ID Q8R3X9_MOUSE Unreviewed; 219 AA. AC Q8R3X9; DT 01-JUN-2002, integrated into UniProtKB/TrEMBL. DT 01-JUN-2002, sequence version 1. DT 19-JAN-2010, entry version 41. DE SubName: Full=Pdgfb protein; DE Flags: Fragment; GN Name=Pdgfb; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=FVB/N-3; TISSUE=Mammary tumor. MMTV-LTR/INT3 model. 5 month old RC mouse. Taken by biopsy.; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC023427; AAH23427.1; -; mRNA. DR IPI; IPI00132238; -. DR UniGene; Mm.144089; -. DR HSSP; P01127; 1PDG. DR SMR; Q8R3X9; 67-161. DR STRING; Q8R3X9; -. DR Ensembl; ENSMUST00000000500; ENSMUSP00000000500; ENSMUSG00000000489; Mus musculus. DR MGI; MGI:97528; Pdgfb. DR HOVERGEN; Q8R3X9; -. DR InParanoid; Q8R3X9; -. DR ArrayExpress; Q8R3X9; -. DR Bgee; Q8R3X9; -. DR Genevestigator; Q8R3X9; -. DR GO; GO:0009986; C:cell surface; IEA:Compara. DR GO; GO:0005737; C:cytoplasm; IEA:Compara. DR GO; GO:0016020; C:membrane; IEA:InterPro. DR GO; GO:0043498; F:cell surface binding; IEA:Compara. DR GO; GO:0005518; F:collagen binding; IEA:Compara. DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW. DR GO; GO:0048407; F:platelet-derived growth factor binding; IEA:Compara. DR GO; GO:0005161; F:platelet-derived growth factor receptor bin...; IEA:Compara. DR GO; GO:0046982; F:protein heterodimerization activity; IEA:Compara. DR GO; GO:0042803; F:protein homodimerization activity; IEA:Compara. DR GO; GO:0016049; P:cell growth; IEA:Compara. DR GO; GO:0006260; P:DNA replication; IEA:Compara. DR GO; GO:0002548; P:monocyte chemotaxis; IEA:Compara. DR GO; GO:0010512; P:negative regulation of phosphatidylinositol...; IEA:Compara. DR GO; GO:0010544; P:negative regulation of platelet activation; IEA:Compara. DR GO; GO:0048008; P:platelet-derived growth factor receptor sig...; IEA:Compara. DR GO; GO:0043536; P:positive regulation of blood vessel endothe...; IEA:Compara. DR GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW. DR GO; GO:0050921; P:positive regulation of chemotaxis; IEA:Compara. DR GO; GO:0045740; P:positive regulation of DNA replication; IEA:Compara. DR GO; GO:0048146; P:positive regulation of fibroblast prolifera...; IEA:Compara. DR GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Compara. DR GO; GO:0014911; P:positive regulation of smooth muscle cell m...; IEA:Compara. DR GO; GO:0048661; P:positive regulation of smooth muscle cell p...; IEA:Compara. DR GO; GO:0032355; P:response to estradiol stimulus; IEA:Compara. DR GO; GO:0001666; P:response to hypoxia; IEA:Compara. DR GO; GO:0007179; P:transforming growth factor beta receptor si...; IEA:Compara. DR GO; GO:0042060; P:wound healing; IEA:Compara. DR InterPro; IPR000072; PD_growth_factor. DR InterPro; IPR015583; PDGF_B. DR InterPro; IPR006782; PDGF_N. DR PANTHER; PTHR11633:SF2; PDGF_B; 1. DR Pfam; PF00341; PDGF; 1. DR Pfam; PF04692; PDGF_N; 1. DR SMART; SM00141; PDGF; 1. DR PROSITE; PS00249; PDGF_1; 1. DR PROSITE; PS50278; PDGF_2; 1. PE 2: Evidence at transcript level; KW Growth factor; Mitogen. FT NON_TER 1 1 SQ SEQUENCE 219 AA; 24889 MW; 71942618732CB32E CRC64; RTRGEELYEM LSDHSIRSFD DLQRLLHRDS VDEDGAELDL NMTRAHSGVE LESSSRGRRS LGSLAAAEPA VIAECKTRTE VFQISRNLID RTNANFLVWP PCVEVQRCSG CCNNRNVQCR ASQVQMRPVQ VRKIEIVRKK PIFKKATVTL EDHLACKCET IVTPRPVTRS PGTSREQRAK TPQARVTIRT VRIRRPPKGK HRKFKHTHDK AALKETLGA //