ID OR7G1_HUMAN Reviewed; 333 AA. AC Q8NGA0; Q96RA1; DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot. DT 01-OCT-2002, sequence version 1. DT 02-SEP-2008, entry version 47. DE RecName: Full=Olfactory receptor 7G1; DE AltName: Full=Olfactory receptor 19-15; DE Short=OR19-15; GN Name=OR7G1; Synonyms=OR7G1P; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RA Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S., RA Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; RT "Genome-wide discovery and analysis of human seven transmembrane helix RT receptor genes."; RL Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 68-283. RX MEDLINE=22202146; PubMed=12213199; DOI=10.1006/geno.2002.6830; RA Fuchs T., Malecova B., Linhart C., Sharan R., Khen M., Herwig R., RA Shmulevich D., Elkon R., Steinfath M., O'Brien J.K., Radelof U., RA Lehrach H., Lancet D., Shamir R.; RT "DEFOG: a practical scheme for deciphering families of genes."; RL Genomics 80:295-302(2002). CC -!- FUNCTION: Odorant receptor (Potential). CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. CC -!- WEB RESOURCE: Name=Human Olfactory Receptor Data Exploratorium CC (HORDE); CC URL="http://bip.weizmann.ac.il/cgi-bin/HORDE/showGene.pl?key=symbol&value=OR7G1"; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB065926; BAC06141.1; -; Genomic_DNA. DR EMBL; AF399538; AAK95023.1; -; Genomic_DNA. DR RefSeq; NP_001005192.1; -. DR UniGene; Hs.553576; -. DR PhosphoSite; Q8NGA0; -. DR Ensembl; ENSG00000161807; Homo sapiens. DR GeneID; 125962; -. DR KEGG; hsa:125962; -. DR NMPDR; fig|9606.3.peg.15606; -. DR H-InvDB; HIX0040170; -. DR HGNC; HGNC:8465; OR7G1. DR PharmGKB; PA32737; -. DR HOGENOM; Q8NGA0; -. DR HOVERGEN; Q8NGA0; -. DR LinkHub; Q8NGA0; -. DR CleanEx; HS_OR7G1; -. DR InterPro; IPR000276; GPCR_Rhodpsn. DR InterPro; IPR017452; GPCR_Rhodpsn_supfam. DR InterPro; IPR000725; Olfact_rcpt. DR PANTHER; PTHR11398; Olfact_rcpt; 1. DR Pfam; PF00001; 7tm_1; 1. DR PRINTS; PR00237; GPCRRHODOPSN. DR PRINTS; PR00245; OLFACTORYR. DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. PE 2: Evidence at transcript level; KW Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane; KW Olfaction; Polymorphism; Receptor; Sensory transduction; Transducer; KW Transmembrane. FT CHAIN 1 333 Olfactory receptor 7G1. FT /FTId=PRO_0000150650. FT TOPO_DOM 1 25 Extracellular (Potential). FT TRANSMEM 26 46 1 (Potential). FT TOPO_DOM 47 54 Cytoplasmic (Potential). FT TRANSMEM 55 75 2 (Potential). FT TOPO_DOM 76 99 Extracellular (Potential). FT TRANSMEM 100 120 3 (Potential). FT TOPO_DOM 121 139 Cytoplasmic (Potential). FT TRANSMEM 140 160 4 (Potential). FT TOPO_DOM 161 197 Extracellular (Potential). FT TRANSMEM 198 217 5 (Potential). FT TOPO_DOM 218 237 Cytoplasmic (Potential). FT TRANSMEM 238 258 6 (Potential). FT TOPO_DOM 259 271 Extracellular (Potential). FT TRANSMEM 272 292 7 (Potential). FT TOPO_DOM 293 333 Cytoplasmic (Potential). FT CARBOHYD 5 5 N-linked (GlcNAc...) (Potential). FT CARBOHYD 89 89 N-linked (GlcNAc...) (Potential). FT DISULFID 97 189 By similarity. FT VARIANT 141 141 W -> C (in dbSNP:rs2217657). FT /FTId=VAR_034255. FT VARIANT 252 252 Y -> C (in dbSNP:rs2195951). FT /FTId=VAR_034256. SQ SEQUENCE 333 AA; 37110 MW; B496B9A6D5E69699 CRC64; MGPRNQTAVS EFLLMKVTED PELKLIPFSL FLSMYLVTIL GNLLILLAVI SDSHLHTPMY FLLFNLSFTD ICLTTTTVPK ILVNIQAQNQ SITYTGCLTQ ICLVLVFAGL ESCFLAVMAY DRYVAICHPL RYTVLMNVHF WGLLILLSMF MSTMDALVQS LMVLQLSFCK NVEIPLFFCE VVQVIKLACS DTLINNILIY FASSVFGAIP LSGIIFSYSQ IVTSVLRMPS ARGKYKAFST CGCHLSVFSL FYGTAFGVYI SSAVAESSRI TAVASVMYTV VPQMMNPFIY SLRNKEMKKA LRKLIGWSTV ARSRLTANSA SRVHAILLPR PPE //