ID RT18C_MOUSE Reviewed; 143 AA. AC Q8R2L5; Q3UKN5; Q9D100; DT 19-OCT-2002, integrated into UniProtKB/Swiss-Prot. DT 01-JUN-2002, sequence version 1. DT 08-MAY-2019, entry version 123. DE RecName: Full=28S ribosomal protein S18c, mitochondrial; DE Short=MRP-S18-c; DE Short=Mrps18-c; DE Short=S18mt-c; DE AltName: Full=28S ribosomal protein S18-1, mitochondrial; DE Short=MRP-S18-1; DE Flags: Precursor; GN Name=Mrps18c; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=C57BL/6J; TISSUE=Embryo, and Placenta; RX PubMed=16141072; DOI=10.1126/science.1112014; RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., RA Davis M.J., Wilming L.G., Aidinis V., Allen J.E., RA Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., RA Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., RA Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., RA Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., RA di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., RA Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., RA Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., RA Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., RA Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., RA Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., RA Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., RA Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., RA Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., RA Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., RA Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., RA Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., RA Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., RA Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., RA Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., RA Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., RA Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., RA Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., RA Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., RA Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., RA Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., RA Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., RA Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., RA Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., RA Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., RA Hayashizaki Y.; RT "The transcriptional landscape of the mammalian genome."; RL Science 309:1559-1563(2005). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Mammary gland; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [3] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Spleen, and RC Testis; RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit CC (28S) which comprises a 12S rRNA and about 30 distinct proteins. CC {ECO:0000250|UniProtKB:P82917}. CC -!- SUBCELLULAR LOCATION: Mitochondrion CC {ECO:0000250|UniProtKB:P82917}. CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS18 CC family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK004139; BAB23188.1; -; mRNA. DR EMBL; AK145935; BAE26766.1; -; mRNA. DR EMBL; BC028442; AAH28442.1; -; mRNA. DR CCDS; CCDS19468.1; -. DR RefSeq; NP_081102.1; NM_026826.1. DR SMR; Q8R2L5; -. DR STRING; 10090.ENSMUSP00000016977; -. DR iPTMnet; Q8R2L5; -. DR PhosphoSitePlus; Q8R2L5; -. DR EPD; Q8R2L5; -. DR MaxQB; Q8R2L5; -. DR PaxDb; Q8R2L5; -. DR PeptideAtlas; Q8R2L5; -. DR PRIDE; Q8R2L5; -. DR Ensembl; ENSMUST00000016977; ENSMUSP00000016977; ENSMUSG00000016833. DR GeneID; 68735; -. DR KEGG; mmu:68735; -. DR UCSC; uc008yib.1; mouse. DR CTD; 51023; -. DR MGI; MGI:1915985; Mrps18c. DR eggNOG; KOG3162; Eukaryota. DR eggNOG; COG0238; LUCA. DR GeneTree; ENSGT00390000003791; -. DR HOGENOM; HOG000218466; -. DR InParanoid; Q8R2L5; -. DR KO; K02963; -. DR OMA; YHKDLDF; -. DR OrthoDB; 1592020at2759; -. DR PhylomeDB; Q8R2L5; -. DR TreeFam; TF315059; -. DR Reactome; R-MMU-5389840; Mitochondrial translation elongation. DR Reactome; R-MMU-5419276; Mitochondrial translation termination. DR PRO; PR:Q8R2L5; -. DR Proteomes; UP000000589; Chromosome 5. DR Bgee; ENSMUSG00000016833; Expressed in 286 organ(s), highest expression level in brown adipose tissue. DR ExpressionAtlas; Q8R2L5; baseline and differential. DR Genevisible; Q8R2L5; MM. DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB. DR GO; GO:0005739; C:mitochondrion; HDA:MGI. DR GO; GO:0070181; F:small ribosomal subunit rRNA binding; IBA:GO_Central. DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central. DR GO; GO:0006412; P:translation; IEA:InterPro. DR Gene3D; 4.10.640.10; -; 1. DR InterPro; IPR001648; Ribosomal_S18. DR InterPro; IPR018275; Ribosomal_S18_CS. DR InterPro; IPR036870; Ribosomal_S18_sf. DR Pfam; PF01084; Ribosomal_S18; 1. DR ProDom; PD002239; Ribosomal_S18; 1. DR SUPFAM; SSF46911; SSF46911; 1. DR TIGRFAMs; TIGR00165; S18; 1. DR PROSITE; PS00057; RIBOSOMAL_S18; 1. PE 1: Evidence at protein level; KW Complete proteome; Mitochondrion; Reference proteome; KW Ribonucleoprotein; Ribosomal protein; Transit peptide. FT TRANSIT 1 ? Mitochondrion. {ECO:0000255}. FT CHAIN ? 143 28S ribosomal protein S18c, FT mitochondrial. FT /FTId=PRO_0000030630. FT CONFLICT 37 37 R -> Q (in Ref. 1; BAB23188). FT {ECO:0000305}. SQ SEQUENCE 143 AA; 16275 MW; DD5926769541F2B6 CRC64; MAALVALCSG IGRKNLTTAA GCFTDRGTQA VSVIWRRCFS QFEQVTSNED LPVPMENPYK EPLKKCVLCE KRVDYKNVQL LSQFISPFTG CIYGRHITGL CGKKQREITK AIKRAQKMGF MPVTYKDPAY LKDPRVCNIR YRE //