ID RT18C_MOUSE Reviewed; 143 AA. AC Q8R2L5; Q3UKN5; Q9D100; DT 19-OCT-2002, integrated into UniProtKB/Swiss-Prot. DT 01-JUN-2002, sequence version 1. DT 29-SEP-2021, entry version 135. DE RecName: Full=28S ribosomal protein S18c, mitochondrial; DE Short=MRP-S18-c; DE Short=Mrps18-c; DE Short=S18mt-c; DE AltName: Full=28S ribosomal protein S18-1, mitochondrial; DE Short=MRP-S18-1; DE Flags: Precursor; GN Name=Mrps18c; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=C57BL/6J; TISSUE=Embryo, and Placenta; RX PubMed=16141072; DOI=10.1126/science.1112014; RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J., RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.; RT "The transcriptional landscape of the mammalian genome."; RL Science 309:1559-1563(2005). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Mammary gland; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA project: RT the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [3] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Spleen, and RC Testis; RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and expression."; RL Cell 143:1174-1189(2010). CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S) CC which comprises a 12S rRNA and about 30 distinct proteins. CC {ECO:0000250|UniProtKB:P82917}. CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P82917}. CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS18 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK004139; BAB23188.1; -; mRNA. DR EMBL; AK145935; BAE26766.1; -; mRNA. DR EMBL; BC028442; AAH28442.1; -; mRNA. DR CCDS; CCDS19468.1; -. DR RefSeq; NP_081102.1; NM_026826.1. DR SMR; Q8R2L5; -. DR ComplexPortal; CPX-5301; 28S mitochondrial small ribosomal subunit. DR STRING; 10090.ENSMUSP00000016977; -. DR iPTMnet; Q8R2L5; -. DR PhosphoSitePlus; Q8R2L5; -. DR EPD; Q8R2L5; -. DR MaxQB; Q8R2L5; -. DR PaxDb; Q8R2L5; -. DR PeptideAtlas; Q8R2L5; -. DR PRIDE; Q8R2L5; -. DR ProteomicsDB; 262720; -. DR Antibodypedia; 56067; 113 antibodies. DR DNASU; 68735; -. DR Ensembl; ENSMUST00000016977; ENSMUSP00000016977; ENSMUSG00000016833. DR GeneID; 68735; -. DR KEGG; mmu:68735; -. DR UCSC; uc008yib.1; mouse. DR CTD; 51023; -. DR MGI; MGI:1915985; Mrps18c. DR VEuPathDB; HostDB:ENSMUSG00000016833; -. DR eggNOG; KOG3162; Eukaryota. DR GeneTree; ENSGT00390000003791; -. DR HOGENOM; CLU_139337_2_0_1; -. DR InParanoid; Q8R2L5; -. DR OMA; GYHKDLD; -. DR OrthoDB; 1592020at2759; -. DR PhylomeDB; Q8R2L5; -. DR TreeFam; TF315059; -. DR Reactome; R-MMU-5389840; Mitochondrial translation elongation. DR Reactome; R-MMU-5419276; Mitochondrial translation termination. DR BioGRID-ORCS; 68735; 15 hits in 64 CRISPR screens. DR ChiTaRS; Mrps18c; mouse. DR PRO; PR:Q8R2L5; -. DR Proteomes; UP000000589; Chromosome 5. DR RNAct; Q8R2L5; protein. DR Bgee; ENSMUSG00000016833; Expressed in adult mammalian kidney and 308 other tissues. DR Genevisible; Q8R2L5; MM. DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB. DR GO; GO:0005739; C:mitochondrion; HDA:MGI. DR GO; GO:0070181; F:small ribosomal subunit rRNA binding; IBA:GO_Central. DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central. DR GO; GO:0006412; P:translation; IEA:InterPro. DR Gene3D; 4.10.640.10; -; 1. DR InterPro; IPR001648; Ribosomal_S18. DR InterPro; IPR018275; Ribosomal_S18_CS. DR InterPro; IPR036870; Ribosomal_S18_sf. DR Pfam; PF01084; Ribosomal_S18; 1. DR SUPFAM; SSF46911; SSF46911; 1. DR TIGRFAMs; TIGR00165; S18; 1. DR PROSITE; PS00057; RIBOSOMAL_S18; 1. PE 1: Evidence at protein level; KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein; KW Transit peptide. FT TRANSIT 1..? FT /note="Mitochondrion" FT /evidence="ECO:0000255" FT CHAIN ?..143 FT /note="28S ribosomal protein S18c, mitochondrial" FT /id="PRO_0000030630" FT CONFLICT 37 FT /note="R -> Q (in Ref. 1; BAB23188)" FT /evidence="ECO:0000305" SQ SEQUENCE 143 AA; 16275 MW; DD5926769541F2B6 CRC64; MAALVALCSG IGRKNLTTAA GCFTDRGTQA VSVIWRRCFS QFEQVTSNED LPVPMENPYK EPLKKCVLCE KRVDYKNVQL LSQFISPFTG CIYGRHITGL CGKKQREITK AIKRAQKMGF MPVTYKDPAY LKDPRVCNIR YRE //