:MGI. DR GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IDA:MGI. DR GO; GO:0006929; P:substrate-dependent cell migration; IDA:MGI. DR InterPro; IPR000072; PD_growth_factor. DR InterPro; IPR023581; PD_growth_factor_CS. DR InterPro; IPR006782; PDGF_N. DR Pfam; PF00341; PDGF; 1. DR Pfam; PF04692; PDGF_N; 1. DR SMART; SM00141; PDGF; 1. DR PROSITE; PS00249; PDGF_1; 1. DR PROSITE; PS50278; PDGF_2; 1. PE 2: Evidence at transcript level; KW Growth factor; Mitogen. FT NON_TER 1 1 SQ SEQUENCE 219 AA; 24889 MW; 71942618732CB32E CRC64; RTRGEELYEM LSDHSIRSFD DLQRLLHRDS VDEDGAELDL NMTRAHSGVE LESSSRGRRS LGSLAAAEPA VIAECKTRTE VFQISRNLID RTNANFLVWP PCVEVQRCSG CCNNRNVQCR ASQVQMRPVQ VRKIEIVRKK PIFKKATVTL EDHLACKCET IVTPRPVTRS PGTSREQRAK TPQARVTIRT VRIRRPPKGK HRKFKHTHDK AALKETLGA //