ID   OR5DD_HUMAN             Reviewed;         314 AA.
AC   Q8NGL4; Q6IF68; Q6IFC9;
DT   10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   10-OCT-2003, sequence version 2.
DT   29-SEP-2021, entry version 144.
DE   RecName: Full=Olfactory receptor 5D13;
DE   AltName: Full=Olfactory receptor OR11-142;
DE   AltName: Full=Olfactory receptor OR11-148;
GN   Name=OR5D13;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,
RA   Tsutsumi S., Aburatani H., Asai K., Akiyama Y.;
RT   "Genome-wide discovery and analysis of human seven transmembrane helix
RT   receptor genes.";
RL   Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=14983052; DOI=10.1073/pnas.0307882100;
RA   Malnic B., Godfrey P.A., Buck L.B.;
RT   "The human olfactory receptor gene family.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:2584-2589(2004).
RN   [3]
RP   ERRATUM OF PUBMED:14983052.
RA   Malnic B., Godfrey P.A., Buck L.B.;
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7205-7205(2004).
CC   -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC05998.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   -!- WEB RESOURCE: Name=Human Olfactory Receptor Data Exploratorium (HORDE);
CC       URL="http://genome.weizmann.ac.il/horde/card/index/symbol:OR5D13";
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB065778; BAC05998.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BK004333; DAA04731.1; -; Genomic_DNA.
DR   EMBL; BK004394; DAA04792.1; -; Genomic_DNA.
DR   RefSeq; NP_001001967.1; NM_001001967.1.
DR   STRING; 9606.ENSP00000354800; -.
DR   GlyGen; Q8NGL4; 1 site.
DR   iPTMnet; Q8NGL4; -.
DR   PhosphoSitePlus; Q8NGL4; -.
DR   BioMuta; OR5D13; -.
DR   DMDM; 38372723; -.
DR   PaxDb; Q8NGL4; -.
DR   PeptideAtlas; Q8NGL4; -.
DR   PRIDE; Q8NGL4; -.
DR   ProteomicsDB; 73548; -.
DR   Antibodypedia; 78666; 109 antibodies.
DR   DNASU; 390142; -.
DR   Ensembl; ENST00000623930; ENSP00000485428; ENSG00000279761.
DR   GeneID; 390142; -.
DR   KEGG; hsa:390142; -.
DR   UCSC; uc010ril.2; human.
DR   CTD; 390142; -.
DR   GeneCards; OR5D13; -.
DR   HGNC; HGNC:15280; OR5D13.
DR   HPA; ENSG00000279761; Not detected.
DR   neXtProt; NX_Q8NGL4; -.
DR   PharmGKB; PA32572; -.
DR   VEuPathDB; HostDB:ENSG00000279761; -.
DR   eggNOG; ENOG502TF14; Eukaryota.
DR   GeneTree; ENSGT01020000230400; -.
DR   HOGENOM; CLU_012526_5_5_1; -.
DR   InParanoid; Q8NGL4; -.
DR   OMA; FSGCIMQ; -.
DR   OrthoDB; 940316at2759; -.
DR   PhylomeDB; Q8NGL4; -.
DR   TreeFam; TF352746; -.
DR   PathwayCommons; Q8NGL4; -.
DR   Reactome; R-HSA-381753; Olfactory Signaling Pathway.
DR   BioGRID-ORCS; 390142; 6 hits in 570 CRISPR screens.
DR   GeneWiki; OR5D13; -.
DR   GenomeRNAi; 390142; -.
DR   Pharos; Q8NGL4; Tdark.
DR   PRO; PR:Q8NGL4; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   RNAct; Q8NGL4; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; TAS:Reactome.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR   GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0007608; P:sensory perception of smell; IBA:GO_Central.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane;
KW   Olfaction; Receptor; Reference proteome; Sensory transduction; Transducer;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..314
FT                   /note="Olfactory receptor 5D13"
FT                   /id="PRO_0000150591"
FT   TOPO_DOM        1..27
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..48
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        49..56
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        78..101
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        123..141
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        163..198
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        220..239
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        261..273
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        274..294
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        295..314
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        7
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   VARIANT         62
FT                   /note="C -> Y (in dbSNP:rs297118)"
FT                   /id="VAR_024099"
FT   VARIANT         124
FT                   /note="R -> H (in dbSNP:rs11230983)"
FT                   /id="VAR_024100"
FT   VARIANT         236
FT                   /note="R -> L (in dbSNP:rs7124871)"
FT                   /id="VAR_034220"
SQ   SEQUENCE   314 AA;  35447 MW;  CA6C3082912FD150 CRC64;
     MMASERNQSS TPTFILLGFS EYPEIQVPLF LVFLFVYTVT VVGNLGMIII IRLNSKLHTI
     MCFFLSHLSL TDFCFSTVVT PKLLENLVVE YRTISFSGCI MQFCFACIFG VTETFMLAAM
     AYDRFVAVCK PLLYTTIMSQ KLCALLVAGS YTWGIVCSLI LTYFLLDLSF CESTFINNFI
     CDHSVIVSAS YSDPYISQRL CFIIAIFNEV SSLIIILTSY MLIFTTIMKM RSASGRQKTF
     STCASHLTAI TIFHGTILFL YCVPNPKTSS LIVTVASVFY TVAIPMLNPL IYSLRNKDIN
     NMFEKLVVTK LIYH
//