ID Q8R3X9_MOUSE Unreviewed; 219 AA. AC Q8R3X9; DT 01-JUN-2002, integrated into UniProtKB/TrEMBL. DT 01-JUN-2002, sequence version 1. DT 10-JUL-2007, entry version 26. DE Pdgfb protein (Fragment). GN Name=Pdgfb; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=FVB/N-3; TISSUE=Mammary tumor. MMTV-LTR/INT3 model. 5 month old RC mouse. Taken by biopsy.; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=FVB/N-3; TISSUE=Mammary tumor. MMTV-LTR/INT3 model. 5 month old RC mouse. Taken by biopsy.; RA Strausberg R.; RL Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC023427; AAH23427.1; -; mRNA. DR UniGene; Mm.144089; -. DR HSSP; P01127; 1PDG. DR Ensembl; ENSMUSG00000000489; Mus musculus. DR MGI; MGI:97528; Pdgfb. DR ArrayExpress; Q8R3X9; -. DR GO; GO:0005615; C:extracellular space; RCA:MGI. DR GO; GO:0030036; P:actin cytoskeleton organization and biogenesis; IDA:MGI. DR GO; GO:0030031; P:cell projection biogenesis; IDA:MGI. DR GO; GO:0030336; P:negative regulation of cell migration; IGI:MGI. DR GO; GO:0001938; P:positive regulation of endothelial cell pro...; IGI:MGI. DR GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphoryla...; IDA:MGI. DR GO; GO:0006929; P:substrate-bound cell migration; IDA:MGI. DR InterPro; IPR002400; GF_cysknot. DR InterPro; IPR000072; PD_growth_factor. DR InterPro; IPR015583; PDGF_B. DR InterPro; IPR006782; PDGF_N. DR PANTHER; PTHR11633:SF2; PDGF_B; 1. DR Pfam; PF00341; PDGF; 1. DR Pfam; PF04692; PDGF_N; 1. DR PRINTS; PR00438; GFCYSKNOT. DR ProDom; PD001629; PD_growth_factor; 1. DR SMART; SM00141; PDGF; 1. DR PROSITE; PS00249; PDGF_1; 1. DR PROSITE; PS50278; PDGF_2; 1. KW Growth factor; Mitogen. FT NON_TER 1 1 SQ SEQUENCE 219 AA; 24889 MW; 71942618732CB32E CRC64; RTRGEELYEM LSDHSIRSFD DLQRLLHRDS VDEDGAELDL NMTRAHSGVE LESSSRGRRS LGSLAAAEPA VIAECKTRTE VFQISRNLID RTNANFLVWP PCVEVQRCSG CCNNRNVQCR ASQVQMRPVQ VRKIEIVRKK PIFKKATVTL EDHLACKCET IVTPRPVTRS PGTSREQRAK TPQARVTIRT VRIRRPPKGK HRKFKHTHDK AALKETLGA //