ID Q8NDL6_HUMAN Unreviewed; 903 AA. AC Q8NDL6; DT 01-OCT-2002, integrated into UniProtKB/TrEMBL. DT 01-OCT-2002, sequence version 1. DT 12-AUG-2020, entry version 81. DE SubName: Full=Uncharacterized protein DKFZp434I2435 {ECO:0000313|EMBL:CAD38705.1}; DE Flags: Fragment; GN Name=DKFZp434I2435 {ECO:0000313|EMBL:CAD38705.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:CAD38705.1}; RN [1] {ECO:0000313|EMBL:CAD38705.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Testis {ECO:0000313|EMBL:CAD38705.1}; RG The German cDNA Consortium; RA Poustka A., Albert R., Moosmayer P., Schupp I., Wellenreuther R., RA Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S.; RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion CC {ECO:0000256|ARBA:ARBA00004246}. CC -!- SIMILARITY: Belongs to the PTEN phosphatase protein family. CC {ECO:0000256|ARBA:ARBA00007881}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL833845; CAD38705.1; -; mRNA. DR PeptideAtlas; Q8NDL6; -. DR PRIDE; Q8NDL6; -. DR SignaLink; Q8NDL6; -. DR CDD; cd01213; PTB_tensin; 1. DR CDD; cd09927; SH2_Tensin_like; 1. DR Gene3D; 2.30.29.30; -; 1. DR Gene3D; 3.30.505.10; -; 1. DR InterPro; IPR011993; PH-like_dom_sf. DR InterPro; IPR013625; PTB. DR InterPro; IPR006020; PTB/PI_dom. DR InterPro; IPR000980; SH2. DR InterPro; IPR036860; SH2_dom_sf. DR InterPro; IPR035012; Tensin-like_SH2. DR InterPro; IPR033929; Tensin_PTB. DR Pfam; PF08416; PTB; 1. DR Pfam; PF00017; SH2; 1. DR SMART; SM00462; PTB; 1. DR SMART; SM00252; SH2; 1. DR SUPFAM; SSF55550; SSF55550; 1. DR PROSITE; PS50001; SH2; 1. PE 2: Evidence at transcript level; KW Cell junction {ECO:0000256|ARBA:ARBA00022949}; KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE- KW ProRule:PRU00191}. FT DOMAIN 612..722 FT /note="SH2" FT /evidence="ECO:0000259|PROSITE:PS50001" FT REGION 54..135 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 157..209 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 299..421 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 465..496 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 516..567 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 861..891 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 70..84 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 159..173 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 350..390 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 550..567 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 861..885 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:CAD38705.1" SQ SEQUENCE 903 AA; 95877 MW; BBC1005D0753A18F CRC64; KQPQPLLRKP SVSAQMQAYG QSSYSTQTWV RQQQMVVAHQ YSFAPDGEAR LVSRCPADNP GLVQAQPRVP LTPTRGTSSR VAVQRGVGSG PHPPDTQQPS PSKAFKPRFP GDQVVNGAGP ELSTGPSPGS PTLDIDQSIE QLNRLILELD PTFEPIPTHM NALGSQANGS VSPDSVGGGL RASSRLPDTG EGPSRATGRQ GSSAEQPLGG RLRKLSLGQY DNDAGGQLPF SKCAWGKAGV DYAPNLPPFP SPADVKETMT PGYPQDLDII DGRILSSKES MCSTPAFPVS PETPYVKTAL RHPPFSPPEP PLSSPASQHK GGREPRSCPE TLTHAVGMSE SPIGPKSTML RADASSTPSF QQAFASSCTI SSNGPGQRRE SSSSAERQWV ESSPKPMVSL LGSGRPTGSP LSAEFSGTRK DSPVLSCFPP SELQAPFHSH ELSLAEPPDS LAPPSSQAFL GFGTAPVGSG LPPEEDLGAL LANSHGASPT PSIPLTATGA ADNGFLSHNF LTVAPGHSSH HSPGLQGQGV TLPGQPPLPE KKRASEGDRS LGSVSPSSSG FSSPHSGSTI SIPFPNVLPD FSKASEAASP LPDSPGDKLV IVKFVQDTSK FWYKADISRE QAIAMLKDKE PGSFIVRDSH SFRGAYGLAM KVATPPPSVL QLNKKAGDLA NELVRHFLIE CTPKGVRLKG CSNEPYFGSL TALVCQHSIT PLALPCKLLI PERDPLEEIA ESSPQTAANS AAELLKQGAA CNVWYLNSVE MESLTGHQAI QKALSITLVQ EPPPVSTVVH FKVSAQGITL TDNQRKLFFR RHYPVNSVIF CALDPQDRKW IKDGPSSKVF GFVARKQGSA TDNVCHLFAE HDPEQPARES QRHRGARDGP HEAMPRRHSG SPANVLFELI GQV //